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- W2109664513 abstract "We congratulate Milara et al 1 for getting a paper suggesting that epithelial mesenchymal transition (EMT) is important in the pathogenesis of chronic obstructive pulmonary disease (COPD) into a top respiratory journal. This is quite a breakthrough.In the discussion, Milara et al were somewhat dismissive of our findings on EMT markers in large airways of COPD patients;2 commenting that our study was limited by the mesenchymal protein expressions analysed (MMP-9, S100A4, vimentin) being potentially expressed by inflammatory cells. In a follow-up paper3 we excluded such confounding. Further, our study illustrated that cells in the basal epithelium, and reticular basement membrane (Rbm) in smokers/COPD double-stain for cytokeratin-(s) and the ‘EMT marker’ S100A4, confirming a likely epithelial …" @default.
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- W2109664513 date "2013-03-14" @default.
- W2109664513 modified "2023-09-27" @default.
- W2109664513 title "Epithelial mesenchymal transition (EMT) in small airways of COPD patients" @default.
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- W2109664513 doi "https://doi.org/10.1136/thoraxjnl-2013-203373" @default.
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