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- W2109410185 abstract "<h3>Purpose:</h3> To evaluate prospectively the relationship between appetite, food composition, nutritional habits and weight loss following administration of topiramate (TPM) and to identify predictors for TPM induced weight loss. <h3>Methods:</h3> 22 patients with epilepsy who were started on TPM were prospectively followed for 6 months and contacted again after a mean follow-up time of 37.1 months. <h3>Results:</h3> Body mass index (BMI) loss occurred in 59% of patients, with a mean weight loss of 9.5 kg after 6 months while receiving TPM without further weight loss at the long term follow-up. Weight loss was associated with reduction in appetite without affecting food composition. Predictors for BMI loss after 6 months were high initial BMI and body fat. After 3 weeks of treatment with TPM, the recorded parameters did not predict BMI loss but at 3 months, weight loss, reduction of appetite and amount of food intake were predictive for the amount of BMI loss after 6 months." @default.
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- W2109410185 date "2008-05-01" @default.
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- W2109410185 title "Topiramate, nutrition and weight change: a prospective study" @default.
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- W2109410185 doi "https://doi.org/10.1136/jnnp.2007.136929" @default.
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