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• W2109308211 abstract "Due to its large effect size, deep brain stimulation (DBS) is progressively considered in the treatment of medication-resistant Tourette's syndrome (TS) (1). Nevertheless, the underlying beneficial mechanisms of DBS in TS are still a matter of debate (2,3). Treatment strategies (D2-receptor antagonists) as well as previous research results point to a dysfunction of basal ganglia-related circuits and hyperactive dopaminergic innervations (4–8). It might thus be hypothesized that DBS acts via modulation of dopamine transmission; however, corresponding in vivo evidence is lacking, except for one positive single-patient [18F]fallypride-positron emission tomography (FP) investigation (9)." @default.
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• W2109308211 date "2012-03-01" @default.
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• W2109308211 title "In Vivo Evidence of Deep Brain Stimulation-Induced Dopaminergic Modulation in Tourette's Syndrome" @default.
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• W2109308211 doi "https://doi.org/10.1016/j.biopsych.2011.09.035" @default.
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