FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110134512> ?p ?o ?g. }

• W2110134512 endingPage "2122" @default.
• W2110134512 startingPage "2115" @default.
• W2110134512 abstract "Chaetoglobosins are a family of macrocyclic polyketide alkaloids. They possess many similar isomers and exhibit a wide range of biological activities. Thus, there is a need for reliable, fast, and low-cost analysis of this class of compounds.A series of seven chaetoglobosins from Chaetomium globosum, including two types of isomers, were investigated using electrospray ionization quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS) in both positive- and negative-ion mode. The identity of major product ions was supported by deuterium-labeling experiments.In positive-ion mode, the product ion at m/z 130 is the characteristic ion of the indolyl group. A McLafferty rearrangement might play a significant role in the fragmentation of the macrocycle moiety for most chaetoglobosins and produces two series of characteristic product ions, accompanied by neutral losses. The characteristic product ion at m/z 309 in the MS/MS spectrum of chaetoglobosins E indicates the structure of the cyclic olefinic bond in ring B and can be used to distinguish it from the isomers, chaetoglobosins F(ex) , which has an exocyclic double bond on ring B. In negative-ion mode, the McLafferty rearrangement has an important role in the fragmentation pattern of the macrocycle. Some high-abundance radical ions were detected. The radical product ion at m/z 138 might differentiate chaetoglobosins F and penochalasin F, isomers which have very similar structures.In summary, complementary information obtained from fragmentation experiments of [M+H](+) and [M-H](-) precursor ions is especially valuable for rapid identification of chaetoglobosins. The high-abundance radical ions in negative-ion mode are also of scientific interest." @default.
• W2110134512 created "2016-06-24" @default.
• W2110134512 creator A5003113818 @default.
• W2110134512 creator A5023230096 @default.
• W2110134512 creator A5044776527 @default.
• W2110134512 creator A5062817621 @default.
• W2110134512 creator A5066431972 @default.
• W2110134512 creator A5084573973 @default.
• W2110134512 date "2012-08-07" @default.
• W2110134512 modified "2023-10-16" @default.
• W2110134512 title "Electrospray ionization tandem mass spectrometry of chaetoglobosins" @default.
• W2110134512 cites W1975670958 @default.
• W2110134512 cites W1989024717 @default.
• W2110134512 cites W1991933066 @default.
• W2110134512 cites W1995759149 @default.
• W2110134512 cites W1997875627 @default.
• W2110134512 cites W2012324521 @default.
• W2110134512 cites W2013423356 @default.
• W2110134512 cites W2019902127 @default.
• W2110134512 cites W2020668289 @default.
• W2110134512 cites W2026124046 @default.
• W2110134512 cites W2129405305 @default.
• W2110134512 cites W2130772593 @default.
• W2110134512 cites W2144981800 @default.
• W2110134512 cites W2314610754 @default.
• W2110134512 doi "https://doi.org/10.1002/rcm.6329" @default.
• W2110134512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22886807" @default.
• W2110134512 hasPublicationYear "2012" @default.
• W2110134512 type Work @default.
• W2110134512 sameAs 2110134512 @default.
• W2110134512 citedByCount "10" @default.
• W2110134512 countsByYear W21101345122013 @default.
• W2110134512 countsByYear W21101345122014 @default.
• W2110134512 countsByYear W21101345122015 @default.
• W2110134512 countsByYear W21101345122016 @default.
• W2110134512 countsByYear W21101345122018 @default.
• W2110134512 countsByYear W21101345122020 @default.
• W2110134512 countsByYear W21101345122023 @default.
• W2110134512 crossrefType "journal-article" @default.
• W2110134512 hasAuthorship W2110134512A5003113818 @default.
• W2110134512 hasAuthorship W2110134512A5023230096 @default.
• W2110134512 hasAuthorship W2110134512A5044776527 @default.
• W2110134512 hasAuthorship W2110134512A5062817621 @default.
• W2110134512 hasAuthorship W2110134512A5066431972 @default.
• W2110134512 hasAuthorship W2110134512A5084573973 @default.
• W2110134512 hasConcept C111919701 @default.
• W2110134512 hasConcept C113196181 @default.
• W2110134512 hasConcept C145148216 @default.
• W2110134512 hasConcept C162356407 @default.
• W2110134512 hasConcept C178790620 @default.
• W2110134512 hasConcept C185592680 @default.
• W2110134512 hasConcept C191015642 @default.
• W2110134512 hasConcept C194451485 @default.
• W2110134512 hasConcept C198291218 @default.
• W2110134512 hasConcept C205759337 @default.
• W2110134512 hasConcept C31827203 @default.
• W2110134512 hasConcept C40684141 @default.
• W2110134512 hasConcept C41008148 @default.
• W2110134512 hasConcept C43617362 @default.
• W2110134512 hasConcept C66594872 @default.
• W2110134512 hasConcept C68381374 @default.
• W2110134512 hasConcept C71240020 @default.
• W2110134512 hasConceptScore W2110134512C111919701 @default.
• W2110134512 hasConceptScore W2110134512C113196181 @default.
• W2110134512 hasConceptScore W2110134512C145148216 @default.
• W2110134512 hasConceptScore W2110134512C162356407 @default.
• W2110134512 hasConceptScore W2110134512C178790620 @default.
• W2110134512 hasConceptScore W2110134512C185592680 @default.
• W2110134512 hasConceptScore W2110134512C191015642 @default.
• W2110134512 hasConceptScore W2110134512C194451485 @default.
• W2110134512 hasConceptScore W2110134512C198291218 @default.
• W2110134512 hasConceptScore W2110134512C205759337 @default.
• W2110134512 hasConceptScore W2110134512C31827203 @default.
• W2110134512 hasConceptScore W2110134512C40684141 @default.
• W2110134512 hasConceptScore W2110134512C41008148 @default.
• W2110134512 hasConceptScore W2110134512C43617362 @default.
• W2110134512 hasConceptScore W2110134512C66594872 @default.
• W2110134512 hasConceptScore W2110134512C68381374 @default.
• W2110134512 hasConceptScore W2110134512C71240020 @default.
• W2110134512 hasIssue "18" @default.
• W2110134512 hasLocation W21101345121 @default.
• W2110134512 hasLocation W21101345122 @default.
• W2110134512 hasOpenAccess W2110134512 @default.
• W2110134512 hasPrimaryLocation W21101345121 @default.
• W2110134512 hasRelatedWork W1982309303 @default.
• W2110134512 hasRelatedWork W2048957204 @default.
• W2110134512 hasRelatedWork W2052286016 @default.
• W2110134512 hasRelatedWork W2063819904 @default.
• W2110134512 hasRelatedWork W2078110256 @default.
• W2110134512 hasRelatedWork W2110962247 @default.
• W2110134512 hasRelatedWork W2152259552 @default.
• W2110134512 hasRelatedWork W2383324877 @default.
• W2110134512 hasRelatedWork W2540665996 @default.
• W2110134512 hasRelatedWork W4249823562 @default.
• W2110134512 hasVolume "26" @default.
• W2110134512 isParatext "false" @default.
• W2110134512 isRetracted "false" @default.
• W2110134512 magId "2110134512" @default.

• next