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- W2109647574 abstract "The component reactions of the hexose monophosphate oxidative pathway have been studied in adult houseflies. It has been shown that houseflies possess an active glucose-6-phosphate dehydrogenase, 6-phosphogluconolactonase, 6-phosphogluconic dehydrogenase, phosphopentose isomerase, phosphoketopentose epimerase, transketolase, and transaldolase.The cycle consists of five main steps: (a) a two-step oxidation of glucose-6-phosphate to ribulose-5-phosphate and CO 2 ; (b) isomerization of ribulose-5-phosphate to ribose-5-phosphate; (c) epimerization of ribulose-5-phosphate to xylulose-5-phosphate; (d) conversion of pentose phosphate to sedoheptulose phosphate and triose phosphate; (e) conversion of sedoheptulose phosphate to hexose phosphate.Balance studies indicate that 2 moles of pentose phosphate are utilized for the formation of 1 mole of heptulose phosphate. However, this stoichiometry is attained after a lag period, suggesting the formation of a transient intermediate. Because the lag was eliminated by the addition of hydroxypyruvate, it is suggested that the lag was due to the time required for the combination of a C 2 fragment with an appropriate aldehyde acceptor." @default.
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- W2109647574 date "1958-01-01" @default.
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- W2109647574 title "OXIDATIVE METABOLISM OF CARBOHYDRATES IN INSECTS: III. HEXOSE MONOPHOSPHATE OXIDATIVE CYCLE IN THE HOUSEFLY, MUSCA DOMESTICA L." @default.
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- W2109647574 doi "https://doi.org/10.1139/y58-012" @default.
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