Matches in SemOpenAlex for { <https://semopenalex.org/work/W2109886945> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2109886945 endingPage "46" @default.
- W2109886945 startingPage "339" @default.
- W2109886945 abstract "Porous titanium-nickel (PTN) represents a new biomaterial with orthopedic applications as a long-term implant. Because of its nickel content, PTN was tested for its potential to stimulate sensitization, irritation, and systemic toxicity reactions after semi-physiological extraction. In order to do so, an in vivo biocompatibility evaluation was performed following three ISO-standardized methods using accepted animal models for immunity testing: the classical skin sensitization assay (Buehler patch test) in guinea pigs, the rabbit intracutaneous test, and the systemic injection test in mice. The Buehler patch test in guinea pigs revealed no significant change in skin reactions such as erythema or swelling between the induction and the challenge period. In the rabbit intracutaneous irritation test, no irritation or sensitization reactions were observed in saline-extracted PTN samples. Negligible to slight irritation was observed at some of the sites involving PTN samples extracted in cottonseed oil, however the resulting primary irritation index was similar to the one elicited by the blank solution itself. Finally, no toxic symptoms were observed with any of the mice injected with porous titanium-nickel extracts during the acute systemic toxicity test. Based on the above results, porous titanium-nickel is considered to be a non-sensitizing, non-irritant, and non-toxic biomaterial for medical applications." @default.
- W2109886945 created "2016-06-24" @default.
- W2109886945 creator A5007968357 @default.
- W2109886945 creator A5031049243 @default.
- W2109886945 creator A5037223383 @default.
- W2109886945 creator A5040422468 @default.
- W2109886945 date "2002-01-01" @default.
- W2109886945 modified "2023-10-18" @default.
- W2109886945 title "A new porous titanium-nickel alloy: part 2. Sensitization, irritation and acute systemic toxicity evaluation." @default.
- W2109886945 cites W1750985701 @default.
- W2109886945 cites W18186738 @default.
- W2109886945 cites W1978713435 @default.
- W2109886945 cites W1981834848 @default.
- W2109886945 cites W1987679341 @default.
- W2109886945 cites W1992176297 @default.
- W2109886945 cites W1994435684 @default.
- W2109886945 cites W2011156568 @default.
- W2109886945 cites W2012346785 @default.
- W2109886945 cites W2020076099 @default.
- W2109886945 cites W2021005128 @default.
- W2109886945 cites W2025467911 @default.
- W2109886945 cites W2025561084 @default.
- W2109886945 cites W2028039664 @default.
- W2109886945 cites W2053995998 @default.
- W2109886945 cites W2069577787 @default.
- W2109886945 cites W2076398557 @default.
- W2109886945 cites W2089338521 @default.
- W2109886945 cites W2101193493 @default.
- W2109886945 cites W2106682437 @default.
- W2109886945 cites W2122306190 @default.
- W2109886945 cites W2139152429 @default.
- W2109886945 cites W2143310519 @default.
- W2109886945 cites W2166882028 @default.
- W2109886945 cites W2170266248 @default.
- W2109886945 cites W2182927225 @default.
- W2109886945 cites W2223789076 @default.
- W2109886945 cites W2417206496 @default.
- W2109886945 cites W27352254 @default.
- W2109886945 cites W31714167 @default.
- W2109886945 cites W2461867195 @default.
- W2109886945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12652028" @default.
- W2109886945 hasPublicationYear "2002" @default.
- W2109886945 type Work @default.
- W2109886945 sameAs 2109886945 @default.
- W2109886945 citedByCount "7" @default.
- W2109886945 countsByYear W21098869452017 @default.
- W2109886945 countsByYear W21098869452018 @default.
- W2109886945 crossrefType "journal-article" @default.
- W2109886945 hasAuthorship W2109886945A5007968357 @default.
- W2109886945 hasAuthorship W2109886945A5031049243 @default.
- W2109886945 hasAuthorship W2109886945A5037223383 @default.
- W2109886945 hasAuthorship W2109886945A5040422468 @default.
- W2109886945 hasConcept C136229726 @default.
- W2109886945 hasConcept C141071460 @default.
- W2109886945 hasConcept C178790620 @default.
- W2109886945 hasConcept C185592680 @default.
- W2109886945 hasConcept C203014093 @default.
- W2109886945 hasConcept C2776217527 @default.
- W2109886945 hasConcept C2777063393 @default.
- W2109886945 hasConcept C2777230088 @default.
- W2109886945 hasConcept C2778414984 @default.
- W2109886945 hasConcept C2779121184 @default.
- W2109886945 hasConcept C29730261 @default.
- W2109886945 hasConcept C71924100 @default.
- W2109886945 hasConcept C98274493 @default.
- W2109886945 hasConceptScore W2109886945C136229726 @default.
- W2109886945 hasConceptScore W2109886945C141071460 @default.
- W2109886945 hasConceptScore W2109886945C178790620 @default.
- W2109886945 hasConceptScore W2109886945C185592680 @default.
- W2109886945 hasConceptScore W2109886945C203014093 @default.
- W2109886945 hasConceptScore W2109886945C2776217527 @default.
- W2109886945 hasConceptScore W2109886945C2777063393 @default.
- W2109886945 hasConceptScore W2109886945C2777230088 @default.
- W2109886945 hasConceptScore W2109886945C2778414984 @default.
- W2109886945 hasConceptScore W2109886945C2779121184 @default.
- W2109886945 hasConceptScore W2109886945C29730261 @default.
- W2109886945 hasConceptScore W2109886945C71924100 @default.
- W2109886945 hasConceptScore W2109886945C98274493 @default.
- W2109886945 hasIssue "4" @default.
- W2109886945 hasLocation W21098869451 @default.
- W2109886945 hasOpenAccess W2109886945 @default.
- W2109886945 hasPrimaryLocation W21098869451 @default.
- W2109886945 hasRelatedWork W2010139995 @default.
- W2109886945 hasRelatedWork W2054209513 @default.
- W2109886945 hasRelatedWork W2055763109 @default.
- W2109886945 hasRelatedWork W2066905849 @default.
- W2109886945 hasRelatedWork W2109886945 @default.
- W2109886945 hasRelatedWork W2133457301 @default.
- W2109886945 hasRelatedWork W2155292681 @default.
- W2109886945 hasRelatedWork W2352495792 @default.
- W2109886945 hasRelatedWork W2909771661 @default.
- W2109886945 hasRelatedWork W302042297 @default.
- W2109886945 hasVolume "12" @default.
- W2109886945 isParatext "false" @default.
- W2109886945 isRetracted "false" @default.
- W2109886945 magId "2109886945" @default.
- W2109886945 workType "article" @default.