Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109853493> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2109853493 endingPage "420" @default.
- W2109853493 startingPage "414" @default.
- W2109853493 abstract "The effect of prothymosin α on transcriptional elongation has been examined. The addition of prothymosin α to COS-1 and NIH3T3 cell nuclei engaged in run-on transcription stimulated RNA synthesis approximately two- to threefold in a dose-dependent manner. Polyglutamic acid or a random polypeptide composed of glutamic acid, alanine, and tyrosine, did not substitute for prothymosin α. Enhanced transcription occurred in the presence of high and low doses of actinomycin D and in the presence of α-amanitin, but not in nuclear extracts. The stimulatory effect was dependent on a limiting concentration of one nucleoside triphosphate and was nearly abrogated by saturating levels of precursors. In the presence of Sarkosyl, which itself increases transcription, prothymosin α was almost ineffectual. The data are consistent with a model in which prothymosin α does not interact directly with polymerases but, instead, nonspecifically decreases the barriers to diffusion of charged molecules in electrostatically charged environments." @default.
- W2109853493 created "2016-06-24" @default.
- W2109853493 creator A5060011933 @default.
- W2109853493 creator A5081427839 @default.
- W2109853493 date "2000-12-01" @default.
- W2109853493 modified "2023-10-18" @default.
- W2109853493 title "Prothymosin α Is a Nonspecific Facilitator of Nuclear Processes: Studies of Run-on Transcription" @default.
- W2109853493 cites W1516627538 @default.
- W2109853493 cites W1545396114 @default.
- W2109853493 cites W1595608936 @default.
- W2109853493 cites W1854935287 @default.
- W2109853493 cites W1963965358 @default.
- W2109853493 cites W1975588265 @default.
- W2109853493 cites W1977344910 @default.
- W2109853493 cites W1983365110 @default.
- W2109853493 cites W1988298211 @default.
- W2109853493 cites W1998508637 @default.
- W2109853493 cites W2001137823 @default.
- W2109853493 cites W2002550426 @default.
- W2109853493 cites W2017108484 @default.
- W2109853493 cites W2023491365 @default.
- W2109853493 cites W2024658791 @default.
- W2109853493 cites W202855464 @default.
- W2109853493 cites W2029777164 @default.
- W2109853493 cites W2031793115 @default.
- W2109853493 cites W2033519549 @default.
- W2109853493 cites W2051301115 @default.
- W2109853493 cites W2054802776 @default.
- W2109853493 cites W2057853766 @default.
- W2109853493 cites W2066455034 @default.
- W2109853493 cites W2071894185 @default.
- W2109853493 cites W2080522158 @default.
- W2109853493 cites W2080766591 @default.
- W2109853493 cites W2083426364 @default.
- W2109853493 cites W2089475204 @default.
- W2109853493 cites W2110374428 @default.
- W2109853493 cites W2123851239 @default.
- W2109853493 cites W2124166821 @default.
- W2109853493 cites W2164568163 @default.
- W2109853493 cites W2170187435 @default.
- W2109853493 cites W2259111283 @default.
- W2109853493 cites W2395749482 @default.
- W2109853493 cites W2461377988 @default.
- W2109853493 doi "https://doi.org/10.1006/prep.2000.1332" @default.
- W2109853493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11087681" @default.
- W2109853493 hasPublicationYear "2000" @default.
- W2109853493 type Work @default.
- W2109853493 sameAs 2109853493 @default.
- W2109853493 citedByCount "11" @default.
- W2109853493 countsByYear W21098534932012 @default.
- W2109853493 crossrefType "journal-article" @default.
- W2109853493 hasAuthorship W2109853493A5060011933 @default.
- W2109853493 hasAuthorship W2109853493A5081427839 @default.
- W2109853493 hasConcept C12554922 @default.
- W2109853493 hasConcept C138885662 @default.
- W2109853493 hasConcept C179926584 @default.
- W2109853493 hasConcept C185592680 @default.
- W2109853493 hasConcept C2779856020 @default.
- W2109853493 hasConcept C41895202 @default.
- W2109853493 hasConcept C515207424 @default.
- W2109853493 hasConcept C55493867 @default.
- W2109853493 hasConcept C86803240 @default.
- W2109853493 hasConcept C95444343 @default.
- W2109853493 hasConceptScore W2109853493C12554922 @default.
- W2109853493 hasConceptScore W2109853493C138885662 @default.
- W2109853493 hasConceptScore W2109853493C179926584 @default.
- W2109853493 hasConceptScore W2109853493C185592680 @default.
- W2109853493 hasConceptScore W2109853493C2779856020 @default.
- W2109853493 hasConceptScore W2109853493C41895202 @default.
- W2109853493 hasConceptScore W2109853493C515207424 @default.
- W2109853493 hasConceptScore W2109853493C55493867 @default.
- W2109853493 hasConceptScore W2109853493C86803240 @default.
- W2109853493 hasConceptScore W2109853493C95444343 @default.
- W2109853493 hasIssue "3" @default.
- W2109853493 hasLocation W21098534931 @default.
- W2109853493 hasLocation W21098534932 @default.
- W2109853493 hasOpenAccess W2109853493 @default.
- W2109853493 hasPrimaryLocation W21098534931 @default.
- W2109853493 hasRelatedWork W1500760553 @default.
- W2109853493 hasRelatedWork W1537421998 @default.
- W2109853493 hasRelatedWork W1601392889 @default.
- W2109853493 hasRelatedWork W1982845316 @default.
- W2109853493 hasRelatedWork W2008301391 @default.
- W2109853493 hasRelatedWork W2021126964 @default.
- W2109853493 hasRelatedWork W2044257351 @default.
- W2109853493 hasRelatedWork W2166972095 @default.
- W2109853493 hasRelatedWork W2186218390 @default.
- W2109853493 hasRelatedWork W3095558382 @default.
- W2109853493 hasVolume "20" @default.
- W2109853493 isParatext "false" @default.
- W2109853493 isRetracted "false" @default.
- W2109853493 magId "2109853493" @default.
- W2109853493 workType "article" @default.