FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109391946> ?p ?o ?g. }

• W2109391946 endingPage "1357" @default.
• W2109391946 startingPage "1338" @default.
• W2109391946 abstract "Iterative Stochastic Elimination (ISE) is a novel algorithm that was originally developed to solve extremely complex problems in protein structure and interactions, and has since been applied to diverse topics that share a few general “ingredients”: they are extremely complex, of combinatorial nature, may be presented as large sets of variables that can each have many alternative values, there is some interdependence of the variables on each other, and there is a scoring function that can evaluate each choice of the problems “configuration”; this is the set of single values of each of the variables that constitute its full presentation. Those are picked randomly in a large sample, the analysis of which allows decisions to be made for rejecting some values for each of the variables; thus resulting in a smaller set of potential combinations. This continues in iterations until the number of combinations allows all the remaining options to be computed exhaustively and to order them by their scores. ISE has been mainly applied to problems that are relevant to drug design and discovery. We demonstrate, among others, the use of ISE to determine the properties of molecular ensembles and to pick the best molecules (“focused libraries”) for hitting a specific target. Future ideas for using ISE are discussed, as well as mentioning its contributions to the construction of two start-up companies." @default.
• W2109391946 created "2016-06-24" @default.
• W2109391946 creator A5045868274 @default.
• W2109391946 creator A5059653025 @default.
• W2109391946 date "2014-08-01" @default.
• W2109391946 modified "2023-09-27" @default.
• W2109391946 title "Iterative Stochastic Elimination for Solving Complex Combinatorial Problems in Drug Discovery" @default.
• W2109391946 cites W1574994167 @default.
• W2109391946 cites W1964245184 @default.
• W2109391946 cites W1969131428 @default.
• W2109391946 cites W1975293246 @default.
• W2109391946 cites W1985588649 @default.
• W2109391946 cites W2001958300 @default.
• W2109391946 cites W2004303971 @default.
• W2109391946 cites W2009423060 @default.
• W2109391946 cites W2020601776 @default.
• W2109391946 cites W2027482274 @default.
• W2109391946 cites W2027815611 @default.
• W2109391946 cites W2029841034 @default.
• W2109391946 cites W2032842297 @default.
• W2109391946 cites W2038345112 @default.
• W2109391946 cites W2052030759 @default.
• W2109391946 cites W2063535987 @default.
• W2109391946 cites W2066962978 @default.
• W2109391946 cites W2074596609 @default.
• W2109391946 cites W2079191942 @default.
• W2109391946 cites W2080874085 @default.
• W2109391946 cites W2082660639 @default.
• W2109391946 cites W2090119198 @default.
• W2109391946 cites W2090917557 @default.
• W2109391946 cites W2096541451 @default.
• W2109391946 cites W2102377211 @default.
• W2109391946 cites W2104477830 @default.
• W2109391946 cites W2106648157 @default.
• W2109391946 cites W2114779636 @default.
• W2109391946 cites W2130233138 @default.
• W2109391946 cites W2130479394 @default.
• W2109391946 cites W2130686832 @default.
• W2109391946 cites W2132288856 @default.
• W2109391946 cites W2132866237 @default.
• W2109391946 cites W2133773344 @default.
• W2109391946 cites W2149658535 @default.
• W2109391946 cites W2158534713 @default.
• W2109391946 cites W2329190577 @default.
• W2109391946 cites W4248107770 @default.
• W2109391946 doi "https://doi.org/10.1002/ijch.201400072" @default.
• W2109391946 hasPublicationYear "2014" @default.
• W2109391946 type Work @default.
• W2109391946 sameAs 2109391946 @default.
• W2109391946 citedByCount "13" @default.
• W2109391946 countsByYear W21093919462016 @default.
• W2109391946 countsByYear W21093919462017 @default.
• W2109391946 countsByYear W21093919462018 @default.
• W2109391946 countsByYear W21093919462019 @default.
• W2109391946 countsByYear W21093919462021 @default.
• W2109391946 countsByYear W21093919462022 @default.
• W2109391946 countsByYear W21093919462023 @default.
• W2109391946 crossrefType "journal-article" @default.
• W2109391946 hasAuthorship W2109391946A5045868274 @default.
• W2109391946 hasAuthorship W2109391946A5059653025 @default.
• W2109391946 hasConcept C11413529 @default.
• W2109391946 hasConcept C114614502 @default.
• W2109391946 hasConcept C115908005 @default.
• W2109391946 hasConcept C134306372 @default.
• W2109391946 hasConcept C14036430 @default.
• W2109391946 hasConcept C177264268 @default.
• W2109391946 hasConcept C182365436 @default.
• W2109391946 hasConcept C185592680 @default.
• W2109391946 hasConcept C198531522 @default.
• W2109391946 hasConcept C199360897 @default.
• W2109391946 hasConcept C33923547 @default.
• W2109391946 hasConcept C41008148 @default.
• W2109391946 hasConcept C43617362 @default.
• W2109391946 hasConcept C55493867 @default.
• W2109391946 hasConcept C74187038 @default.
• W2109391946 hasConcept C78458016 @default.
• W2109391946 hasConcept C86803240 @default.
• W2109391946 hasConceptScore W2109391946C11413529 @default.
• W2109391946 hasConceptScore W2109391946C114614502 @default.
• W2109391946 hasConceptScore W2109391946C115908005 @default.
• W2109391946 hasConceptScore W2109391946C134306372 @default.
• W2109391946 hasConceptScore W2109391946C14036430 @default.
• W2109391946 hasConceptScore W2109391946C177264268 @default.
• W2109391946 hasConceptScore W2109391946C182365436 @default.
• W2109391946 hasConceptScore W2109391946C185592680 @default.
• W2109391946 hasConceptScore W2109391946C198531522 @default.
• W2109391946 hasConceptScore W2109391946C199360897 @default.
• W2109391946 hasConceptScore W2109391946C33923547 @default.
• W2109391946 hasConceptScore W2109391946C41008148 @default.
• W2109391946 hasConceptScore W2109391946C43617362 @default.
• W2109391946 hasConceptScore W2109391946C55493867 @default.
• W2109391946 hasConceptScore W2109391946C74187038 @default.
• W2109391946 hasConceptScore W2109391946C78458016 @default.
• W2109391946 hasConceptScore W2109391946C86803240 @default.
• W2109391946 hasIssue "8-9" @default.
• W2109391946 hasLocation W21093919461 @default.
• W2109391946 hasOpenAccess W2109391946 @default.
• W2109391946 hasPrimaryLocation W21093919461 @default.

• next