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- W2109894597 abstract "Ribonucleoside diphosphate reductase (RNR) is located in discrete foci in a number that increases with the overlapping of replication cycles in Escherichia coli . Comparison of the numbers of RNR, DnaX and SeqA protein foci with the number of replication forks at different growth rates reveals that fork : focus ratios augment with increasing growth rates, suggesting a higher cohesion of the three protein foci with increasing number of forks per cell. Quantification of NrdB and SeqA proteins per cell showed: (i) a higher amount of RNR per focus at faster growth rates, which sustains the higher cohesion of RNR foci with higher numbers of forks per cell; and (ii) an equivalent amount of RNR per replication fork, independent of the number of the latter." @default.
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- W2109894597 date "2011-08-01" @default.
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- W2109894597 title "Organization of ribonucleoside diphosphate reductase during multifork chromosome replication in Escherichia coli" @default.
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- W2109894597 doi "https://doi.org/10.1099/mic.0.049478-0" @default.
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