FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110052624> ?p ?o ?g. }

• W2110052624 endingPage "H1382" @default.
• W2110052624 startingPage "H1376" @default.
• W2110052624 abstract "The Na/Ca exchanger encoded by the NCX1 gene plays an important role in calcium homeostasis in cardiac muscle. We previously identified three in vitro signaling pathways that are of major importance in the regulation of Na/Ca exchanger gene expression in neonatal cardiac myocytes, the protein kinase A (PKA) and protein kinase C (PKC) pathways, and intracellular Ca(2+). To determine whether these pathways are important in vivo, we stimulated the PKA and PKC pathways and examined functional expression of the Na/Ca exchanger in adult rat heart. After a 3- and 7-day treatment, norepinephrine (200 microg x kg(-1) x h(-1)), isoproterenol (150 microg x kg(-1) x h(-1)), and phenylephrine (200 microg x kg(-1) x h(-1)) each stimulated a significant increase in NCX1 mRNA levels (35-85%, P < 0.05). Norepinephrine also stimulated a 35% increase in protein abundance (P < 0.05), a 20% decrease in relaxation duration (P < 0.05), and a 25% reduction in the fluorescence decay constant (P < 0.05) after a 7-day treatment. We conclude that a 7-day treatment of alpha- and beta-adrenergic agonists increases the expression of functional Na/Ca exchangers in adult rat heart." @default.
• W2110052624 created "2016-06-24" @default.
• W2110052624 creator A5007706452 @default.
• W2110052624 creator A5012860789 @default.
• W2110052624 creator A5018549340 @default.
• W2110052624 creator A5040266659 @default.
• W2110052624 creator A5066666096 @default.
• W2110052624 creator A5082857119 @default.
• W2110052624 date "2001-03-01" @default.
• W2110052624 modified "2023-10-14" @default.
• W2110052624 title "In vivo regulation of Na/Ca exchanger expression by adrenergic effectors" @default.
• W2110052624 cites W1559767698 @default.
• W2110052624 cites W1916800720 @default.
• W2110052624 cites W1967428301 @default.
• W2110052624 cites W1970411413 @default.
• W2110052624 cites W1973652501 @default.
• W2110052624 cites W1977810408 @default.
• W2110052624 cites W2005559165 @default.
• W2110052624 cites W2007751518 @default.
• W2110052624 cites W2015122100 @default.
• W2110052624 cites W2036555063 @default.
• W2110052624 cites W2042646075 @default.
• W2110052624 cites W2048026045 @default.
• W2110052624 cites W2059201211 @default.
• W2110052624 cites W2072482237 @default.
• W2110052624 cites W2099654084 @default.
• W2110052624 cites W2100509042 @default.
• W2110052624 cites W2104287466 @default.
• W2110052624 cites W2120337309 @default.
• W2110052624 cites W2147959747 @default.
• W2110052624 cites W2157228100 @default.
• W2110052624 cites W2160171079 @default.
• W2110052624 cites W2164931274 @default.
• W2110052624 cites W2255341027 @default.
• W2110052624 cites W2415909923 @default.
• W2110052624 cites W3149576662 @default.
• W2110052624 cites W4362071483 @default.
• W2110052624 doi "https://doi.org/10.1152/ajpheart.2001.280.3.h1376" @default.
• W2110052624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11179087" @default.
• W2110052624 hasPublicationYear "2001" @default.
• W2110052624 type Work @default.
• W2110052624 sameAs 2110052624 @default.
• W2110052624 citedByCount "33" @default.
• W2110052624 countsByYear W21100526242012 @default.
• W2110052624 countsByYear W21100526242013 @default.
• W2110052624 countsByYear W21100526242016 @default.
• W2110052624 crossrefType "journal-article" @default.
• W2110052624 hasAuthorship W2110052624A5007706452 @default.
• W2110052624 hasAuthorship W2110052624A5012860789 @default.
• W2110052624 hasAuthorship W2110052624A5018549340 @default.
• W2110052624 hasAuthorship W2110052624A5040266659 @default.
• W2110052624 hasAuthorship W2110052624A5066666096 @default.
• W2110052624 hasAuthorship W2110052624A5082857119 @default.
• W2110052624 hasConcept C104317684 @default.
• W2110052624 hasConcept C126322002 @default.
• W2110052624 hasConcept C134018914 @default.
• W2110052624 hasConcept C150194340 @default.
• W2110052624 hasConcept C150903083 @default.
• W2110052624 hasConcept C181080969 @default.
• W2110052624 hasConcept C184235292 @default.
• W2110052624 hasConcept C185592680 @default.
• W2110052624 hasConcept C195794163 @default.
• W2110052624 hasConcept C207001950 @default.
• W2110052624 hasConcept C207200792 @default.
• W2110052624 hasConcept C2777735026 @default.
• W2110052624 hasConcept C2777952589 @default.
• W2110052624 hasConcept C519063684 @default.
• W2110052624 hasConcept C55493867 @default.
• W2110052624 hasConcept C62478195 @default.
• W2110052624 hasConcept C63645605 @default.
• W2110052624 hasConcept C71924100 @default.
• W2110052624 hasConcept C84393581 @default.
• W2110052624 hasConcept C86803240 @default.
• W2110052624 hasConcept C95444343 @default.
• W2110052624 hasConcept C97029542 @default.
• W2110052624 hasConceptScore W2110052624C104317684 @default.
• W2110052624 hasConceptScore W2110052624C126322002 @default.
• W2110052624 hasConceptScore W2110052624C134018914 @default.
• W2110052624 hasConceptScore W2110052624C150194340 @default.
• W2110052624 hasConceptScore W2110052624C150903083 @default.
• W2110052624 hasConceptScore W2110052624C181080969 @default.
• W2110052624 hasConceptScore W2110052624C184235292 @default.
• W2110052624 hasConceptScore W2110052624C185592680 @default.
• W2110052624 hasConceptScore W2110052624C195794163 @default.
• W2110052624 hasConceptScore W2110052624C207001950 @default.
• W2110052624 hasConceptScore W2110052624C207200792 @default.
• W2110052624 hasConceptScore W2110052624C2777735026 @default.
• W2110052624 hasConceptScore W2110052624C2777952589 @default.
• W2110052624 hasConceptScore W2110052624C519063684 @default.
• W2110052624 hasConceptScore W2110052624C55493867 @default.
• W2110052624 hasConceptScore W2110052624C62478195 @default.
• W2110052624 hasConceptScore W2110052624C63645605 @default.
• W2110052624 hasConceptScore W2110052624C71924100 @default.
• W2110052624 hasConceptScore W2110052624C84393581 @default.
• W2110052624 hasConceptScore W2110052624C86803240 @default.
• W2110052624 hasConceptScore W2110052624C95444343 @default.
• W2110052624 hasConceptScore W2110052624C97029542 @default.
• W2110052624 hasIssue "3" @default.

• next