Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110109818> ?p ?o ?g. }
- W2110109818 endingPage "337" @default.
- W2110109818 startingPage "330" @default.
- W2110109818 abstract "Chemokines and their receptors have critical roles in inflammatory and immunological responses, and thus their genetic contribution to various human disorders needs investigation. In this study, systematic variation screening of the entire coding regions of CXCR1 (IL8RA), CXCR2 (IL8RB) and CXCR3 was carried out, using genomic DNA from a large number of Japanese healthy individuals and patients with rheumatic diseases. In addition to the previously reported variations in CXCR1 and in CXCR2, two non-synonymous, two synonymous substitutions and one nonsense mutation of CXCR1, one non-synonymous and two synonymous substitutions of CXCR2, two non-synonymous substitutions of CXCR3 were newly identified. The common single nucleotide polymorphisms (SNPs) at CXCR1 codon 827 and CXCR2 codon 786 were in strong linkage disequilibrium. In addition, familial analysis indicated that human CXCR3 is located on chromosome X. No significant association was observed between the variations and the tested rheumatic diseases. However, CXCR variations identified in this study will provide valuable information for the future studies in medical sciences as well as in human genetics." @default.
- W2110109818 created "2016-06-24" @default.
- W2110109818 creator A5019068702 @default.
- W2110109818 creator A5040367383 @default.
- W2110109818 creator A5063080687 @default.
- W2110109818 date "2000-06-01" @default.
- W2110109818 modified "2023-10-16" @default.
- W2110109818 title "Single nucleotide polymorphisms in the coding regions of human CXC-chemokine receptors CXCR1, CXCR2 and CXCR3" @default.
- W2110109818 cites W1483257978 @default.
- W2110109818 cites W1511166699 @default.
- W2110109818 cites W1511211960 @default.
- W2110109818 cites W1579519593 @default.
- W2110109818 cites W1580379409 @default.
- W2110109818 cites W1602835962 @default.
- W2110109818 cites W1636221219 @default.
- W2110109818 cites W1669115568 @default.
- W2110109818 cites W1898182243 @default.
- W2110109818 cites W1974083313 @default.
- W2110109818 cites W1974575697 @default.
- W2110109818 cites W1984493755 @default.
- W2110109818 cites W1998605540 @default.
- W2110109818 cites W2007684414 @default.
- W2110109818 cites W2010148594 @default.
- W2110109818 cites W2025930905 @default.
- W2110109818 cites W2026444780 @default.
- W2110109818 cites W2027712750 @default.
- W2110109818 cites W2028486645 @default.
- W2110109818 cites W2033114461 @default.
- W2110109818 cites W2037832428 @default.
- W2110109818 cites W2039137468 @default.
- W2110109818 cites W2040183153 @default.
- W2110109818 cites W2045281561 @default.
- W2110109818 cites W2058902088 @default.
- W2110109818 cites W2059812096 @default.
- W2110109818 cites W2066618985 @default.
- W2110109818 cites W2078888764 @default.
- W2110109818 cites W2081596482 @default.
- W2110109818 cites W2082959093 @default.
- W2110109818 cites W2091040274 @default.
- W2110109818 cites W2115344634 @default.
- W2110109818 cites W2117342688 @default.
- W2110109818 cites W2120773157 @default.
- W2110109818 cites W2133729421 @default.
- W2110109818 cites W2137299974 @default.
- W2110109818 cites W2146203649 @default.
- W2110109818 cites W2150782063 @default.
- W2110109818 cites W2152348310 @default.
- W2110109818 cites W2157959080 @default.
- W2110109818 cites W2159487337 @default.
- W2110109818 cites W2160129587 @default.
- W2110109818 cites W2168651519 @default.
- W2110109818 cites W2175999997 @default.
- W2110109818 cites W2333200822 @default.
- W2110109818 cites W2383231537 @default.
- W2110109818 cites W2397893181 @default.
- W2110109818 cites W2399349952 @default.
- W2110109818 cites W625849822 @default.
- W2110109818 doi "https://doi.org/10.1038/sj.gene.6363682" @default.
- W2110109818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11196695" @default.
- W2110109818 hasPublicationYear "2000" @default.
- W2110109818 type Work @default.
- W2110109818 sameAs 2110109818 @default.
- W2110109818 citedByCount "32" @default.
- W2110109818 countsByYear W21101098182013 @default.
- W2110109818 countsByYear W21101098182014 @default.
- W2110109818 countsByYear W21101098182018 @default.
- W2110109818 countsByYear W21101098182019 @default.
- W2110109818 countsByYear W21101098182022 @default.
- W2110109818 crossrefType "journal-article" @default.
- W2110109818 hasAuthorship W2110109818A5019068702 @default.
- W2110109818 hasAuthorship W2110109818A5040367383 @default.
- W2110109818 hasAuthorship W2110109818A5063080687 @default.
- W2110109818 hasBestOaLocation W21101098181 @default.
- W2110109818 hasConcept C104317684 @default.
- W2110109818 hasConcept C12823836 @default.
- W2110109818 hasConcept C13373296 @default.
- W2110109818 hasConcept C135763542 @default.
- W2110109818 hasConcept C141231307 @default.
- W2110109818 hasConcept C149904235 @default.
- W2110109818 hasConcept C153209595 @default.
- W2110109818 hasConcept C170493617 @default.
- W2110109818 hasConcept C35605836 @default.
- W2110109818 hasConcept C54355233 @default.
- W2110109818 hasConcept C84913492 @default.
- W2110109818 hasConcept C86803240 @default.
- W2110109818 hasConcept C91779695 @default.
- W2110109818 hasConceptScore W2110109818C104317684 @default.
- W2110109818 hasConceptScore W2110109818C12823836 @default.
- W2110109818 hasConceptScore W2110109818C13373296 @default.
- W2110109818 hasConceptScore W2110109818C135763542 @default.
- W2110109818 hasConceptScore W2110109818C141231307 @default.
- W2110109818 hasConceptScore W2110109818C149904235 @default.
- W2110109818 hasConceptScore W2110109818C153209595 @default.
- W2110109818 hasConceptScore W2110109818C170493617 @default.
- W2110109818 hasConceptScore W2110109818C35605836 @default.
- W2110109818 hasConceptScore W2110109818C54355233 @default.
- W2110109818 hasConceptScore W2110109818C84913492 @default.
- W2110109818 hasConceptScore W2110109818C86803240 @default.