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- W2110052543 abstract "The effect of ultrasound on the permeability of blood vessels to nano-emulsion droplets was investigated using excised mouse carotid arteries as model blood vessels. Perfluorocarbon nano-droplets were formed by perfluoro-15-crown-5-ether and stabilized by poly(ethylene oxide)-co-poly(DL-lactide) block co-polymer shells. Nano-droplet fluorescence was imparted by interaction with fluorescein isothiocyanate-dextran (molecular weight = 70,000 Da). The permeability of carotid arteries to nano-droplets was studied in the presence and absence of continuous wave or pulsed therapeutic 1-MHz ultrasound. The data indicated that the application of ultrasound resulted in permeabilization of the vascular wall to nano-droplets. The effect of continuous wave ultrasound was substantially stronger than that of pulsed ultrasound of the same total energy. No effect of blood vessel pre-treatment with ultrasound was observed." @default.
- W2110052543 created "2016-06-24" @default.
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- W2110052543 date "2013-10-01" @default.
- W2110052543 modified "2023-09-26" @default.
- W2110052543 title "Effect of Ultrasound on the Permeability of Vascular Wall to Nano-emulsion Droplets" @default.
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- W2110052543 doi "https://doi.org/10.1016/j.ultrasmedbio.2013.04.008" @default.
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