FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110135152> ?p ?o ?g. }

• W2110135152 endingPage "G822" @default.
• W2110135152 startingPage "G816" @default.
• W2110135152 abstract "Water transport across gallbladder epithelium is driven by osmotic gradients generated from active salt absorption and secretion. Aquaporin (AQP) water channels have been proposed to facilitate transepithelial water transport in gallbladder and to modulate bile composition. We found strong AQP1 immunofluorescence at the apical membrane of mouse gallbladder epithelium. Transepithelial osmotic water permeability (Pf) was measured in freshly isolated gallbladder sacs from the kinetics of luminal calcein self-quenching in response to an osmotic gradient. Pf was very high (0.12 cm/s) in gallbladders from wild-type mice, cAMP independent, and independent of osmotic gradient size and direction. Although gallbladders from AQP1 knockout mice had similar size and morphology to those from wild-type mice, their Pf was reduced by approximately 10-fold. Apical plasma membrane water permeability was greatly reduced in AQP1-deficient gallbladders, as measured by cytoplasmic calcein quenching in perfluorocarbon-filled, inverted gallbladder sacs. However, neither bile osmolality nor bile salt concentration differed in gallbladders from wild-type vs. AQP1 knockout mice. Our data indicate constitutively high water permeability in mouse gallbladder epithelium involving transcellular water transport through AQP1. The similar bile salt concentration in gallbladders from AQP1 knockout mice argues against a physiologically important role for AQP1 in mouse gallbladder." @default.
• W2110135152 created "2016-06-24" @default.
• W2110135152 creator A5056450584 @default.
• W2110135152 creator A5065407027 @default.
• W2110135152 creator A5072978671 @default.
• W2110135152 creator A5076042378 @default.
• W2110135152 date "2009-04-01" @default.
• W2110135152 modified "2023-10-02" @default.
• W2110135152 title "Very high aquaporin-1 facilitated water permeability in mouse gallbladder" @default.
• W2110135152 cites W1828300760 @default.
• W2110135152 cites W1852199856 @default.
• W2110135152 cites W1963744131 @default.
• W2110135152 cites W1966343932 @default.
• W2110135152 cites W1970929493 @default.
• W2110135152 cites W1974169246 @default.
• W2110135152 cites W1978610957 @default.
• W2110135152 cites W1984284559 @default.
• W2110135152 cites W1986177591 @default.
• W2110135152 cites W1986968716 @default.
• W2110135152 cites W1998828079 @default.
• W2110135152 cites W2005078688 @default.
• W2110135152 cites W2005343358 @default.
• W2110135152 cites W2007125874 @default.
• W2110135152 cites W2020099135 @default.
• W2110135152 cites W2020839799 @default.
• W2110135152 cites W2032482731 @default.
• W2110135152 cites W2041178268 @default.
• W2110135152 cites W2042577267 @default.
• W2110135152 cites W2045611996 @default.
• W2110135152 cites W2046611979 @default.
• W2110135152 cites W2068767062 @default.
• W2110135152 cites W2072251236 @default.
• W2110135152 cites W2084179773 @default.
• W2110135152 cites W2092193387 @default.
• W2110135152 cites W2096526128 @default.
• W2110135152 cites W2108169177 @default.
• W2110135152 cites W2110059758 @default.
• W2110135152 cites W2110790128 @default.
• W2110135152 cites W2115956096 @default.
• W2110135152 cites W2137671217 @default.
• W2110135152 cites W2138651864 @default.
• W2110135152 cites W2150634827 @default.
• W2110135152 cites W2167347790 @default.
• W2110135152 cites W2334838478 @default.
• W2110135152 cites W54418235 @default.
• W2110135152 doi "https://doi.org/10.1152/ajpgi.90680.2008" @default.
• W2110135152 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2670675" @default.
• W2110135152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19179619" @default.
• W2110135152 hasPublicationYear "2009" @default.
• W2110135152 type Work @default.
• W2110135152 sameAs 2110135152 @default.
• W2110135152 citedByCount "26" @default.
• W2110135152 countsByYear W21101351522012 @default.
• W2110135152 countsByYear W21101351522013 @default.
• W2110135152 countsByYear W21101351522014 @default.
• W2110135152 countsByYear W21101351522015 @default.
• W2110135152 countsByYear W21101351522016 @default.
• W2110135152 countsByYear W21101351522017 @default.
• W2110135152 countsByYear W21101351522018 @default.
• W2110135152 countsByYear W21101351522019 @default.
• W2110135152 countsByYear W21101351522022 @default.
• W2110135152 countsByYear W21101351522023 @default.
• W2110135152 crossrefType "journal-article" @default.
• W2110135152 hasAuthorship W2110135152A5056450584 @default.
• W2110135152 hasAuthorship W2110135152A5065407027 @default.
• W2110135152 hasAuthorship W2110135152A5072978671 @default.
• W2110135152 hasAuthorship W2110135152A5076042378 @default.
• W2110135152 hasBestOaLocation W21101351522 @default.
• W2110135152 hasConcept C120882062 @default.
• W2110135152 hasConcept C12554922 @default.
• W2110135152 hasConcept C126322002 @default.
• W2110135152 hasConcept C127413603 @default.
• W2110135152 hasConcept C134018914 @default.
• W2110135152 hasConcept C140737988 @default.
• W2110135152 hasConcept C154280991 @default.
• W2110135152 hasConcept C176285220 @default.
• W2110135152 hasConcept C177586851 @default.
• W2110135152 hasConcept C185592680 @default.
• W2110135152 hasConcept C201289731 @default.
• W2110135152 hasConcept C2775845273 @default.
• W2110135152 hasConcept C2776872141 @default.
• W2110135152 hasConcept C2777148285 @default.
• W2110135152 hasConcept C2988574769 @default.
• W2110135152 hasConcept C2992163139 @default.
• W2110135152 hasConcept C3018436504 @default.
• W2110135152 hasConcept C41625074 @default.
• W2110135152 hasConcept C529295009 @default.
• W2110135152 hasConcept C54355233 @default.
• W2110135152 hasConcept C55493867 @default.
• W2110135152 hasConcept C60903277 @default.
• W2110135152 hasConcept C71924100 @default.
• W2110135152 hasConcept C78519656 @default.
• W2110135152 hasConcept C86803240 @default.
• W2110135152 hasConcept C87717796 @default.
• W2110135152 hasConceptScore W2110135152C120882062 @default.
• W2110135152 hasConceptScore W2110135152C12554922 @default.
• W2110135152 hasConceptScore W2110135152C126322002 @default.
• W2110135152 hasConceptScore W2110135152C127413603 @default.

• next