FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109454141> ?p ?o ?g. }

• W2109454141 endingPage "484" @default.
• W2109454141 startingPage "474" @default.
• W2109454141 abstract "Recent development of deep sequencing technologies has facilitated de novo genome sequencing projects, now conducted even by individual laboratories. However, this will yield more and more genome sequences that are not well assembled, and will hinder thorough annotation when no closely related reference genome is available. One of the challenging issues is the identification of protein-coding sequences split into multiple unassembled genomic segments, which can confound orthology assignment and various laboratory experiments requiring the identification of individual genes. In this study, using the genome of a cartilaginous fish, Callorhinchus milii, as test case, we performed gene prediction using a model specifically trained for this genome. We implemented an algorithm, designated ESPRIT, to identify possible linkages between multiple protein-coding portions derived from a single genomic locus split into multiple unassembled genomic segments. We developed a validation framework based on an artificially fragmented human genome, improvements between early and recent mouse genome assemblies, comparison with experimentally validated sequences from GenBank, and phylogenetic analyses. Our strategy provided insights into practical solutions for efficient annotation of only partially sequenced (low-coverage) genomes. To our knowledge, our study is the first formulation of a method to link unassembled genomic segments based on proteomes of relatively distantly related species as references." @default.
• W2109454141 created "2016-06-24" @default.
• W2109454141 creator A5016113894 @default.
• W2109454141 creator A5041529580 @default.
• W2109454141 creator A5050068380 @default.
• W2109454141 creator A5062084820 @default.
• W2109454141 creator A5063629043 @default.
• W2109454141 creator A5089205418 @default.
• W2109454141 date "2011-06-28" @default.
• W2109454141 modified "2023-09-26" @default.
• W2109454141 title "Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes)" @default.
• W2109454141 cites W1484347389 @default.
• W2109454141 cites W1968191137 @default.
• W2109454141 cites W1992975997 @default.
• W2109454141 cites W2004575181 @default.
• W2109454141 cites W2008208329 @default.
• W2109454141 cites W2009646489 @default.
• W2109454141 cites W2029930703 @default.
• W2109454141 cites W2034193485 @default.
• W2109454141 cites W2041926007 @default.
• W2109454141 cites W2044892321 @default.
• W2109454141 cites W2048448217 @default.
• W2109454141 cites W2058721535 @default.
• W2109454141 cites W2061338306 @default.
• W2109454141 cites W2066827579 @default.
• W2109454141 cites W2074765204 @default.
• W2109454141 cites W2077697996 @default.
• W2109454141 cites W2101786683 @default.
• W2109454141 cites W2109368213 @default.
• W2109454141 cites W2111211467 @default.
• W2109454141 cites W2112240593 @default.
• W2109454141 cites W2114133992 @default.
• W2109454141 cites W2114250447 @default.
• W2109454141 cites W2118286674 @default.
• W2109454141 cites W2140544891 @default.
• W2109454141 cites W2141157287 @default.
• W2109454141 cites W2141572089 @default.
• W2109454141 cites W2146058063 @default.
• W2109454141 cites W2151230991 @default.
• W2109454141 cites W2152465654 @default.
• W2109454141 cites W2166187656 @default.
• W2109454141 cites W2166603052 @default.
• W2109454141 cites W2166928111 @default.
• W2109454141 cites W2168292723 @default.
• W2109454141 cites W2170525352 @default.
• W2109454141 cites W4210430020 @default.
• W2109454141 cites W4210450218 @default.
• W2109454141 cites W4212865600 @default.
• W2109454141 cites W4236236547 @default.
• W2109454141 doi "https://doi.org/10.1093/bib/bbr038" @default.
• W2109454141 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3178057" @default.
• W2109454141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21712341" @default.
• W2109454141 hasPublicationYear "2011" @default.
• W2109454141 type Work @default.
• W2109454141 sameAs 2109454141 @default.
• W2109454141 citedByCount "11" @default.
• W2109454141 countsByYear W21094541412012 @default.
• W2109454141 countsByYear W21094541412013 @default.
• W2109454141 countsByYear W21094541412014 @default.
• W2109454141 countsByYear W21094541412016 @default.
• W2109454141 countsByYear W21094541412017 @default.
• W2109454141 countsByYear W21094541412018 @default.
• W2109454141 crossrefType "journal-article" @default.
• W2109454141 hasAuthorship W2109454141A5016113894 @default.
• W2109454141 hasAuthorship W2109454141A5041529580 @default.
• W2109454141 hasAuthorship W2109454141A5050068380 @default.
• W2109454141 hasAuthorship W2109454141A5062084820 @default.
• W2109454141 hasAuthorship W2109454141A5063629043 @default.
• W2109454141 hasAuthorship W2109454141A5089205418 @default.
• W2109454141 hasBestOaLocation W21094541411 @default.
• W2109454141 hasConcept C104317684 @default.
• W2109454141 hasConcept C105176652 @default.
• W2109454141 hasConcept C105565629 @default.
• W2109454141 hasConcept C141231307 @default.
• W2109454141 hasConcept C150194340 @default.
• W2109454141 hasConcept C162317418 @default.
• W2109454141 hasConcept C189206191 @default.
• W2109454141 hasConcept C18949551 @default.
• W2109454141 hasConcept C2776321320 @default.
• W2109454141 hasConcept C2908923196 @default.
• W2109454141 hasConcept C51679486 @default.
• W2109454141 hasConcept C54355233 @default.
• W2109454141 hasConcept C70721500 @default.
• W2109454141 hasConcept C79029880 @default.
• W2109454141 hasConcept C86803240 @default.
• W2109454141 hasConcept C89566754 @default.
• W2109454141 hasConceptScore W2109454141C104317684 @default.
• W2109454141 hasConceptScore W2109454141C105176652 @default.
• W2109454141 hasConceptScore W2109454141C105565629 @default.
• W2109454141 hasConceptScore W2109454141C141231307 @default.
• W2109454141 hasConceptScore W2109454141C150194340 @default.
• W2109454141 hasConceptScore W2109454141C162317418 @default.
• W2109454141 hasConceptScore W2109454141C189206191 @default.
• W2109454141 hasConceptScore W2109454141C18949551 @default.
• W2109454141 hasConceptScore W2109454141C2776321320 @default.
• W2109454141 hasConceptScore W2109454141C2908923196 @default.
• W2109454141 hasConceptScore W2109454141C51679486 @default.
• W2109454141 hasConceptScore W2109454141C54355233 @default.

• next