Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110184819> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2110184819 endingPage "109" @default.
- W2110184819 startingPage "105" @default.
- W2110184819 abstract "<b><i>Background:</i></b> Roughly 20-40% of individuals with idiopathic nephrotic syndrome will fail to respond to standard therapies and have a high risk of progression to end stage kidney disease (ESKD). In the last 50 years, no new therapies have been approved specifically for the treatment of these individuals with recalcitrant disease. <b><i>Summary:</i></b> Recent in vitro, translational, and clinical studies have identified novel targets and pathways that not only expand our understanding of the complex pathophysiology of proteinuric disease but also provide an opportunity to challenge the tradition of relying on histologic classification of nephrotic diseases to make treatment decisions. <b><i>Key Messages:</i></b> The traditional methods of directing the care of individuals with nephrotic syndrome by histological classification or deciding second line therapies on the basis of steroid-responsiveness may soon yield customizing therapies based on our expanding understanding of molecular targets. Important non-immunologic mechanisms of widely used immunosuppressive therapies may be just as important in palliating proteinuric disease as proposed immunologic functions." @default.
- W2110184819 created "2016-06-24" @default.
- W2110184819 creator A5000174134 @default.
- W2110184819 creator A5048128579 @default.
- W2110184819 creator A5081944718 @default.
- W2110184819 date "2015-01-01" @default.
- W2110184819 modified "2023-09-26" @default.
- W2110184819 title "Back to the Future: Therapies for Idiopathic Nephrotic Syndrome" @default.
- W2110184819 cites W1977344943 @default.
- W2110184819 cites W1990585494 @default.
- W2110184819 cites W1999719753 @default.
- W2110184819 cites W2008367188 @default.
- W2110184819 cites W2018690710 @default.
- W2110184819 cites W2028212842 @default.
- W2110184819 cites W2032530656 @default.
- W2110184819 cites W2042919464 @default.
- W2110184819 cites W2063694399 @default.
- W2110184819 cites W2076316204 @default.
- W2110184819 cites W2089391563 @default.
- W2110184819 cites W2104602296 @default.
- W2110184819 cites W2110895642 @default.
- W2110184819 cites W2111992695 @default.
- W2110184819 cites W2112653875 @default.
- W2110184819 cites W2112830170 @default.
- W2110184819 cites W2115135526 @default.
- W2110184819 cites W2124215501 @default.
- W2110184819 cites W2129594122 @default.
- W2110184819 cites W2133272865 @default.
- W2110184819 cites W2140164312 @default.
- W2110184819 cites W2143078493 @default.
- W2110184819 cites W2144479843 @default.
- W2110184819 cites W2146965144 @default.
- W2110184819 cites W2150460695 @default.
- W2110184819 cites W2154765205 @default.
- W2110184819 cites W2155329876 @default.
- W2110184819 cites W2323753285 @default.
- W2110184819 doi "https://doi.org/10.1159/000368951" @default.
- W2110184819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25659288" @default.
- W2110184819 hasPublicationYear "2015" @default.
- W2110184819 type Work @default.
- W2110184819 sameAs 2110184819 @default.
- W2110184819 citedByCount "3" @default.
- W2110184819 countsByYear W21101848192016 @default.
- W2110184819 countsByYear W21101848192018 @default.
- W2110184819 countsByYear W21101848192023 @default.
- W2110184819 crossrefType "journal-article" @default.
- W2110184819 hasAuthorship W2110184819A5000174134 @default.
- W2110184819 hasAuthorship W2110184819A5048128579 @default.
- W2110184819 hasAuthorship W2110184819A5081944718 @default.
- W2110184819 hasBestOaLocation W21101848191 @default.
- W2110184819 hasConcept C10162356 @default.
- W2110184819 hasConcept C126322002 @default.
- W2110184819 hasConcept C203014093 @default.
- W2110184819 hasConcept C2778653478 @default.
- W2110184819 hasConcept C2778930706 @default.
- W2110184819 hasConcept C2779134260 @default.
- W2110184819 hasConcept C60644358 @default.
- W2110184819 hasConcept C71924100 @default.
- W2110184819 hasConcept C86803240 @default.
- W2110184819 hasConceptScore W2110184819C10162356 @default.
- W2110184819 hasConceptScore W2110184819C126322002 @default.
- W2110184819 hasConceptScore W2110184819C203014093 @default.
- W2110184819 hasConceptScore W2110184819C2778653478 @default.
- W2110184819 hasConceptScore W2110184819C2778930706 @default.
- W2110184819 hasConceptScore W2110184819C2779134260 @default.
- W2110184819 hasConceptScore W2110184819C60644358 @default.
- W2110184819 hasConceptScore W2110184819C71924100 @default.
- W2110184819 hasConceptScore W2110184819C86803240 @default.
- W2110184819 hasIssue "1-3" @default.
- W2110184819 hasLocation W21101848191 @default.
- W2110184819 hasLocation W21101848192 @default.
- W2110184819 hasOpenAccess W2110184819 @default.
- W2110184819 hasPrimaryLocation W21101848191 @default.
- W2110184819 hasRelatedWork W2088525243 @default.
- W2110184819 hasRelatedWork W2139521168 @default.
- W2110184819 hasRelatedWork W2413726396 @default.
- W2110184819 hasRelatedWork W2765282288 @default.
- W2110184819 hasRelatedWork W2888779279 @default.
- W2110184819 hasRelatedWork W2970997773 @default.
- W2110184819 hasRelatedWork W3000739855 @default.
- W2110184819 hasRelatedWork W3042521120 @default.
- W2110184819 hasRelatedWork W3200815141 @default.
- W2110184819 hasRelatedWork W4200511119 @default.
- W2110184819 hasVolume "39" @default.
- W2110184819 isParatext "false" @default.
- W2110184819 isRetracted "false" @default.
- W2110184819 magId "2110184819" @default.
- W2110184819 workType "article" @default.