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• W2109579942 startingPage "1361" @default.
• W2109579942 abstract "To understand how gene expression patterns are established on the inactive X chromosome during development, we have studied the murine gene Smcx, which is expressed from both the active and inactive mouse X chromosomes. In all tissues assayed, Smcx only partially escapes X inactivation, with expression levels from the inactive X allele ∼30–65% that of the active X allele. Additionally, inactive X expression levels differed between extraembryonic and embryonic tissues and among different tissues from newborn and adult mice. Imprinted extraembryonic tissue had the lowest levels of inactive X Smcx expression, whereas the highest levels were in heart. These data suggest that the chromosomal basis of X inactivation differs among tissues, perhaps reflecting differences in the timing or regulation of inactivation in these cell lineages." @default.
• W2109579942 created "2016-06-24" @default.
• W2109579942 creator A5086070874 @default.
• W2109579942 date "1996-09-01" @default.
• W2109579942 modified "2023-09-27" @default.
• W2109579942 title "Tissue and lineage-specific variation in inactive X chromosome expression of the murine Smcx gene" @default.
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• W2109579942 doi "https://doi.org/10.1093/hmg/5.9.1361" @default.
• W2109579942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8872478" @default.
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