Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109490022> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2109490022 endingPage "247" @default.
- W2109490022 startingPage "239" @default.
- W2109490022 abstract "A process model for the enzymatic synthesis of (R)-cyanohydrins in an aqueous-organic biphasic-stirred tank reactor was developed. The conversion of benzal-dehyde into (R)-mandelonitrile, catalyzed by Prunus amygdalus hydroxynitrile lyase at 5 degrees C and pH 5.5, was chosen as a model system with methyl tert-butyl ether as the organic phase. The process model consisted of a description of the reaction kinetics, mass transfer kinetics, and the mass balances for both the aqueous and the organic phase. Values for the enzyme kinetic parameters, according to ordered bi-uni kinetics, the lumped mass transfer coefficient for benzaldehyde, and the partition coefficients were determined separately. The process model is validated by using 11 experimental data sets of batch conversions in the aqueous-organic biphasic-stirred tank reactor. In these 11 experiments, different enzyme concentrations and phase volume ratios were used. The model was found to be valid with respect to both the conversion and the enantiomeric excess. To synthesize cyanohydrins with a high enantiomeric excess, the enzyme is required to work at mass transfer limited conditions. The developed process model will be used to investigate other process concepts and other substrates." @default.
- W2109490022 created "2016-06-24" @default.
- W2109490022 creator A5020363983 @default.
- W2109490022 creator A5020751751 @default.
- W2109490022 creator A5035234231 @default.
- W2109490022 creator A5041647569 @default.
- W2109490022 creator A5059482510 @default.
- W2109490022 creator A5076010654 @default.
- W2109490022 creator A5090214575 @default.
- W2109490022 date "2001-12-17" @default.
- W2109490022 modified "2023-10-10" @default.
- W2109490022 title "Development of a process model to describe the synthesis of (R)-mandelonitrile byPrunus amygdalus hydroxynitrile lyase in an aqueous-organic biphasic reactor" @default.
- W2109490022 cites W1994799266 @default.
- W2109490022 cites W1995963602 @default.
- W2109490022 cites W2000198661 @default.
- W2109490022 cites W2011203173 @default.
- W2109490022 cites W2014386639 @default.
- W2109490022 cites W2021388735 @default.
- W2109490022 cites W2032655783 @default.
- W2109490022 cites W2047317230 @default.
- W2109490022 cites W2052704730 @default.
- W2109490022 cites W2065880092 @default.
- W2109490022 cites W2087374129 @default.
- W2109490022 cites W2117018776 @default.
- W2109490022 cites W2144061685 @default.
- W2109490022 cites W2157397846 @default.
- W2109490022 cites W2949100716 @default.
- W2109490022 doi "https://doi.org/10.1002/bit.10002" @default.
- W2109490022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11753932" @default.
- W2109490022 hasPublicationYear "2001" @default.
- W2109490022 type Work @default.
- W2109490022 sameAs 2109490022 @default.
- W2109490022 citedByCount "29" @default.
- W2109490022 countsByYear W21094900222012 @default.
- W2109490022 countsByYear W21094900222015 @default.
- W2109490022 countsByYear W21094900222017 @default.
- W2109490022 countsByYear W21094900222020 @default.
- W2109490022 countsByYear W21094900222021 @default.
- W2109490022 countsByYear W21094900222022 @default.
- W2109490022 crossrefType "journal-article" @default.
- W2109490022 hasAuthorship W2109490022A5020363983 @default.
- W2109490022 hasAuthorship W2109490022A5020751751 @default.
- W2109490022 hasAuthorship W2109490022A5035234231 @default.
- W2109490022 hasAuthorship W2109490022A5041647569 @default.
- W2109490022 hasAuthorship W2109490022A5059482510 @default.
- W2109490022 hasAuthorship W2109490022A5076010654 @default.
- W2109490022 hasAuthorship W2109490022A5090214575 @default.
- W2109490022 hasConcept C121332964 @default.
- W2109490022 hasConcept C148898269 @default.
- W2109490022 hasConcept C149556010 @default.
- W2109490022 hasConcept C161790260 @default.
- W2109490022 hasConcept C178790620 @default.
- W2109490022 hasConcept C184651966 @default.
- W2109490022 hasConcept C185592680 @default.
- W2109490022 hasConcept C2779692420 @default.
- W2109490022 hasConcept C43617362 @default.
- W2109490022 hasConcept C47502133 @default.
- W2109490022 hasConcept C486523 @default.
- W2109490022 hasConcept C51038369 @default.
- W2109490022 hasConcept C62520636 @default.
- W2109490022 hasConceptScore W2109490022C121332964 @default.
- W2109490022 hasConceptScore W2109490022C148898269 @default.
- W2109490022 hasConceptScore W2109490022C149556010 @default.
- W2109490022 hasConceptScore W2109490022C161790260 @default.
- W2109490022 hasConceptScore W2109490022C178790620 @default.
- W2109490022 hasConceptScore W2109490022C184651966 @default.
- W2109490022 hasConceptScore W2109490022C185592680 @default.
- W2109490022 hasConceptScore W2109490022C2779692420 @default.
- W2109490022 hasConceptScore W2109490022C43617362 @default.
- W2109490022 hasConceptScore W2109490022C47502133 @default.
- W2109490022 hasConceptScore W2109490022C486523 @default.
- W2109490022 hasConceptScore W2109490022C51038369 @default.
- W2109490022 hasConceptScore W2109490022C62520636 @default.
- W2109490022 hasIssue "3" @default.
- W2109490022 hasLocation W21094900221 @default.
- W2109490022 hasLocation W21094900222 @default.
- W2109490022 hasOpenAccess W2109490022 @default.
- W2109490022 hasPrimaryLocation W21094900221 @default.
- W2109490022 hasRelatedWork W1533372989 @default.
- W2109490022 hasRelatedWork W1969295444 @default.
- W2109490022 hasRelatedWork W2029895066 @default.
- W2109490022 hasRelatedWork W2047324127 @default.
- W2109490022 hasRelatedWork W2362801003 @default.
- W2109490022 hasRelatedWork W2366650074 @default.
- W2109490022 hasRelatedWork W2371017285 @default.
- W2109490022 hasRelatedWork W2413936414 @default.
- W2109490022 hasRelatedWork W2581564447 @default.
- W2109490022 hasRelatedWork W4319263624 @default.
- W2109490022 hasVolume "77" @default.
- W2109490022 isParatext "false" @default.
- W2109490022 isRetracted "false" @default.
- W2109490022 magId "2109490022" @default.
- W2109490022 workType "article" @default.