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• W2109490045 startingPage "3937" @default.
• W2109490045 abstract "An ectopic recombination system using ura3 heteroalleles varying in size from 80 to 960 bp has been used to examine the effect of substrate length on spontaneous mitotic recombination. The ura3 heteroalleles were positioned either on nonhomologous chromosomes (heterochromosomal repeats) or as direct or inverted repeats on the same chromosome (intrachromosomal repeats). While the intrachromosomal events occur at rates at least 2 orders of magnitude greater than the corresponding heterochromosomal events, the recombination rate for each type of repeat considered separately exhibits a linear dependence on substrate length. The linear relationships allow estimation of the corresponding minimal efficient processing segments, which are approximately 250 bp regardless of the relative positions of the repeats in the yeast genome. An examination of the distribution of recombination events into simple gene conversion versus crossover events indicates that reciprocal exchange is more sensitive to substrate size than is gene conversion." @default.
• W2109490045 created "2016-06-24" @default.
• W2109490045 creator A5006009524 @default.
• W2109490045 creator A5034804756 @default.
• W2109490045 creator A5075731872 @default.
• W2109490045 date "1993-07-01" @default.
• W2109490045 modified "2023-09-27" @default.
• W2109490045 title "Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae" @default.
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• W2109490045 doi "https://doi.org/10.1128/mcb.13.7.3937-3950.1993" @default.
• W2109490045 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/359934" @default.
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