Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109478664> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2109478664 endingPage "127" @default.
- W2109478664 startingPage "124" @default.
- W2109478664 abstract "Introduction – Swainsonine, a polyhydroxy indolizidine alkaloid and known glycosidase inhibitor, is found in a number of different plants that cause a lysosomal storage disease known as locoism in the western USA. Most recently swainsonine has been analysed by LC-MS/MS after sample extraction and preparation from ion-exchange resins. Objective – To compare previously published sample preparation procedures with several new alternative procedures to provide methods using either commercially available solid-phase extraction equipment or procedures which significantly reduce sample preparation time. Methodology – A previously reported and validated sample preparation method using ion-exchange resin was compared with methods using a commercially available solid-phase extraction cartridge, a solvent partitioning procedure or a single solvent extraction procedure using one of two solvents. Twenty different plant samples of varying swainsonine concentrations were prepared in triplicate and analysed by LC-MS/MS. The measured concentration of swainsonine was then statistically compared between methods. Results – There were no statistically significant differences found between four of the five different sample preparation methods tested. Conclusion – A commercially available SPE cartridge can be used to replace the previously used ion-exchange resin for swainsonine analysis. For very rapid analyses the SPE procedure can be eliminated and a simple, single solvent extraction step used for sample preparation. Published in 2010 by John Wiley & Sons, Ltd." @default.
- W2109478664 created "2016-06-24" @default.
- W2109478664 creator A5049934298 @default.
- W2109478664 creator A5055878838 @default.
- W2109478664 date "2010-08-26" @default.
- W2109478664 modified "2023-10-07" @default.
- W2109478664 title "A comparison of alternative sample preparation procedures for the analysis of swainsonine using LC-MS/MS" @default.
- W2109478664 cites W1965355928 @default.
- W2109478664 cites W1993473871 @default.
- W2109478664 cites W2004160096 @default.
- W2109478664 cites W2012959468 @default.
- W2109478664 cites W2053714061 @default.
- W2109478664 cites W2066002401 @default.
- W2109478664 cites W2070917067 @default.
- W2109478664 cites W57809147 @default.
- W2109478664 doi "https://doi.org/10.1002/pca.1257" @default.
- W2109478664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20799276" @default.
- W2109478664 hasPublicationYear "2010" @default.
- W2109478664 type Work @default.
- W2109478664 sameAs 2109478664 @default.
- W2109478664 citedByCount "38" @default.
- W2109478664 countsByYear W21094786642012 @default.
- W2109478664 countsByYear W21094786642013 @default.
- W2109478664 countsByYear W21094786642014 @default.
- W2109478664 countsByYear W21094786642015 @default.
- W2109478664 countsByYear W21094786642016 @default.
- W2109478664 countsByYear W21094786642017 @default.
- W2109478664 countsByYear W21094786642018 @default.
- W2109478664 countsByYear W21094786642019 @default.
- W2109478664 countsByYear W21094786642021 @default.
- W2109478664 countsByYear W21094786642022 @default.
- W2109478664 crossrefType "journal-article" @default.
- W2109478664 hasAuthorship W2109478664A5049934298 @default.
- W2109478664 hasAuthorship W2109478664A5055878838 @default.
- W2109478664 hasConcept C127413603 @default.
- W2109478664 hasConcept C162356407 @default.
- W2109478664 hasConcept C175467004 @default.
- W2109478664 hasConcept C178790620 @default.
- W2109478664 hasConcept C185592680 @default.
- W2109478664 hasConcept C2775928797 @default.
- W2109478664 hasConcept C2777667214 @default.
- W2109478664 hasConcept C2778576202 @default.
- W2109478664 hasConcept C2779768532 @default.
- W2109478664 hasConcept C2780471494 @default.
- W2109478664 hasConcept C2992805683 @default.
- W2109478664 hasConcept C34381374 @default.
- W2109478664 hasConcept C43617362 @default.
- W2109478664 hasConcept C4725764 @default.
- W2109478664 hasConcept C64489805 @default.
- W2109478664 hasConcept C73523448 @default.
- W2109478664 hasConcept C78519656 @default.
- W2109478664 hasConcept C81426234 @default.
- W2109478664 hasConceptScore W2109478664C127413603 @default.
- W2109478664 hasConceptScore W2109478664C162356407 @default.
- W2109478664 hasConceptScore W2109478664C175467004 @default.
- W2109478664 hasConceptScore W2109478664C178790620 @default.
- W2109478664 hasConceptScore W2109478664C185592680 @default.
- W2109478664 hasConceptScore W2109478664C2775928797 @default.
- W2109478664 hasConceptScore W2109478664C2777667214 @default.
- W2109478664 hasConceptScore W2109478664C2778576202 @default.
- W2109478664 hasConceptScore W2109478664C2779768532 @default.
- W2109478664 hasConceptScore W2109478664C2780471494 @default.
- W2109478664 hasConceptScore W2109478664C2992805683 @default.
- W2109478664 hasConceptScore W2109478664C34381374 @default.
- W2109478664 hasConceptScore W2109478664C43617362 @default.
- W2109478664 hasConceptScore W2109478664C4725764 @default.
- W2109478664 hasConceptScore W2109478664C64489805 @default.
- W2109478664 hasConceptScore W2109478664C73523448 @default.
- W2109478664 hasConceptScore W2109478664C78519656 @default.
- W2109478664 hasConceptScore W2109478664C81426234 @default.
- W2109478664 hasIssue "2" @default.
- W2109478664 hasLocation W21094786641 @default.
- W2109478664 hasLocation W21094786642 @default.
- W2109478664 hasOpenAccess W2109478664 @default.
- W2109478664 hasPrimaryLocation W21094786641 @default.
- W2109478664 hasRelatedWork W1987582664 @default.
- W2109478664 hasRelatedWork W1989646464 @default.
- W2109478664 hasRelatedWork W2022746501 @default.
- W2109478664 hasRelatedWork W2109478664 @default.
- W2109478664 hasRelatedWork W2382631793 @default.
- W2109478664 hasRelatedWork W2950850180 @default.
- W2109478664 hasRelatedWork W2952641266 @default.
- W2109478664 hasRelatedWork W3013313226 @default.
- W2109478664 hasRelatedWork W4241680375 @default.
- W2109478664 hasRelatedWork W57809147 @default.
- W2109478664 hasVolume "22" @default.
- W2109478664 isParatext "false" @default.
- W2109478664 isRetracted "false" @default.
- W2109478664 magId "2109478664" @default.
- W2109478664 workType "article" @default.