FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109722019> ?p ?o ?g. }

• W2109722019 endingPage "1853" @default.
• W2109722019 startingPage "1844" @default.
• W2109722019 abstract "Summary Objectives Anterior temporal lobectomy is curative for many patients with disabling medically refractory temporal lobe epilepsy, but carries an inherent risk of disabling verbal memory loss. Although accurate prediction of iatrogenic memory loss is becoming increasingly possible, it remains unclear how much weight such predictions should have in surgical decision making. Here we aim to create a framework that facilitates a systematic and integrated assessment of the relative risks and benefits of surgery versus medical management for patients with left temporal lobe epilepsy. Methods We constructed a Markov decision model to evaluate the probabilistic outcomes and associated health utilities associated with choosing to undergo a left anterior temporal lobectomy versus continuing with medical management for patients with medically refractory left temporal lobe epilepsy. Three base‐cases were considered, representing a spectrum of surgical candidates encountered in practice, with varying degrees of epilepsy‐related disability and potential for decreased quality of life in response to post‐surgical verbal memory deficits. Results For patients with moderately severe seizures and moderate risk of verbal memory loss, medical management was the preferred decision, with increased quality‐adjusted life expectancy. However, the preferred choice was sensitive to clinically meaningful changes in several parameters, including quality of life impact of verbal memory decline, quality of life with seizures, mortality rate with medical management, probability of remission following surgery, and probability of remission with medical management. Significance Our decision model suggests that for patients with left temporal lobe epilepsy, quantitative assessment of risk and benefit should guide recommendation of therapy. In particular, risk for and potential impact of verbal memory decline should be carefully weighed against the degree of disability conferred by continued seizures on a patient‐by‐patient basis." @default.
• W2109722019 created "2016-06-24" @default.
• W2109722019 creator A5023557669 @default.
• W2109722019 creator A5031778533 @default.
• W2109722019 creator A5046780689 @default.
• W2109722019 creator A5065493403 @default.
• W2109722019 creator A5077601092 @default.
• W2109722019 creator A5080172074 @default.
• W2109722019 date "2014-09-19" @default.
• W2109722019 modified "2023-10-05" @default.
• W2109722019 title "Weighing the value of memory loss in the surgical evaluation of left temporal lobe epilepsy: A decision analysis" @default.
• W2109722019 cites W1524208329 @default.
• W2109722019 cites W1965841995 @default.
• W2109722019 cites W1966749913 @default.
• W2109722019 cites W1967272280 @default.
• W2109722019 cites W1972575115 @default.
• W2109722019 cites W1972575666 @default.
• W2109722019 cites W1976965104 @default.
• W2109722019 cites W1979808630 @default.
• W2109722019 cites W1987584839 @default.
• W2109722019 cites W1991755871 @default.
• W2109722019 cites W2000086948 @default.
• W2109722019 cites W2011926671 @default.
• W2109722019 cites W2021074267 @default.
• W2109722019 cites W2029036450 @default.
• W2109722019 cites W2031205938 @default.
• W2109722019 cites W2032947105 @default.
• W2109722019 cites W2040607890 @default.
• W2109722019 cites W2042291251 @default.
• W2109722019 cites W2058754478 @default.
• W2109722019 cites W2063397439 @default.
• W2109722019 cites W2066157763 @default.
• W2109722019 cites W2071821162 @default.
• W2109722019 cites W2079758805 @default.
• W2109722019 cites W2082471359 @default.
• W2109722019 cites W2083108806 @default.
• W2109722019 cites W2086132039 @default.
• W2109722019 cites W2086219346 @default.
• W2109722019 cites W2087831750 @default.
• W2109722019 cites W2096695182 @default.
• W2109722019 cites W2097960231 @default.
• W2109722019 cites W2098706009 @default.
• W2109722019 cites W2100411562 @default.
• W2109722019 cites W2117378831 @default.
• W2109722019 cites W2122817080 @default.
• W2109722019 cites W2147744475 @default.
• W2109722019 cites W2150899657 @default.
• W2109722019 cites W2161524679 @default.
• W2109722019 cites W2317495993 @default.
• W2109722019 doi "https://doi.org/10.1111/epi.12790" @default.
• W2109722019 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4877127" @default.
• W2109722019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25244498" @default.
• W2109722019 hasPublicationYear "2014" @default.
• W2109722019 type Work @default.
• W2109722019 sameAs 2109722019 @default.
• W2109722019 citedByCount "11" @default.
• W2109722019 countsByYear W21097220192015 @default.
• W2109722019 countsByYear W21097220192016 @default.
• W2109722019 countsByYear W21097220192017 @default.
• W2109722019 countsByYear W21097220192018 @default.
• W2109722019 countsByYear W21097220192020 @default.
• W2109722019 countsByYear W21097220192022 @default.
• W2109722019 countsByYear W21097220192023 @default.
• W2109722019 crossrefType "journal-article" @default.
• W2109722019 hasAuthorship W2109722019A5023557669 @default.
• W2109722019 hasAuthorship W2109722019A5031778533 @default.
• W2109722019 hasAuthorship W2109722019A5046780689 @default.
• W2109722019 hasAuthorship W2109722019A5065493403 @default.
• W2109722019 hasAuthorship W2109722019A5077601092 @default.
• W2109722019 hasAuthorship W2109722019A5080172074 @default.
• W2109722019 hasBestOaLocation W21097220191 @default.
• W2109722019 hasConcept C105641010 @default.
• W2109722019 hasConcept C118552586 @default.
• W2109722019 hasConcept C141071460 @default.
• W2109722019 hasConcept C15744967 @default.
• W2109722019 hasConcept C159110408 @default.
• W2109722019 hasConcept C169900460 @default.
• W2109722019 hasConcept C2778186239 @default.
• W2109722019 hasConcept C2779513729 @default.
• W2109722019 hasConcept C2779951463 @default.
• W2109722019 hasConcept C2780803581 @default.
• W2109722019 hasConcept C2781099131 @default.
• W2109722019 hasConcept C71924100 @default.
• W2109722019 hasConceptScore W2109722019C105641010 @default.
• W2109722019 hasConceptScore W2109722019C118552586 @default.
• W2109722019 hasConceptScore W2109722019C141071460 @default.
• W2109722019 hasConceptScore W2109722019C15744967 @default.
• W2109722019 hasConceptScore W2109722019C159110408 @default.
• W2109722019 hasConceptScore W2109722019C169900460 @default.
• W2109722019 hasConceptScore W2109722019C2778186239 @default.
• W2109722019 hasConceptScore W2109722019C2779513729 @default.
• W2109722019 hasConceptScore W2109722019C2779951463 @default.
• W2109722019 hasConceptScore W2109722019C2780803581 @default.
• W2109722019 hasConceptScore W2109722019C2781099131 @default.
• W2109722019 hasConceptScore W2109722019C71924100 @default.
• W2109722019 hasFunder F4320308385 @default.
• W2109722019 hasIssue "11" @default.
• W2109722019 hasLocation W21097220191 @default.

• next