FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109463380> ?p ?o ?g. }

• W2109463380 endingPage "1479" @default.
• W2109463380 startingPage "1468" @default.
• W2109463380 abstract "The influence of the transcriptional enhancer of the pea plastocyanin gene (PetE) on the acetylation of histones was examined with chromatin immunoprecipitation (ChIP) experiments using antibodies that recognize acetylated or nonacetylated histones H3 and H4. In transgenic tobacco plants containing the pea PetE promoter fused to uidA, both acetylated and nonacetylated histones H3 and H4 were present on the integrated transgene. Linking the PetE enhancer to the transgene resulted in increased beta-glucuronidase activity and increased amounts of acetylated histones H3 and H4 present on the promoter, suggesting that the enhancer may increase transcription by mediating the acetylation of histones. Trichostatin A and sodium butyrate, which are potent inhibitors of histone deacetylases (HDAs), activated expression from the PetE promoter by fourfold, with a concomitant increase in the acetylation states of histones H3 and H4, as determined by ChIP, indicating that the acetylation of histones has a direct positive effect on transcription. The HDA inhibitors did not increase expression from the PetE promoter when it was linked to the enhancer, consistent with preexisting hyperacetylated histones on the transgene. Mapping of histone acetylation states along the reporter gene indicated that the histones H3 and H4 associated with the promoter and the 5' region of uidA were hyperacetylated in the presence of the PetE enhancer. The PetE enhancer bound to isolated tobacco nuclear matrices in vitro and was associated with the nuclear matrix in nuclei isolated from transgenic tobacco plants. These results suggest that the pea PetE enhancer activates transcription by associating with the nuclear matrix, mediating the acetylation of histones on the promoter and the nearby coding region and resulting in an altered chromatin structure." @default.
• W2109463380 created "2016-06-24" @default.
• W2109463380 creator A5017727391 @default.
• W2109463380 creator A5064905910 @default.
• W2109463380 creator A5072775386 @default.
• W2109463380 date "2003-05-16" @default.
• W2109463380 modified "2023-10-15" @default.
• W2109463380 title "The Transcriptional Enhancer of the Pea Plastocyanin Gene Associates with the Nuclear Matrix and Regulates Gene Expression through Histone Acetylation" @default.
• W2109463380 cites W1539503448 @default.
• W2109463380 cites W1552353351 @default.
• W2109463380 cites W1555196747 @default.
• W2109463380 cites W1556668723 @default.
• W2109463380 cites W1563624749 @default.
• W2109463380 cites W1606632025 @default.
• W2109463380 cites W1634746048 @default.
• W2109463380 cites W1874881634 @default.
• W2109463380 cites W1933411091 @default.
• W2109463380 cites W1969770714 @default.
• W2109463380 cites W1970139633 @default.
• W2109463380 cites W1971792543 @default.
• W2109463380 cites W1983287256 @default.
• W2109463380 cites W2002698073 @default.
• W2109463380 cites W2004215286 @default.
• W2109463380 cites W2010920942 @default.
• W2109463380 cites W2016236490 @default.
• W2109463380 cites W2017311565 @default.
• W2109463380 cites W2018289835 @default.
• W2109463380 cites W2018966815 @default.
• W2109463380 cites W2019072238 @default.
• W2109463380 cites W2019155756 @default.
• W2109463380 cites W2022051395 @default.
• W2109463380 cites W2023505637 @default.
• W2109463380 cites W2025909991 @default.
• W2109463380 cites W2034146467 @default.
• W2109463380 cites W2037108809 @default.
• W2109463380 cites W2037539600 @default.
• W2109463380 cites W2041803958 @default.
• W2109463380 cites W2043734426 @default.
• W2109463380 cites W2057363045 @default.
• W2109463380 cites W2062438194 @default.
• W2109463380 cites W2065721092 @default.
• W2109463380 cites W2076446466 @default.
• W2109463380 cites W2084063692 @default.
• W2109463380 cites W2088512514 @default.
• W2109463380 cites W2090635946 @default.
• W2109463380 cites W2098566952 @default.
• W2109463380 cites W2100837269 @default.
• W2109463380 cites W2110432853 @default.
• W2109463380 cites W2123416293 @default.
• W2109463380 cites W2125388973 @default.
• W2109463380 cites W2125852599 @default.
• W2109463380 cites W2128738669 @default.
• W2109463380 cites W2135404694 @default.
• W2109463380 cites W2135522516 @default.
• W2109463380 cites W2135858450 @default.
• W2109463380 cites W2153833981 @default.
• W2109463380 cites W2158490353 @default.
• W2109463380 cites W2159228126 @default.
• W2109463380 cites W2160646902 @default.
• W2109463380 cites W2161939161 @default.
• W2109463380 cites W2162990030 @default.
• W2109463380 cites W2163046373 @default.
• W2109463380 cites W2165308495 @default.
• W2109463380 cites W2165867989 @default.
• W2109463380 cites W2166137396 @default.
• W2109463380 cites W2167517334 @default.
• W2109463380 cites W2171055843 @default.
• W2109463380 doi "https://doi.org/10.1105/tpc.011825" @default.
• W2109463380 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/156380" @default.
• W2109463380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12782737" @default.
• W2109463380 hasPublicationYear "2003" @default.
• W2109463380 type Work @default.
• W2109463380 sameAs 2109463380 @default.
• W2109463380 citedByCount "101" @default.
• W2109463380 countsByYear W21094633802012 @default.
• W2109463380 countsByYear W21094633802013 @default.
• W2109463380 countsByYear W21094633802014 @default.
• W2109463380 countsByYear W21094633802015 @default.
• W2109463380 countsByYear W21094633802016 @default.
• W2109463380 countsByYear W21094633802017 @default.
• W2109463380 countsByYear W21094633802018 @default.
• W2109463380 countsByYear W21094633802019 @default.
• W2109463380 countsByYear W21094633802020 @default.
• W2109463380 countsByYear W21094633802021 @default.
• W2109463380 countsByYear W21094633802022 @default.
• W2109463380 countsByYear W21094633802023 @default.
• W2109463380 crossrefType "journal-article" @default.
• W2109463380 hasAuthorship W2109463380A5017727391 @default.
• W2109463380 hasAuthorship W2109463380A5064905910 @default.
• W2109463380 hasAuthorship W2109463380A5072775386 @default.
• W2109463380 hasBestOaLocation W21094633801 @default.
• W2109463380 hasConcept C101762097 @default.
• W2109463380 hasConcept C102230213 @default.
• W2109463380 hasConcept C104317684 @default.
• W2109463380 hasConcept C111936080 @default.
• W2109463380 hasConcept C119157956 @default.
• W2109463380 hasConcept C134320426 @default.
• W2109463380 hasConcept C150194340 @default.

• next