FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110113876> ?p ?o ?g. }

• W2110113876 endingPage "4539" @default.
• W2110113876 startingPage "4533" @default.
• W2110113876 abstract "P a catecholamine-producing tumor arising in the adrenal medulla, has an estimated incidence of two to eight cases per million persons annually (1, 2). Its clinical hallmark is sustained or intermittent hypertension often associated with paroxysmal symptoms (3). Pheochromocytoma should also be considered if a patient has labile hypertension, hypertension resistant to antihypertensive therapy, or paroxysmal symptoms (“spells”) (3, 4). Correct diagnosis is important because resection of the tumor dramatically reverses the clinical symptoms and may cure the hypertension (5). A missed or delayed diagnosis may cause considerable morbidity and mortality (5, 6). Clinically significant pheochromocytoma was first recognized in 1926 when Cesar Roux in Switzerland and Charles H. Mayo in the United States successfully removed pheochromocytomas to cure the catecholamine-associated symptom complex (7, 8). A biochemical assessment of catecholamine hypersecretion was not possible in 1926. Since then, the diagnostic approach has progressed from clinical impressions and exploratory laparotomies to histamine stimulation and phentolamine suppression tests in the 1940s, crude catecholamine measurements and iv urograms in the 1950s and 1960s, and refined measurements of catecholamine levels and computerized imaging in the 1970s and 1980s. Most laboratories now measure catecholamines by HPLC with electrochemical detection or gas chromatography and mass spectrometry. Catecholamines and their metabolites can be measured in the blood or urine. There are major regional, institutional, and international differences in the approach to the biochemical diagnosis of pheochromocytoma. For example, at Mayo Clinic, physicians have relied on the 24-h urinary excretion of catecholamines and total metanephrines for more than 2 decades (9, 10). If the baseline 24-h urinary studies are normal, the study is repeated when the patient is symptomatic (e.g. with a spell). From 1976–1993, Mayo Clinic clinicians performed histamine and glucagon stimulation tests (with measurement of blood pressure and plasma fractionated catecholamines) in 542 patients in whom pheochromocytoma was highly suspected despite normal 24-h urinary catecholamine or total metanephrine excretion; none of these patients had a positive stimulation test in this setting (11). Thus, we did not find the addition of histamine and glucagon stimulation tests helpful after 24-h urinary testing. The most recent addition to the biochemical testing armamentarium is fractionated plasma free metanephrines, a test proposed to be the superior to urinary testing by some investigators (12, 13). Herein, we focus on the biochemical tests used to diagnose sporadic adrenal pheochromocytoma. To provide perspective, two datasets from Mayo Clinic are summarized: 1) historical data before the use of fractionated free plasma metanephrines (1978–1996), and 2) current data obtained after the introduction of fractionated free plasma metanephrines (after 1998)." @default.
• W2110113876 created "2016-06-24" @default.
• W2110113876 creator A5027785364 @default.
• W2110113876 creator A5057382848 @default.
• W2110113876 creator A5061028131 @default.
• W2110113876 date "2003-10-01" @default.
• W2110113876 modified "2023-10-18" @default.
• W2110113876 title "The Laboratory Diagnosis of Adrenal Pheochromocytoma: The Mayo Clinic Experience" @default.
• W2110113876 cites W157284236 @default.
• W2110113876 cites W1887626071 @default.
• W2110113876 cites W1923537103 @default.
• W2110113876 cites W1964935708 @default.
• W2110113876 cites W1970753312 @default.
• W2110113876 cites W1971427268 @default.
• W2110113876 cites W1976657740 @default.
• W2110113876 cites W1979170245 @default.
• W2110113876 cites W1979422997 @default.
• W2110113876 cites W1982558966 @default.
• W2110113876 cites W1983996547 @default.
• W2110113876 cites W1985097805 @default.
• W2110113876 cites W2021805173 @default.
• W2110113876 cites W2029573559 @default.
• W2110113876 cites W2051742874 @default.
• W2110113876 cites W2065640246 @default.
• W2110113876 cites W2066961609 @default.
• W2110113876 cites W2073136964 @default.
• W2110113876 cites W2095082651 @default.
• W2110113876 cites W2101065691 @default.
• W2110113876 cites W2106018484 @default.
• W2110113876 cites W2137052103 @default.
• W2110113876 cites W2148626383 @default.
• W2110113876 cites W2171815806 @default.
• W2110113876 cites W2461940658 @default.
• W2110113876 cites W4292879218 @default.
• W2110113876 doi "https://doi.org/10.1210/jc.2003-030720" @default.
• W2110113876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14557417" @default.
• W2110113876 hasPublicationYear "2003" @default.
• W2110113876 type Work @default.
• W2110113876 sameAs 2110113876 @default.
• W2110113876 citedByCount "226" @default.
• W2110113876 countsByYear W21101138762012 @default.
• W2110113876 countsByYear W21101138762013 @default.
• W2110113876 countsByYear W21101138762014 @default.
• W2110113876 countsByYear W21101138762015 @default.
• W2110113876 countsByYear W21101138762016 @default.
• W2110113876 countsByYear W21101138762017 @default.
• W2110113876 countsByYear W21101138762018 @default.
• W2110113876 countsByYear W21101138762019 @default.
• W2110113876 countsByYear W21101138762020 @default.
• W2110113876 countsByYear W21101138762021 @default.
• W2110113876 countsByYear W21101138762022 @default.
• W2110113876 countsByYear W21101138762023 @default.
• W2110113876 crossrefType "journal-article" @default.
• W2110113876 hasAuthorship W2110113876A5027785364 @default.
• W2110113876 hasAuthorship W2110113876A5057382848 @default.
• W2110113876 hasAuthorship W2110113876A5061028131 @default.
• W2110113876 hasBestOaLocation W21101138761 @default.
• W2110113876 hasConcept C126322002 @default.
• W2110113876 hasConcept C134018914 @default.
• W2110113876 hasConcept C2779512018 @default.
• W2110113876 hasConcept C61434518 @default.
• W2110113876 hasConcept C71924100 @default.
• W2110113876 hasConceptScore W2110113876C126322002 @default.
• W2110113876 hasConceptScore W2110113876C134018914 @default.
• W2110113876 hasConceptScore W2110113876C2779512018 @default.
• W2110113876 hasConceptScore W2110113876C61434518 @default.
• W2110113876 hasConceptScore W2110113876C71924100 @default.
• W2110113876 hasIssue "10" @default.
• W2110113876 hasLocation W21101138761 @default.
• W2110113876 hasLocation W21101138762 @default.
• W2110113876 hasOpenAccess W2110113876 @default.
• W2110113876 hasPrimaryLocation W21101138761 @default.
• W2110113876 hasRelatedWork W1966504330 @default.
• W2110113876 hasRelatedWork W1979139803 @default.
• W2110113876 hasRelatedWork W2030889776 @default.
• W2110113876 hasRelatedWork W2037631372 @default.
• W2110113876 hasRelatedWork W2040058909 @default.
• W2110113876 hasRelatedWork W2046261096 @default.
• W2110113876 hasRelatedWork W2132898409 @default.
• W2110113876 hasRelatedWork W2385128073 @default.
• W2110113876 hasRelatedWork W2748952813 @default.
• W2110113876 hasRelatedWork W4249176446 @default.
• W2110113876 hasVolume "88" @default.
• W2110113876 isParatext "false" @default.
• W2110113876 isRetracted "false" @default.
• W2110113876 magId "2110113876" @default.
• W2110113876 workType "article" @default.