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- W2109903386 abstract "Patients with rheumatoid arthritis (RA) have an almost twofold increase of cardiovascular (CV) mortality and morbidity as compared with the general population and it is thought that chronic inflammation contributes to this association.1 Serum uric acid (SUA) can contribute to low-grade inflammation via increased production of C reactive protein (CRP) and influences cytokine and superoxide production by circulating neutrophils.2 ,3 In RA, higher levels of SUA have been associated with a higher prevalence of CV disease.4 At the joint level, monosodium urate crystals can negatively influence local bone remodelling by excessive osteoclast formation and reduced osteoblast differentiation.5, …" @default.
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- W2109903386 date "2012-03-22" @default.
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- W2109903386 title "No impact of serum uric acid on the outcome of recent-onset arthritis" @default.
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- W2109903386 doi "https://doi.org/10.1136/annrheumdis-2011-201027" @default.
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