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- W2109835681 abstract "Although liver transplantation (LT) is the only effective treatment option forhepatopulmonary syndrome (HPS), the post-LT morbidity and mortality havebeen high for patients with severe HPS. We performed post-LT embolotherapy ina 10-year-old boy who had severe type I HPS preoperatively, but he failed torecover early from his hypoxemic symptoms after an LT. Multiple embolizationswere then successfully performed on the major branches that formed the abnor-mal vascular structures. After the embolotherapy, the patient had symptomaticimprovement and he was discharged without complications.epatopulmonary syndrome (HPS) is a pulmonary vascular disorder that ischaracterized by the clinical triad of chronic liver disease, arteriovenousshunts due to intrapulmonary vasodilatation, and arterial hypoxemia (1,2). The pathophysiological mechanisms associated with HPS have not been identified.Although HPS is most commonly found in patients with cirrhosis, it has also been seenin patients with portal hypertension in the absence of cirrhosis, and HPS has also beenreported in the setting of acute and chronic hepatitis in the absence of portal hyperten-sion (1, 3). The diagnosis of HPS is made by identifying the intrapulmonary shunts inthose patients with liver disease and hypoxemia. The shunts can be qualitativelyidentified by performing contrast echocardiography and they can also be quantita-tively measured by performing 99m-Tc macroaggregated albumin (MAA) lungperfusion scanning (1-5).There is currently no effective medical treatment for HPS. Liver transplantation (LT)is considered as the only mainstay of therapy for HPS (1, 2). However, HPS may notbe reversible even after an LT in severe cases. A low preoperative partial pressure ofarterial oxygen (PaO" @default.
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- W2109835681 date "2010-01-01" @default.
- W2109835681 modified "2023-09-26" @default.
- W2109835681 title "Pulmonary Artery Embolotherapy in a Patient with Type I Hepatopulmonary Syndrome after Liver Transplantation" @default.
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- W2109835681 doi "https://doi.org/10.3348/kjr.2010.11.4.485" @default.
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