FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109443341> ?p ?o ?g. }

• W2109443341 endingPage "299" @default.
• W2109443341 startingPage "293" @default.
• W2109443341 abstract "In parotid acinar cells, the activation of β-adrenergic receptors induces the accumulation of intracellular cAMP, and consequently provokes the exocytotic release of amylase, a digestive enzyme. The cellular redox status plays a pivotal role in regulating various cellular functions. Cellular redox imbalance caused by the oxidation of cellular antioxidants, as a result of oxidative stress, induces significant biological damage. In this study, we examined the effects of diamide, a thioloxidizing reagent, on amylase release by rat parotid acinar cells. In cells treated with diamide, the formation of cAMP and the release of amylase induced by the β-agonist isoproterenol (IPR) were partially reduced. The inhibitory effect of diamide on the IPR-induced release of amylase could be abrogated by reduced glutathione or dithiothreitol. Diamide had no effect on the amylase release induced by forskolin, an adenylate cyclase activator, or by mastoparan, a heterotrimeric GTPbinding protein activator. In cells treated with diamide, the binding affinity for [3H]DHA, but not the number of binding sites, was reduced. These results suggest that β-adrenergic receptor function is reduced by thiol-oxidation, which inhibits amylase secretion by parotid acinar cells." @default.
• W2109443341 created "2016-06-24" @default.
• W2109443341 creator A5001299245 @default.
• W2109443341 creator A5002860354 @default.
• W2109443341 creator A5030128184 @default.
• W2109443341 creator A5061663577 @default.
• W2109443341 creator A5072167836 @default.
• W2109443341 creator A5075444660 @default.
• W2109443341 creator A5083441938 @default.
• W2109443341 creator A5090984439 @default.
• W2109443341 date "2010-01-01" @default.
• W2109443341 modified "2023-09-23" @default.
• W2109443341 title "Thiol-oxidation reduces the release of amylase induced by β-adrenergic receptor activation in rat parotid acinar cells" @default.
• W2109443341 cites W1502005164 @default.
• W2109443341 cites W1563653502 @default.
• W2109443341 cites W1775749144 @default.
• W2109443341 cites W1820847166 @default.
• W2109443341 cites W1979655239 @default.
• W2109443341 cites W2000121254 @default.
• W2109443341 cites W2003373618 @default.
• W2109443341 cites W202219468 @default.
• W2109443341 cites W2025572547 @default.
• W2109443341 cites W2032237632 @default.
• W2109443341 cites W2035902417 @default.
• W2109443341 cites W2049873020 @default.
• W2109443341 cites W2058726923 @default.
• W2109443341 cites W2068102085 @default.
• W2109443341 cites W2070508983 @default.
• W2109443341 cites W2085707330 @default.
• W2109443341 cites W2090676036 @default.
• W2109443341 cites W2091886434 @default.
• W2109443341 cites W2093838410 @default.
• W2109443341 cites W2094170571 @default.
• W2109443341 cites W2101861123 @default.
• W2109443341 cites W2104349140 @default.
• W2109443341 cites W2118218196 @default.
• W2109443341 cites W2128635872 @default.
• W2109443341 cites W2136939062 @default.
• W2109443341 cites W2157363358 @default.
• W2109443341 cites W2167424396 @default.
• W2109443341 cites W2208451345 @default.
• W2109443341 cites W2316746624 @default.
• W2109443341 doi "https://doi.org/10.2220/biomedres.31.293" @default.
• W2109443341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21079359" @default.
• W2109443341 hasPublicationYear "2010" @default.
• W2109443341 type Work @default.
• W2109443341 sameAs 2109443341 @default.
• W2109443341 citedByCount "4" @default.
• W2109443341 countsByYear W21094433412012 @default.
• W2109443341 countsByYear W21094433412013 @default.
• W2109443341 countsByYear W21094433412017 @default.
• W2109443341 countsByYear W21094433412022 @default.
• W2109443341 crossrefType "journal-article" @default.
• W2109443341 hasAuthorship W2109443341A5001299245 @default.
• W2109443341 hasAuthorship W2109443341A5002860354 @default.
• W2109443341 hasAuthorship W2109443341A5030128184 @default.
• W2109443341 hasAuthorship W2109443341A5061663577 @default.
• W2109443341 hasAuthorship W2109443341A5072167836 @default.
• W2109443341 hasAuthorship W2109443341A5075444660 @default.
• W2109443341 hasAuthorship W2109443341A5083441938 @default.
• W2109443341 hasAuthorship W2109443341A5090984439 @default.
• W2109443341 hasBestOaLocation W21094433411 @default.
• W2109443341 hasConcept C126322002 @default.
• W2109443341 hasConcept C134018914 @default.
• W2109443341 hasConcept C170493617 @default.
• W2109443341 hasConcept C170835558 @default.
• W2109443341 hasConcept C181199279 @default.
• W2109443341 hasConcept C185592680 @default.
• W2109443341 hasConcept C2777824588 @default.
• W2109443341 hasConcept C2778938600 @default.
• W2109443341 hasConcept C2779276759 @default.
• W2109443341 hasConcept C538909803 @default.
• W2109443341 hasConcept C55493867 @default.
• W2109443341 hasConcept C71924100 @default.
• W2109443341 hasConcept C79879829 @default.
• W2109443341 hasConcept C86803240 @default.
• W2109443341 hasConcept C88045685 @default.
• W2109443341 hasConceptScore W2109443341C126322002 @default.
• W2109443341 hasConceptScore W2109443341C134018914 @default.
• W2109443341 hasConceptScore W2109443341C170493617 @default.
• W2109443341 hasConceptScore W2109443341C170835558 @default.
• W2109443341 hasConceptScore W2109443341C181199279 @default.
• W2109443341 hasConceptScore W2109443341C185592680 @default.
• W2109443341 hasConceptScore W2109443341C2777824588 @default.
• W2109443341 hasConceptScore W2109443341C2778938600 @default.
• W2109443341 hasConceptScore W2109443341C2779276759 @default.
• W2109443341 hasConceptScore W2109443341C538909803 @default.
• W2109443341 hasConceptScore W2109443341C55493867 @default.
• W2109443341 hasConceptScore W2109443341C71924100 @default.
• W2109443341 hasConceptScore W2109443341C79879829 @default.
• W2109443341 hasConceptScore W2109443341C86803240 @default.
• W2109443341 hasConceptScore W2109443341C88045685 @default.
• W2109443341 hasIssue "5" @default.
• W2109443341 hasLocation W21094433411 @default.
• W2109443341 hasLocation W21094433412 @default.
• W2109443341 hasOpenAccess W2109443341 @default.
• W2109443341 hasPrimaryLocation W21094433411 @default.
• W2109443341 hasRelatedWork W1975696001 @default.

• next