Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109843940> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2109843940 abstract "Coding theory has several applications in Genetics and Bioengineering. Thisthesis concentrates on a specific application from Computational Biology. Thisconcerns the construction of new DNA codes which satisfy certain combinatorialconstraints, using an alphabet of four symbols. The interest in these codesarises because it is possible to synthesise short single strands of DNA known asoligonucleotides. The codes can be useful in the design of these oligonucleotides.For example, the codes are used in DNA computing, as bar codes in molecularlibraries and in microarray technologies.The computer algebra system Magma, which deals successfully with codingtheory computation, is applied initially to the construction of DNA codes sat-isfying a GC-content constraint and a minimum Hamming distance constraint.The constraints are specified to avoid unwanted hybridizations and to ensureuniform melting temperatures. Additionally, another constraint, known as areverse-complement constraint, is added to further prevent unwanted hybridiza-tions. This additional constraint is studied using involutions in a permutationgroup. Codes constructed in this thesis are derived from linear codes over GF(4)and Z4 and additive codes over GF(4). Previous approaches to the constructionof these codes are extended in several ways. Longer codes are constructed, theexamination of cyclic and extended cyclic codes is more comprehensive, andcosets of codes are considered. In addition, attention is paid to the mappingfrom field or ring elements to the DNA nucleotides; different mappings can givedifferent lower bounds. Further improvements have been made after the tech-niques of shortening and puncturing are applied to the table of best codes, andalso by searching for codes in the tables that have an all-ones vector in their dual.The use of a database of best known linear codes is also considered. In manycases codes are obtained which are larger than the best codes currently known.In the case of codes of length greater than twenty, linear DNA codes have notbeen constructed previously and so all codes obtained are the best known re-sults. Generator polynomials are given for the codes constructed. Coset leadersare also given in cases where cosets of linear codes are used. Thus it is possiblefor the reader to construct the codes without repeating the work presented inthe thesis. Additionally, files of codewords are available online when the codesconstructed are the best known codes and have fewer than 50000 codewords." @default.
- W2109843940 created "2016-06-24" @default.
- W2109843940 creator A5080859831 @default.
- W2109843940 date "2011-01-01" @default.
- W2109843940 modified "2023-09-23" @default.
- W2109843940 title "The construction of DNA codes using a computer algebra system" @default.
- W2109843940 cites W1484564260 @default.
- W2109843940 cites W1562183207 @default.
- W2109843940 cites W1562861155 @default.
- W2109843940 cites W1584613487 @default.
- W2109843940 cites W1606480398 @default.
- W2109843940 cites W1937914841 @default.
- W2109843940 cites W1977312644 @default.
- W2109843940 cites W1981073765 @default.
- W2109843940 cites W2009266565 @default.
- W2109843940 cites W2017423606 @default.
- W2109843940 cites W2027603534 @default.
- W2109843940 cites W2055688407 @default.
- W2109843940 cites W2073036100 @default.
- W2109843940 cites W2074993099 @default.
- W2109843940 cites W2090906256 @default.
- W2109843940 cites W2099215797 @default.
- W2109843940 cites W2106981830 @default.
- W2109843940 cites W2122599407 @default.
- W2109843940 cites W2129910432 @default.
- W2109843940 cites W2140061263 @default.
- W2109843940 cites W2149532209 @default.
- W2109843940 cites W2159511216 @default.
- W2109843940 cites W2162150545 @default.
- W2109843940 cites W2167413626 @default.
- W2109843940 cites W2171843169 @default.
- W2109843940 cites W2303014183 @default.
- W2109843940 cites W3139815204 @default.
- W2109843940 cites W43688602 @default.
- W2109843940 cites W2020232396 @default.
- W2109843940 hasPublicationYear "2011" @default.
- W2109843940 type Work @default.
- W2109843940 sameAs 2109843940 @default.
- W2109843940 citedByCount "3" @default.
- W2109843940 countsByYear W21098439402015 @default.
- W2109843940 countsByYear W21098439402016 @default.
- W2109843940 countsByYear W21098439402018 @default.
- W2109843940 crossrefType "dissertation" @default.
- W2109843940 hasAuthorship W2109843940A5080859831 @default.
- W2109843940 hasConcept C11413529 @default.
- W2109843940 hasConcept C157125643 @default.
- W2109843940 hasConcept C2400350 @default.
- W2109843940 hasConcept C2524010 @default.
- W2109843940 hasConcept C2776036281 @default.
- W2109843940 hasConcept C33923547 @default.
- W2109843940 hasConcept C41008148 @default.
- W2109843940 hasConcept C57273362 @default.
- W2109843940 hasConcept C80444323 @default.
- W2109843940 hasConceptScore W2109843940C11413529 @default.
- W2109843940 hasConceptScore W2109843940C157125643 @default.
- W2109843940 hasConceptScore W2109843940C2400350 @default.
- W2109843940 hasConceptScore W2109843940C2524010 @default.
- W2109843940 hasConceptScore W2109843940C2776036281 @default.
- W2109843940 hasConceptScore W2109843940C33923547 @default.
- W2109843940 hasConceptScore W2109843940C41008148 @default.
- W2109843940 hasConceptScore W2109843940C57273362 @default.
- W2109843940 hasConceptScore W2109843940C80444323 @default.
- W2109843940 hasLocation W21098439401 @default.
- W2109843940 hasOpenAccess W2109843940 @default.
- W2109843940 hasPrimaryLocation W21098439401 @default.
- W2109843940 hasRelatedWork W1632494370 @default.
- W2109843940 hasRelatedWork W2049332272 @default.
- W2109843940 hasRelatedWork W2098183759 @default.
- W2109843940 hasRelatedWork W2118320595 @default.
- W2109843940 hasRelatedWork W2156145975 @default.
- W2109843940 hasRelatedWork W2169662449 @default.
- W2109843940 hasRelatedWork W2220370847 @default.
- W2109843940 hasRelatedWork W2591237754 @default.
- W2109843940 hasRelatedWork W2591325174 @default.
- W2109843940 hasRelatedWork W2616450673 @default.
- W2109843940 hasRelatedWork W2743828512 @default.
- W2109843940 hasRelatedWork W2895191681 @default.
- W2109843940 hasRelatedWork W2919050667 @default.
- W2109843940 hasRelatedWork W2949986063 @default.
- W2109843940 hasRelatedWork W2951406512 @default.
- W2109843940 hasRelatedWork W3104417989 @default.
- W2109843940 hasRelatedWork W3174883025 @default.
- W2109843940 hasRelatedWork W3206565055 @default.
- W2109843940 hasRelatedWork W348408967 @default.
- W2109843940 hasRelatedWork W46587733 @default.
- W2109843940 isParatext "false" @default.
- W2109843940 isRetracted "false" @default.
- W2109843940 magId "2109843940" @default.
- W2109843940 workType "dissertation" @default.