Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109366969> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2109366969 endingPage "848" @default.
- W2109366969 startingPage "847" @default.
- W2109366969 abstract "Insulin-like growth factor-I acts as an important mediator between growth hormone and growth throughout fetal and childhood development. Its effects and those of the other insulin-like growth factors are modulated by at least six different binding proteins. The role of insulin-like growth factor-I in promoting cancer has been investigated for many years, but recently the quality and quantity of evidence has increased.1 In particular, a number of prospective studies using stored blood collected up to 14 years before the onset of disease have shown associations between insulin-like growth factor-I and prostate cancer, premenopausal breast cancer, and colon cancer.2-4The risk of cancer is higher among people with raised concentrations of insulin-like growth factor-I, and it is lower among those with high concentrations of insulin-like growth factor binding protein-3 (the main binding protein). The associations are similar when people whose blood samples were taken soon before diagnosis are excluded from analyses, suggesting that the observed relations are not due to the release of the growth factor by preclinical cancers.2-4 The effects are sizeable and stronger than the effects seen in relation to most previously reported risk factors.1 Weaker evidence from case-control studies suggests that the ratio of insulin-like growth factor-I to insulin-like growth factor binding protein-3 may …" @default.
- W2109366969 created "2016-06-24" @default.
- W2109366969 creator A5027462458 @default.
- W2109366969 creator A5045581195 @default.
- W2109366969 creator A5076124471 @default.
- W2109366969 date "2000-10-07" @default.
- W2109366969 modified "2023-10-09" @default.
- W2109366969 title "Cancer and insulin-like growth factor-I" @default.
- W2109366969 cites W1966719754 @default.
- W2109366969 cites W2004220005 @default.
- W2109366969 cites W2020636054 @default.
- W2109366969 cites W2023988468 @default.
- W2109366969 cites W2035897890 @default.
- W2109366969 cites W2043750439 @default.
- W2109366969 cites W2052374474 @default.
- W2109366969 cites W2073595273 @default.
- W2109366969 cites W2089415609 @default.
- W2109366969 cites W2113402231 @default.
- W2109366969 cites W2117350664 @default.
- W2109366969 cites W2150081825 @default.
- W2109366969 cites W2161484679 @default.
- W2109366969 cites W2165681440 @default.
- W2109366969 cites W2169163226 @default.
- W2109366969 cites W4236757670 @default.
- W2109366969 doi "https://doi.org/10.1136/bmj.321.7265.847" @default.
- W2109366969 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1118665" @default.
- W2109366969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11021847" @default.
- W2109366969 hasPublicationYear "2000" @default.
- W2109366969 type Work @default.
- W2109366969 sameAs 2109366969 @default.
- W2109366969 citedByCount "80" @default.
- W2109366969 countsByYear W21093669692012 @default.
- W2109366969 countsByYear W21093669692013 @default.
- W2109366969 countsByYear W21093669692014 @default.
- W2109366969 countsByYear W21093669692015 @default.
- W2109366969 countsByYear W21093669692016 @default.
- W2109366969 countsByYear W21093669692017 @default.
- W2109366969 countsByYear W21093669692019 @default.
- W2109366969 crossrefType "journal-article" @default.
- W2109366969 hasAuthorship W2109366969A5027462458 @default.
- W2109366969 hasAuthorship W2109366969A5045581195 @default.
- W2109366969 hasAuthorship W2109366969A5076124471 @default.
- W2109366969 hasBestOaLocation W21093669692 @default.
- W2109366969 hasConcept C126322002 @default.
- W2109366969 hasConcept C136764020 @default.
- W2109366969 hasConcept C170493617 @default.
- W2109366969 hasConcept C199360897 @default.
- W2109366969 hasConcept C2522767166 @default.
- W2109366969 hasConcept C2775960820 @default.
- W2109366969 hasConcept C2780689927 @default.
- W2109366969 hasConcept C2781039887 @default.
- W2109366969 hasConcept C41008148 @default.
- W2109366969 hasConcept C60644358 @default.
- W2109366969 hasConcept C71924100 @default.
- W2109366969 hasConcept C86803240 @default.
- W2109366969 hasConceptScore W2109366969C126322002 @default.
- W2109366969 hasConceptScore W2109366969C136764020 @default.
- W2109366969 hasConceptScore W2109366969C170493617 @default.
- W2109366969 hasConceptScore W2109366969C199360897 @default.
- W2109366969 hasConceptScore W2109366969C2522767166 @default.
- W2109366969 hasConceptScore W2109366969C2775960820 @default.
- W2109366969 hasConceptScore W2109366969C2780689927 @default.
- W2109366969 hasConceptScore W2109366969C2781039887 @default.
- W2109366969 hasConceptScore W2109366969C41008148 @default.
- W2109366969 hasConceptScore W2109366969C60644358 @default.
- W2109366969 hasConceptScore W2109366969C71924100 @default.
- W2109366969 hasConceptScore W2109366969C86803240 @default.
- W2109366969 hasIssue "7265" @default.
- W2109366969 hasLocation W21093669691 @default.
- W2109366969 hasLocation W21093669692 @default.
- W2109366969 hasLocation W21093669693 @default.
- W2109366969 hasOpenAccess W2109366969 @default.
- W2109366969 hasPrimaryLocation W21093669691 @default.
- W2109366969 hasRelatedWork W2014231481 @default.
- W2109366969 hasRelatedWork W2058160713 @default.
- W2109366969 hasRelatedWork W2099817208 @default.
- W2109366969 hasRelatedWork W2119436088 @default.
- W2109366969 hasRelatedWork W2121592873 @default.
- W2109366969 hasRelatedWork W2130733926 @default.
- W2109366969 hasRelatedWork W2590769241 @default.
- W2109366969 hasRelatedWork W2800670286 @default.
- W2109366969 hasRelatedWork W2982823661 @default.
- W2109366969 hasRelatedWork W2189320406 @default.
- W2109366969 hasVolume "321" @default.
- W2109366969 isParatext "false" @default.
- W2109366969 isRetracted "false" @default.
- W2109366969 magId "2109366969" @default.
- W2109366969 workType "article" @default.