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• W2109871368 abstract "B cells are one of the targets of Friend virus (FV) infection, a well-established mouse model often used to study retroviral infections in vivo. Although B cells may be effective in stimulating cytotoxic T lymphocyte responses, studies involving their role in FV infection have mainly focused on neutralizing antibody production. Here we show that polyclonal activation of B cells promotes their infection with FV both in vitro and in vivo. Furthermore, we demonstrate that complement opsonization of Friend murine leukemia virus (F-MuLV) enhances infection of B cells, which correlates with increased potency of B cells to activate FV-specific CD8(+) T cells." @default.
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• W2109871368 date "2011-01-15" @default.
• W2109871368 modified "2023-10-18" @default.
• W2109871368 title "Complement Opsonization Enhances Friend Virus Infection of B Cells and Thereby Amplifies the Virus-Specific CD8 ⁺ T Cell Response" @default.
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• W2109871368 doi "https://doi.org/10.1128/jvi.01821-10" @default.
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