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• W2109649945 abstract "The effects of contamination, through water or food, of a sublethal dose of the organophosphate methyl parathion were analyzed in tissues that are responsible for absorption (gills, intestine) and metabolism (liver), in the freshwater fish Corydoras paleatus. In gill respiratory lamellae, epithelial hyperplasia, edema, and detachment occurred, diminishing sooner after contamination by food than after contamination through water. In the intestine, lipoid vacuolization of enterocytes, apical cytoplasm, and an increase in goblet cell activity occurred mainly after ingestion of contaminated food. The liver exhibited cloudy swelling, bile stagnation, focal necrosis, atrophy, and vacuolization after contamination through both absorption routes, the highest degeneration being between T8 and T24. Metabolic processes that depend on liver function were equally impaired by the two routes of contamination, but secondary effects vary with gill and intestine pathologies as a consequence of water and food contamination, respectively. Therefore, a “safe” sublethal dose of methyl parathion causes serious health problems in C. paleatus." @default.
• W2109649945 created "2016-06-24" @default.
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• W2109649945 date "2003-02-01" @default.
• W2109649945 modified "2023-09-30" @default.
• W2109649945 title "Histopathology of the fish Corydoras paleatus contaminated with sublethal levels of organophosphorus in water and food" @default.
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• W2109649945 doi "https://doi.org/10.1016/s0147-6513(02)00044-1" @default.
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