FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110170849> ?p ?o ?g. }

• W2110170849 endingPage "255" @default.
• W2110170849 startingPage "248" @default.
• W2110170849 abstract "Myocardial perfusion imaging has limited sensitivity for the detection of high-risk coronary artery disease (CAD). We tested the hypothesis that a normal coronary flow reserve (CFR) would be helpful for excluding the presence of high-risk CAD on angiography. <b>Methods:</b> We studied 290 consecutive patients undergoing ⁸²Rb PET within 180 d of invasive coronary angiography. High-risk CAD on angiography was defined as 2-vessel disease (≥70% stenosis), including the proximal left anterior descending artery; 3-vessel disease; or left main CAD (≥50% stenosis). Patients with prior Q wave myocardial infarction, elevated troponin levels between studies, prior coronary artery bypass grafting, a left ventricular ejection fraction of less than 40%, or severe valvular heart disease were excluded. <b>Results:</b> Fifty-five patients (19%) had high-risk CAD on angiography. As expected, the trade-off between the sensitivity and the specificity of the CFR for identifying high-risk CAD varied substantially depending on the cutoff selected. In multivariable analysis, a binary CFR of less than or equal to 1.93 provided incremental diagnostic information for the identification of high-risk CAD beyond the model with the Duke clinical risk score (>25%), percentage of left ventricular ischemia (>10%), transient ischemic dilation index (>1.07), and change in the left ventricular ejection fraction during stress (<2) (<i>P</i> = 0.0009). In patients with normal or slightly to moderately abnormal results on perfusion scans (<10% of left ventricular mass) during stress (<i>n</i> = 136), a preserved CFR (>1.93) excluded high-risk CAD with a high sensitivity (86%) and a high negative predictive value (97%). <b>Conclusion:</b> A normal CFR has a high negative predictive value for excluding high-risk CAD on angiography. Although an abnormal CFR increases the probability of significant obstructive CAD, it cannot reliably distinguish significant epicardial stenosis from nonobstructive, diffuse atherosclerosis or microvascular dysfunction." @default.
• W2110170849 created "2016-06-24" @default.
• W2110170849 creator A5004016681 @default.
• W2110170849 creator A5009720934 @default.
• W2110170849 creator A5012676647 @default.
• W2110170849 creator A5040440855 @default.
• W2110170849 creator A5044226573 @default.
• W2110170849 creator A5052617024 @default.
• W2110170849 creator A5052659429 @default.
• W2110170849 creator A5074291947 @default.
• W2110170849 creator A5086342448 @default.
• W2110170849 creator A5087971170 @default.
• W2110170849 creator A5091161722 @default.
• W2110170849 date "2014-01-09" @default.
• W2110170849 modified "2023-10-14" @default.
• W2110170849 title "Preserved Coronary Flow Reserve Effectively Excludes High-Risk Coronary Artery Disease on Angiography" @default.
• W2110170849 cites W1741041 @default.
• W2110170849 cites W1966751875 @default.
• W2110170849 cites W1981606931 @default.
• W2110170849 cites W1984425326 @default.
• W2110170849 cites W1984885280 @default.
• W2110170849 cites W1998868705 @default.
• W2110170849 cites W2003133864 @default.
• W2110170849 cites W2004043464 @default.
• W2110170849 cites W2013897731 @default.
• W2110170849 cites W2014184577 @default.
• W2110170849 cites W2014724702 @default.
• W2110170849 cites W2015409124 @default.
• W2110170849 cites W2016902413 @default.
• W2110170849 cites W2023661512 @default.
• W2110170849 cites W2024931228 @default.
• W2110170849 cites W2030287913 @default.
• W2110170849 cites W2031154758 @default.
• W2110170849 cites W2034147808 @default.
• W2110170849 cites W2037040142 @default.
• W2110170849 cites W2039471471 @default.
• W2110170849 cites W2043137770 @default.
• W2110170849 cites W2054232428 @default.
• W2110170849 cites W2054240708 @default.
• W2110170849 cites W2072454650 @default.
• W2110170849 cites W2088107685 @default.
• W2110170849 cites W2090666862 @default.
• W2110170849 cites W2094078131 @default.
• W2110170849 cites W2102612506 @default.
• W2110170849 cites W2104087352 @default.
• W2110170849 cites W2116107116 @default.
• W2110170849 cites W2119380827 @default.
• W2110170849 cites W2122372991 @default.
• W2110170849 cites W2124144555 @default.
• W2110170849 cites W2133875784 @default.
• W2110170849 cites W2135331997 @default.
• W2110170849 cites W2145164028 @default.
• W2110170849 cites W2154342279 @default.
• W2110170849 cites W2165548906 @default.
• W2110170849 cites W2170493603 @default.
• W2110170849 cites W23573153 @default.
• W2110170849 cites W2939337927 @default.
• W2110170849 doi "https://doi.org/10.2967/jnumed.113.121442" @default.
• W2110170849 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3962818" @default.
• W2110170849 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24408896" @default.
• W2110170849 hasPublicationYear "2014" @default.
• W2110170849 type Work @default.
• W2110170849 sameAs 2110170849 @default.
• W2110170849 citedByCount "200" @default.
• W2110170849 countsByYear W21101708492014 @default.
• W2110170849 countsByYear W21101708492015 @default.
• W2110170849 countsByYear W21101708492016 @default.
• W2110170849 countsByYear W21101708492017 @default.
• W2110170849 countsByYear W21101708492018 @default.
• W2110170849 countsByYear W21101708492019 @default.
• W2110170849 countsByYear W21101708492020 @default.
• W2110170849 countsByYear W21101708492021 @default.
• W2110170849 countsByYear W21101708492022 @default.
• W2110170849 countsByYear W21101708492023 @default.
• W2110170849 crossrefType "journal-article" @default.
• W2110170849 hasAuthorship W2110170849A5004016681 @default.
• W2110170849 hasAuthorship W2110170849A5009720934 @default.
• W2110170849 hasAuthorship W2110170849A5012676647 @default.
• W2110170849 hasAuthorship W2110170849A5040440855 @default.
• W2110170849 hasAuthorship W2110170849A5044226573 @default.
• W2110170849 hasAuthorship W2110170849A5052617024 @default.
• W2110170849 hasAuthorship W2110170849A5052659429 @default.
• W2110170849 hasAuthorship W2110170849A5074291947 @default.
• W2110170849 hasAuthorship W2110170849A5086342448 @default.
• W2110170849 hasAuthorship W2110170849A5087971170 @default.
• W2110170849 hasAuthorship W2110170849A5091161722 @default.
• W2110170849 hasBestOaLocation W21101708491 @default.
• W2110170849 hasConcept C126322002 @default.
• W2110170849 hasConcept C164705383 @default.
• W2110170849 hasConcept C2778198053 @default.
• W2110170849 hasConcept C2778213512 @default.
• W2110170849 hasConcept C2778707443 @default.
• W2110170849 hasConcept C2780007028 @default.
• W2110170849 hasConcept C2780643987 @default.
• W2110170849 hasConcept C500558357 @default.
• W2110170849 hasConcept C71924100 @default.
• W2110170849 hasConcept C78085059 @default.
• W2110170849 hasConceptScore W2110170849C126322002 @default.

• next