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- W2109565332 abstract "The proteasome is a multicatalytic protease complex whose activity is required for the growth of normal or tumor cells. It has been shown that human cancer cells are more sensitive to proteasome inhibition than normal cells, indicating that the proteasome could be a target of chemotherapy. Studies suggest that traditional Chinese medicine (TCM) is an effective approach for cancer treatment. Here we reviewed several TCMs for their potential in treatment of cancer. This short review focuses mainly on the TCMs that potentially target the tumor cellular proteasome and NF-κB pathway whose activation is dependent on the proteasome activity. Keywords: Proteasome inhibitors, natural products, medicinal compounds, cancer, prevention, treatment" @default.
- W2109565332 created "2016-06-24" @default.
- W2109565332 creator A5028928025 @default.
- W2109565332 creator A5031517911 @default.
- W2109565332 creator A5051071198 @default.
- W2109565332 date "2010-03-01" @default.
- W2109565332 modified "2023-09-25" @default.
- W2109565332 title "Targeting Tumor Proteasome with Traditional Chinese Medicine" @default.
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- W2109565332 doi "https://doi.org/10.2174/157016310791162785" @default.
- W2109565332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3306007" @default.
- W2109565332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20156140" @default.
- W2109565332 hasPublicationYear "2010" @default.
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