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- W2109872238 abstract "ObjectiveTo estimate the relation between serum free fatty acids (FFAs) and severe preeclampsia in Egypt.MethodsTwenty cases with severe preeclampsia (blood pressure ⩾ 160/110 after 20th week of gestation and proteinuria ⩾ 2.5 gm/24 h urine) were matched with 20 normotensive pregnant controls for age, and BMI. All study participants were registered to Elshatby Maternity University Hospital within a period of 10 months. Evaluation of serum fasting FFAs, uric acid, liver transaminases (AST, ALT) during delivery were done.ResultsThe mean level of FFAs was significantly elevated in preeclampsia cases compared to women with normal blood pressure (2.12 ± 2.64, 0.43 ± 0.29 respectively, p = 0.003). Also, cases with high FFAs levels had significant increased levels of serum uric acid than control women with normal blood pressure (6.38 ± 1.25, 5.05 ± 1.85 respectively, p = 0.006). Women with high levels of serum FFAs had more than two folds increased risk for neonatal admission to Neonatal Intensive Care Unit OR (2.4).ConclusionThis study suggests that elevated total serum FFAs might be an associated predisposing factor with preeclampsia in non-obese pregnant women." @default.
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- W2109872238 date "2011-12-01" @default.
- W2109872238 modified "2023-10-15" @default.
- W2109872238 title "Can serum free fatty acids assessment predict severe preeclampsia?" @default.
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- W2109872238 doi "https://doi.org/10.1016/j.ajme.2011.09.003" @default.
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