FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110185074> ?p ?o ?g. }

• W2110185074 endingPage "638" @default.
• W2110185074 startingPage "632" @default.
• W2110185074 abstract "Background: The development of alcohol dependence (AD) involves transitions through multiple stages of drinking behaviors and is shaped by both heritable and environmental influences. We attempted to capture this dynamic process by characterizing genetic and environmental contributions to the rate at which women progressed through 3 significant transitions along the pathway to AD: nonuse to initiation, initiation to onset of first alcohol-related problem, and first problem to onset of AD. Methods: The sample consisted of 3,546 female twins from the Missouri Adolescent Female Twin Study. Participants ranged in age from 18 to 29 years. Retrospective reports of alcohol use histories were collected by telephone diagnostic interview and transition times between drinking milestones were coded ordinally. Standard genetic analyses were conducted in Mx to derive a trivariate model that provided estimates of genetic and environmental influences that were common as well as specific to the 3 transition times. Results: Heritable influences were found for rate of progression across all 3 transitions, accounting for 30 to 47% of the variance in transition times. Shared environmental contributions were evident only in rate of progression from nonuse to initiation (i.e., age at first drink). Heritable contributions to the rate of movement through successive drinking milestones were attributable to a common factor, whereas environmental influences were transition-specific. Conclusions: The current study is unique in its use of a genetically informative design to document the rate of movement between drinking milestones in a female sample and to examine genetic contributions to multiple transition times over the course of AD development. Results indicate that an earlier report of heritability for males in rate of progression from regular drinking to AD generalizes to women and to other alcohol stage transitions. Findings also suggest the need to consider stage-specific environmental contributions to alcohol outcomes in developing interventions." @default.
• W2110185074 created "2016-06-24" @default.
• W2110185074 creator A5010113450 @default.
• W2110185074 creator A5010399208 @default.
• W2110185074 creator A5016028146 @default.
• W2110185074 creator A5034870861 @default.
• W2110185074 creator A5042130650 @default.
• W2110185074 date "2008-04-01" @default.
• W2110185074 modified "2023-10-16" @default.
• W2110185074 title "Genetic and Environmental Influences on the Rate of Progression to Alcohol Dependence in Young Women" @default.
• W2110185074 cites W170083426 @default.
• W2110185074 cites W1968818592 @default.
• W2110185074 cites W1977541535 @default.
• W2110185074 cites W1982185635 @default.
• W2110185074 cites W1982615438 @default.
• W2110185074 cites W1991059973 @default.
• W2110185074 cites W1994978449 @default.
• W2110185074 cites W1996172010 @default.
• W2110185074 cites W2003119475 @default.
• W2110185074 cites W2005821863 @default.
• W2110185074 cites W2006999172 @default.
• W2110185074 cites W2014450015 @default.
• W2110185074 cites W2023517148 @default.
• W2110185074 cites W2040790125 @default.
• W2110185074 cites W2040893718 @default.
• W2110185074 cites W2058136899 @default.
• W2110185074 cites W2060008533 @default.
• W2110185074 cites W2063066789 @default.
• W2110185074 cites W2068287526 @default.
• W2110185074 cites W2068636462 @default.
• W2110185074 cites W2069793642 @default.
• W2110185074 cites W2071835910 @default.
• W2110185074 cites W2074542832 @default.
• W2110185074 cites W2085143064 @default.
• W2110185074 cites W2096497994 @default.
• W2110185074 cites W2108424110 @default.
• W2110185074 cites W2109980915 @default.
• W2110185074 cites W2110962477 @default.
• W2110185074 cites W2116806046 @default.
• W2110185074 cites W2117205474 @default.
• W2110185074 cites W2121718091 @default.
• W2110185074 cites W2125455220 @default.
• W2110185074 cites W2136450741 @default.
• W2110185074 cites W2141146828 @default.
• W2110185074 doi "https://doi.org/10.1111/j.1530-0277.2008.00621.x" @default.
• W2110185074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3593341" @default.
• W2110185074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18331380" @default.
• W2110185074 hasPublicationYear "2008" @default.
• W2110185074 type Work @default.
• W2110185074 sameAs 2110185074 @default.
• W2110185074 citedByCount "28" @default.
• W2110185074 countsByYear W21101850742012 @default.
• W2110185074 countsByYear W21101850742013 @default.
• W2110185074 countsByYear W21101850742014 @default.
• W2110185074 countsByYear W21101850742015 @default.
• W2110185074 countsByYear W21101850742016 @default.
• W2110185074 countsByYear W21101850742017 @default.
• W2110185074 countsByYear W21101850742018 @default.
• W2110185074 countsByYear W21101850742021 @default.
• W2110185074 countsByYear W21101850742022 @default.
• W2110185074 crossrefType "journal-article" @default.
• W2110185074 hasAuthorship W2110185074A5010113450 @default.
• W2110185074 hasAuthorship W2110185074A5010399208 @default.
• W2110185074 hasAuthorship W2110185074A5016028146 @default.
• W2110185074 hasAuthorship W2110185074A5034870861 @default.
• W2110185074 hasAuthorship W2110185074A5042130650 @default.
• W2110185074 hasBestOaLocation W21101850742 @default.
• W2110185074 hasConcept C138496976 @default.
• W2110185074 hasConcept C144024400 @default.
• W2110185074 hasConcept C149923435 @default.
• W2110185074 hasConcept C15744967 @default.
• W2110185074 hasConcept C161890455 @default.
• W2110185074 hasConcept C169594400 @default.
• W2110185074 hasConcept C2779436514 @default.
• W2110185074 hasConcept C2781066024 @default.
• W2110185074 hasConcept C54355233 @default.
• W2110185074 hasConcept C55493867 @default.
• W2110185074 hasConcept C71924100 @default.
• W2110185074 hasConcept C86803240 @default.
• W2110185074 hasConceptScore W2110185074C138496976 @default.
• W2110185074 hasConceptScore W2110185074C144024400 @default.
• W2110185074 hasConceptScore W2110185074C149923435 @default.
• W2110185074 hasConceptScore W2110185074C15744967 @default.
• W2110185074 hasConceptScore W2110185074C161890455 @default.
• W2110185074 hasConceptScore W2110185074C169594400 @default.
• W2110185074 hasConceptScore W2110185074C2779436514 @default.
• W2110185074 hasConceptScore W2110185074C2781066024 @default.
• W2110185074 hasConceptScore W2110185074C54355233 @default.
• W2110185074 hasConceptScore W2110185074C55493867 @default.
• W2110185074 hasConceptScore W2110185074C71924100 @default.
• W2110185074 hasConceptScore W2110185074C86803240 @default.
• W2110185074 hasIssue "4" @default.
• W2110185074 hasLocation W21101850741 @default.
• W2110185074 hasLocation W21101850742 @default.
• W2110185074 hasLocation W21101850743 @default.
• W2110185074 hasLocation W21101850744 @default.
• W2110185074 hasOpenAccess W2110185074 @default.
• W2110185074 hasPrimaryLocation W21101850741 @default.

• next