Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109615104> ?p ?o ?g. }
- W2109615104 endingPage "1829" @default.
- W2109615104 startingPage "1802" @default.
- W2109615104 abstract "Arenaviruses are enveloped, bipartite negative single-stranded RNA viruses that can cause a wide spectrum of disease in humans and experimental animals including hemorrhagic fever. The majority of these viruses are rodent-borne and the arenavirus family can be divided into two groups: the Lassa-Lymphocytic choriomeningitis serocomplex and the Tacaribe serocomplex. Arenavirus-induced disease may include characteristic symptoms ranging from fever, malaise, body aches, petechiae, dehydration, hemorrhage, organ failure, shock, and in severe cases death. Currently, there are few prophylactic and therapeutic treatments available for arenavirus-induced symptoms. Supportive care and ribavirin remain the predominant strategies for treating most of the arenavirus-induced diseases. Therefore, efficacy testing of novel therapeutic and prophylactic strategies in relevant animal models is necessary. Because of the potential for person-to-person spread, the ability to cause lethal or debilitating disease in humans, limited treatment options, and potential as a bio-weapon, the development of prophylactics and therapeutics is essential. This article reviews the current arenavirus animal models and prophylactic and therapeutic strategies under development to treat arenavirus infection." @default.
- W2109615104 created "2016-06-24" @default.
- W2109615104 creator A5023323394 @default.
- W2109615104 date "2012-09-24" @default.
- W2109615104 modified "2023-10-13" @default.
- W2109615104 title "Animal Models, Prophylaxis, and Therapeutics for Arenavirus Infections" @default.
- W2109615104 cites W1252554981 @default.
- W2109615104 cites W146626956 @default.
- W2109615104 cites W1543288877 @default.
- W2109615104 cites W1557552990 @default.
- W2109615104 cites W1656644300 @default.
- W2109615104 cites W1900155367 @default.
- W2109615104 cites W1924452530 @default.
- W2109615104 cites W1939567899 @default.
- W2109615104 cites W1966482228 @default.
- W2109615104 cites W1967066470 @default.
- W2109615104 cites W1972859660 @default.
- W2109615104 cites W1974624739 @default.
- W2109615104 cites W1981428942 @default.
- W2109615104 cites W1984834692 @default.
- W2109615104 cites W1996938063 @default.
- W2109615104 cites W2001653092 @default.
- W2109615104 cites W2008110867 @default.
- W2109615104 cites W2016436352 @default.
- W2109615104 cites W2034508297 @default.
- W2109615104 cites W2035537148 @default.
- W2109615104 cites W2035572149 @default.
- W2109615104 cites W2036374965 @default.
- W2109615104 cites W2039941020 @default.
- W2109615104 cites W2041851359 @default.
- W2109615104 cites W2046305528 @default.
- W2109615104 cites W2046547573 @default.
- W2109615104 cites W2050499473 @default.
- W2109615104 cites W2050600395 @default.
- W2109615104 cites W2058150819 @default.
- W2109615104 cites W2065825017 @default.
- W2109615104 cites W2070792333 @default.
- W2109615104 cites W2077564249 @default.
- W2109615104 cites W2081551292 @default.
- W2109615104 cites W2082214627 @default.
- W2109615104 cites W2083556261 @default.
- W2109615104 cites W2091785636 @default.
- W2109615104 cites W2092905078 @default.
- W2109615104 cites W2094071702 @default.
- W2109615104 cites W2095257178 @default.
- W2109615104 cites W2100910315 @default.
- W2109615104 cites W2108367829 @default.
- W2109615104 cites W2109414153 @default.
- W2109615104 cites W2110651173 @default.
- W2109615104 cites W2116816109 @default.
- W2109615104 cites W2116887577 @default.
- W2109615104 cites W2121251963 @default.
- W2109615104 cites W2121935682 @default.
- W2109615104 cites W2123710681 @default.
- W2109615104 cites W2125370793 @default.
- W2109615104 cites W2130276289 @default.
- W2109615104 cites W2136068495 @default.
- W2109615104 cites W2136901298 @default.
- W2109615104 cites W2137775515 @default.
- W2109615104 cites W2138274210 @default.
- W2109615104 cites W2138694080 @default.
- W2109615104 cites W2138992015 @default.
- W2109615104 cites W2139253965 @default.
- W2109615104 cites W2139718518 @default.
- W2109615104 cites W2145641356 @default.
- W2109615104 cites W2152624614 @default.
- W2109615104 cites W2153568159 @default.
- W2109615104 cites W2157678105 @default.
- W2109615104 cites W2157888892 @default.
- W2109615104 cites W2161965179 @default.
- W2109615104 cites W2166870193 @default.
- W2109615104 cites W2171893677 @default.
- W2109615104 cites W2182721755 @default.
- W2109615104 cites W2203700471 @default.
- W2109615104 cites W2294686441 @default.
- W2109615104 cites W2346590988 @default.
- W2109615104 cites W2396006285 @default.
- W2109615104 cites W2396133667 @default.
- W2109615104 cites W2463543302 @default.
- W2109615104 cites W2802386465 @default.
- W2109615104 cites W4236672674 @default.
- W2109615104 cites W55028985 @default.
- W2109615104 cites W59884710 @default.
- W2109615104 cites W6374058 @default.
- W2109615104 cites W2170355891 @default.
- W2109615104 doi "https://doi.org/10.3390/v4091802" @default.
- W2109615104 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3499831" @default.
- W2109615104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23170184" @default.
- W2109615104 hasPublicationYear "2012" @default.
- W2109615104 type Work @default.
- W2109615104 sameAs 2109615104 @default.
- W2109615104 citedByCount "37" @default.
- W2109615104 countsByYear W21096151042013 @default.
- W2109615104 countsByYear W21096151042014 @default.
- W2109615104 countsByYear W21096151042015 @default.
- W2109615104 countsByYear W21096151042016 @default.
- W2109615104 countsByYear W21096151042017 @default.
- W2109615104 countsByYear W21096151042018 @default.