Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109462923> ?p ?o ?g. }
- W2109462923 endingPage "409" @default.
- W2109462923 startingPage "400" @default.
- W2109462923 abstract "It is now clear that two prominent nuclear domains, interchromatin granule clusters (IGCs) and Cajal bodies (CBs), contribute to the highly ordered organization of the extrachromosomal space of the cell nucleus. These functional domains represent structurally stable but highly dynamic nuclear organelles enriched in factors that are required for different nuclear activities, especially RNA biogenesis. IGCs are considered to be the main sites for storage, assembly, and/or recycling of the essential spliceosome components. CBs are involved in the biogenesis of several classes of small RNPs as well as the modification of newly assembled small nuclear RNA. We have summarized data on the molecular composition, structure, and functional roles of IGCs and CBs in the nuclei of mammalian somatic cells and oocytes of some animals with a special focus on insects. We have focused on similarities and differences between the IGCs and CBs of oocytes and the well-studied CBs and IGCs of cultured mammalian somatic cells. We have shown the heterogeneous character of oocyte IGCs and CBs, both in structure and molecular content. We have also demonstrated the unique capacity of oocytes to form close structural interactions between IGC and CB components. We proposed to consider these joint structures as integrated entities, sharing the features of both IGCs and CBs." @default.
- W2109462923 created "2016-06-24" @default.
- W2109462923 creator A5011055575 @default.
- W2109462923 creator A5050746807 @default.
- W2109462923 creator A5059491632 @default.
- W2109462923 date "2009-04-01" @default.
- W2109462923 modified "2023-10-03" @default.
- W2109462923 title "Universal nuclear domains of somatic and germ cells: some lessons from oocyte interchromatin granule cluster and Cajal body structure and molecular composition" @default.
- W2109462923 cites W1481552425 @default.
- W2109462923 cites W1508541438 @default.
- W2109462923 cites W1545138955 @default.
- W2109462923 cites W1549536215 @default.
- W2109462923 cites W1597584782 @default.
- W2109462923 cites W1879996757 @default.
- W2109462923 cites W1904553979 @default.
- W2109462923 cites W1963123022 @default.
- W2109462923 cites W1969097813 @default.
- W2109462923 cites W1969228985 @default.
- W2109462923 cites W1973263622 @default.
- W2109462923 cites W1975210552 @default.
- W2109462923 cites W1975867104 @default.
- W2109462923 cites W1976144441 @default.
- W2109462923 cites W1983811755 @default.
- W2109462923 cites W1984912806 @default.
- W2109462923 cites W1985460296 @default.
- W2109462923 cites W1986675604 @default.
- W2109462923 cites W1986849895 @default.
- W2109462923 cites W1991772727 @default.
- W2109462923 cites W1998976728 @default.
- W2109462923 cites W1999284679 @default.
- W2109462923 cites W2016412991 @default.
- W2109462923 cites W2017305207 @default.
- W2109462923 cites W2017570718 @default.
- W2109462923 cites W2019090030 @default.
- W2109462923 cites W2019731882 @default.
- W2109462923 cites W2020538083 @default.
- W2109462923 cites W2022687073 @default.
- W2109462923 cites W2024839121 @default.
- W2109462923 cites W2024968679 @default.
- W2109462923 cites W2032972166 @default.
- W2109462923 cites W2034339628 @default.
- W2109462923 cites W2037289364 @default.
- W2109462923 cites W2039531548 @default.
- W2109462923 cites W2041159570 @default.
- W2109462923 cites W2042710357 @default.
- W2109462923 cites W2043876975 @default.
- W2109462923 cites W2044827050 @default.
- W2109462923 cites W2045351722 @default.
- W2109462923 cites W2047191306 @default.
- W2109462923 cites W2048251527 @default.
- W2109462923 cites W2051059195 @default.
- W2109462923 cites W2053367204 @default.
- W2109462923 cites W2054544162 @default.
- W2109462923 cites W2054950387 @default.
- W2109462923 cites W2055214710 @default.
- W2109462923 cites W2056202086 @default.
- W2109462923 cites W2057400223 @default.
- W2109462923 cites W2060190448 @default.
- W2109462923 cites W2063501009 @default.
- W2109462923 cites W2063529254 @default.
- W2109462923 cites W2065393106 @default.
- W2109462923 cites W2066438071 @default.
- W2109462923 cites W2069397124 @default.
- W2109462923 cites W2076312344 @default.
- W2109462923 cites W2087908496 @default.
- W2109462923 cites W2091955128 @default.
- W2109462923 cites W2092400927 @default.
- W2109462923 cites W2097627784 @default.
- W2109462923 cites W2098409847 @default.
- W2109462923 cites W2098549100 @default.
- W2109462923 cites W2099856732 @default.
- W2109462923 cites W2101956311 @default.
- W2109462923 cites W2102938475 @default.
- W2109462923 cites W2103250022 @default.
- W2109462923 cites W2105050021 @default.
- W2109462923 cites W2105495356 @default.
- W2109462923 cites W2106102246 @default.
- W2109462923 cites W2107959123 @default.
- W2109462923 cites W2126848848 @default.
- W2109462923 cites W2129709316 @default.
- W2109462923 cites W2138165292 @default.
- W2109462923 cites W2138397691 @default.
- W2109462923 cites W2139979209 @default.
- W2109462923 cites W2140995557 @default.
- W2109462923 cites W2143079500 @default.
- W2109462923 cites W2143854031 @default.
- W2109462923 cites W2148718900 @default.
- W2109462923 cites W2148877698 @default.
- W2109462923 cites W2150361747 @default.
- W2109462923 cites W2151564350 @default.
- W2109462923 cites W2153161471 @default.
- W2109462923 cites W2154658130 @default.
- W2109462923 cites W2155127403 @default.
- W2109462923 cites W2163390689 @default.
- W2109462923 cites W2164297201 @default.
- W2109462923 cites W2166885155 @default.
- W2109462923 cites W2167331686 @default.
- W2109462923 cites W8936523 @default.