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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110177975> ?p ?o ?g. }

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• W2110177975 abstract "An efficient, isocratic high performance liquid chromatography (HPLC) method for determining human immunodeficiency virus (HIV) non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) in plasma is advantageous for laboratories participating in clinical trials and therapeutic drug monitoring (TDM) programs, or conducting small animal research. The combination of isocratic reversed phase chromatography using an S-3, 3.0 mm × 150 mm column along with low plasma volume (200 μl), rapid liquid–liquid extraction, and detection at a single wavelength (212 nm) over a short run time makes this method valuable. Within and between assay variability ranges from 0.8 to 3.5% and 1.2–6.2%, respectively. Accuracy ranges from 91.0 to 112.8% for four quality controls (50, 100, 1000, and 10,000 ng/ml) for all drugs measured (efavirenz, nevirapine, amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir)." @default.
• W2110177975 created "2016-06-24" @default.
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• W2110177975 date "2007-04-01" @default.
• W2110177975 modified "2023-10-17" @default.
• W2110177975 title "An isocratic liquid chromatography method for determining HIV non-nucleoside reverse transcriptase inhibitor and protease inhibitor concentrations in human plasma" @default.
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• W2110177975 doi "https://doi.org/10.1016/j.jchromb.2006.10.022" @default.
• W2110177975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17081812" @default.
• W2110177975 hasPublicationYear "2007" @default.
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