FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109452245> ?p ?o ?g. }

• W2109452245 abstract "AbstractTherapeutic hypothermia (TH) is the only treatment available to reduce neurological sequels for unconscious patients following cardiac arrest (CA). TH requires sedation and muscular relaxation, obscuring the clinical neurological examination for estimation of prognosis, and clinical decision making. Continuous amplitude-integrated EEG (aEEG) has been used to predict outcome in neonates suffering from asphyxia. In adults following CA and TH, the novel observation was made that a continuous aEEG-pattern prior to or at normothermia strongly correlated to return of consciousness, while other patterns strongly correlated to continued coma. A status epilepticus aEEG-pattern carried a poor, but not desolate prognosis. Biochemical neuronal-markers (neuron-specific enolase (NSE) and S-100B) have previously been assessed in non-TH CA patients. In TH, an NSE level of 28 μg/l 48h after CA, or an increase of more than 2 μg/l between 24 and 48h were strongly associated to a poor outcome.Five days after the CA, one third of the patients remained in coma. They either had multimodal signs of extensive brain damage (high NSE levels, ischemic changes on MRI or neurophysiological evidence of advanced brain damage (bilateral lack of SSEP)), or showed sustained unconsciousness and a status epilepticus aEEG-pattern. Unconscious patients without these signs of brain injury eventually regained consciousness.Approximately 50% of hypothermia treated patients regained consciousness. Ninety-eight percent of surviving patients had an independent lifestyle six months after the CA. The dominant cognitive problem was a disturbed memory function.Taken together, aEEG appears superior in early neurological prognostication in these patients." @default.
• W2109452245 created "2016-06-24" @default.
• W2109452245 creator A5016811769 @default.
• W2109452245 date "2010-01-01" @default.
• W2109452245 modified "2023-09-28" @default.
• W2109452245 title "Cardiac arrest and therapeutic hypothermia: Prognosis and outcome" @default.
• W2109452245 cites W1503600085 @default.
• W2109452245 cites W1544521591 @default.
• W2109452245 cites W1563399660 @default.
• W2109452245 cites W1590744179 @default.
• W2109452245 cites W1705562686 @default.
• W2109452245 cites W1714706046 @default.
• W2109452245 cites W1746578757 @default.
• W2109452245 cites W1874700596 @default.
• W2109452245 cites W1966349018 @default.
• W2109452245 cites W1967943152 @default.
• W2109452245 cites W1970168060 @default.
• W2109452245 cites W1970341483 @default.
• W2109452245 cites W1971199359 @default.
• W2109452245 cites W1973344958 @default.
• W2109452245 cites W1973406593 @default.
• W2109452245 cites W1973604810 @default.
• W2109452245 cites W1980446213 @default.
• W2109452245 cites W1980669612 @default.
• W2109452245 cites W1984505092 @default.
• W2109452245 cites W1985788035 @default.
• W2109452245 cites W1988756839 @default.
• W2109452245 cites W1989358571 @default.
• W2109452245 cites W1990432083 @default.
• W2109452245 cites W1990708266 @default.
• W2109452245 cites W1992861199 @default.
• W2109452245 cites W1993910831 @default.
• W2109452245 cites W1994088045 @default.
• W2109452245 cites W1994684892 @default.
• W2109452245 cites W1995454155 @default.
• W2109452245 cites W19985909 @default.
• W2109452245 cites W2000258296 @default.
• W2109452245 cites W2001983855 @default.
• W2109452245 cites W2004393051 @default.
• W2109452245 cites W2005225871 @default.
• W2109452245 cites W2006135584 @default.
• W2109452245 cites W2008283809 @default.
• W2109452245 cites W2013149846 @default.
• W2109452245 cites W2013246006 @default.
• W2109452245 cites W2018825346 @default.
• W2109452245 cites W2020765940 @default.
• W2109452245 cites W2021111947 @default.
• W2109452245 cites W2021460336 @default.
• W2109452245 cites W2023169605 @default.
• W2109452245 cites W2023246600 @default.
• W2109452245 cites W2026921254 @default.
• W2109452245 cites W2028422783 @default.
• W2109452245 cites W2031412579 @default.
• W2109452245 cites W2031417905 @default.
• W2109452245 cites W2033387388 @default.
• W2109452245 cites W2034752220 @default.
• W2109452245 cites W2035418204 @default.
• W2109452245 cites W2036252085 @default.
• W2109452245 cites W2039422069 @default.
• W2109452245 cites W2041131288 @default.
• W2109452245 cites W2043489785 @default.
• W2109452245 cites W2043776457 @default.
• W2109452245 cites W2045840821 @default.
• W2109452245 cites W2046728139 @default.
• W2109452245 cites W2046766588 @default.
• W2109452245 cites W2047034998 @default.
• W2109452245 cites W2049532021 @default.
• W2109452245 cites W2051026770 @default.
• W2109452245 cites W2052437034 @default.
• W2109452245 cites W2054367671 @default.
• W2109452245 cites W2054797341 @default.
• W2109452245 cites W2056821940 @default.
• W2109452245 cites W2057366091 @default.
• W2109452245 cites W2058156864 @default.
• W2109452245 cites W2059224729 @default.
• W2109452245 cites W2059270934 @default.
• W2109452245 cites W2060249985 @default.
• W2109452245 cites W2063322778 @default.
• W2109452245 cites W2064510098 @default.
• W2109452245 cites W2066171655 @default.
• W2109452245 cites W2066303941 @default.
• W2109452245 cites W2067855097 @default.
• W2109452245 cites W2068077095 @default.
• W2109452245 cites W2068145211 @default.
• W2109452245 cites W2070386709 @default.
• W2109452245 cites W2071141535 @default.
• W2109452245 cites W2071256185 @default.
• W2109452245 cites W2072913100 @default.
• W2109452245 cites W2074553712 @default.
• W2109452245 cites W2076163436 @default.
• W2109452245 cites W2077826388 @default.
• W2109452245 cites W2078694765 @default.
• W2109452245 cites W2079613960 @default.
• W2109452245 cites W2080656191 @default.
• W2109452245 cites W2082755928 @default.
• W2109452245 cites W2085640745 @default.
• W2109452245 cites W2088270787 @default.
• W2109452245 cites W2088781346 @default.
• W2109452245 cites W2089723417 @default.
• W2109452245 cites W2091308012 @default.

• next