FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109331431> ?p ?o ?g. }

• W2109331431 endingPage "2846" @default.
• W2109331431 startingPage "2838" @default.
• W2109331431 abstract "ABSTRACT Escherichia coli is the primary cause of uncomplicated infections of the urinary tract including cystitis. More serious infections, characterized as acute pyelonephritis, can also develop. Type 1 fimbriae of E. coli contribute to virulence in the urinary tract; however, only recently has the expression of the type 1 fimbriae been investigated in vivo using molecular techniques. Transcription of type 1 fimbrial genes is controlled by a promoter that resides on a 314-bp invertible element capable of two orientations. One places the promoter in the ON orientation, allowing for transcription; the other places the promoter in the OFF orientation, preventing transcription. A PCR-based assay was developed to measure the orientation of the invertible element during an experimental urinary tract infection in mice. Using this assay, it was found that the percentage of the population ON in urine samples correlated with the respective CFU per gram of bladder ( P = 0.0006) but not with CFU per gram of kidney ( P > 0.069). Cystitis isolates present in the urine of mice during the course of infection had a higher percentage of their invertible elements in the ON orientation than did pyelonephritis isolates (85 and 34%, respectively, at 24 h; P < 0.0001). In general, cystitis isolates, unlike pyelonephritis isolates, were more likely to maintain their invertible elements in the ON orientation for the entire period of infection. E. coli cells expressing type 1 fimbriae, expelled in urine, were shown by scanning electron microscopy to be densely packed on the surface of uroepithelial cells. These results suggest that expression of type 1 fimbriae is more critical for cystitis strains than for pyelonephritis strains in the early stages of an infection during bladder colonization." @default.
• W2109331431 created "2016-06-24" @default.
• W2109331431 creator A5006179322 @default.
• W2109331431 creator A5014187004 @default.
• W2109331431 creator A5027643529 @default.
• W2109331431 creator A5088944578 @default.
• W2109331431 date "2001-05-01" @default.
• W2109331431 modified "2023-09-27" @default.
• W2109331431 title "In Vivo Dynamics of Type 1 Fimbria Regulation in Uropathogenic <i>Escherichia coli</i> during Experimental Urinary Tract Infection" @default.
• W2109331431 cites W1499426843 @default.
• W2109331431 cites W1502580664 @default.
• W2109331431 cites W1522226996 @default.
• W2109331431 cites W1527241561 @default.
• W2109331431 cites W1604287911 @default.
• W2109331431 cites W1648143438 @default.
• W2109331431 cites W1681088893 @default.
• W2109331431 cites W1812216994 @default.
• W2109331431 cites W1866086464 @default.
• W2109331431 cites W1890589065 @default.
• W2109331431 cites W1892978374 @default.
• W2109331431 cites W1911435502 @default.
• W2109331431 cites W1961971111 @default.
• W2109331431 cites W1964108835 @default.
• W2109331431 cites W1986705282 @default.
• W2109331431 cites W1992050568 @default.
• W2109331431 cites W1992057102 @default.
• W2109331431 cites W1999823179 @default.
• W2109331431 cites W2011711317 @default.
• W2109331431 cites W2036083275 @default.
• W2109331431 cites W2053138162 @default.
• W2109331431 cites W2074335785 @default.
• W2109331431 cites W2109499778 @default.
• W2109331431 cites W2113950929 @default.
• W2109331431 cites W2115332881 @default.
• W2109331431 cites W2118307978 @default.
• W2109331431 cites W2120176530 @default.
• W2109331431 cites W2132707683 @default.
• W2109331431 cites W2133188879 @default.
• W2109331431 cites W2141166258 @default.
• W2109331431 cites W2142983615 @default.
• W2109331431 cites W2143106471 @default.
• W2109331431 cites W2144498842 @default.
• W2109331431 cites W2151188021 @default.
• W2109331431 cites W2153432843 @default.
• W2109331431 cites W2162749433 @default.
• W2109331431 cites W2168753903 @default.
• W2109331431 cites W2192125289 @default.
• W2109331431 cites W2335509921 @default.
• W2109331431 doi "https://doi.org/10.1128/iai.69.5.2838-2846.2001" @default.
• W2109331431 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/98232" @default.
• W2109331431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11292696" @default.
• W2109331431 hasPublicationYear "2001" @default.
• W2109331431 type Work @default.
• W2109331431 sameAs 2109331431 @default.
• W2109331431 citedByCount "109" @default.
• W2109331431 countsByYear W21093314312012 @default.
• W2109331431 countsByYear W21093314312013 @default.
• W2109331431 countsByYear W21093314312014 @default.
• W2109331431 countsByYear W21093314312015 @default.
• W2109331431 countsByYear W21093314312016 @default.
• W2109331431 countsByYear W21093314312017 @default.
• W2109331431 countsByYear W21093314312018 @default.
• W2109331431 countsByYear W21093314312019 @default.
• W2109331431 countsByYear W21093314312020 @default.
• W2109331431 countsByYear W21093314312021 @default.
• W2109331431 countsByYear W21093314312022 @default.
• W2109331431 crossrefType "journal-article" @default.
• W2109331431 hasAuthorship W2109331431A5006179322 @default.
• W2109331431 hasAuthorship W2109331431A5014187004 @default.
• W2109331431 hasAuthorship W2109331431A5027643529 @default.
• W2109331431 hasAuthorship W2109331431A5088944578 @default.
• W2109331431 hasBestOaLocation W21093314311 @default.
• W2109331431 hasConcept C104317684 @default.
• W2109331431 hasConcept C105702510 @default.
• W2109331431 hasConcept C134018914 @default.
• W2109331431 hasConcept C138885662 @default.
• W2109331431 hasConcept C174832134 @default.
• W2109331431 hasConcept C179926584 @default.
• W2109331431 hasConcept C207001950 @default.
• W2109331431 hasConcept C2780026642 @default.
• W2109331431 hasConcept C2908647359 @default.
• W2109331431 hasConcept C2910768159 @default.
• W2109331431 hasConcept C39103817 @default.
• W2109331431 hasConcept C41895202 @default.
• W2109331431 hasConcept C54355233 @default.
• W2109331431 hasConcept C547475151 @default.
• W2109331431 hasConcept C60987743 @default.
• W2109331431 hasConcept C71924100 @default.
• W2109331431 hasConcept C77411442 @default.
• W2109331431 hasConcept C86803240 @default.
• W2109331431 hasConcept C89423630 @default.
• W2109331431 hasConcept C99454951 @default.
• W2109331431 hasConceptScore W2109331431C104317684 @default.
• W2109331431 hasConceptScore W2109331431C105702510 @default.
• W2109331431 hasConceptScore W2109331431C134018914 @default.
• W2109331431 hasConceptScore W2109331431C138885662 @default.
• W2109331431 hasConceptScore W2109331431C174832134 @default.
• W2109331431 hasConceptScore W2109331431C179926584 @default.

• next