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- W2110207825 endingPage "1586" @default.
- W2110207825 startingPage "1567" @default.
- W2110207825 abstract "Helminths are parasitic organisms that can be broadly described as worms due to their elongated body plan, but which otherwise differ in shape, development, migratory routes and the predilection site of the adults and larvae. They are divided into three major groups: trematodes (flukes), which are leaf-shaped, hermaphroditic (except for blood flukes) flatworms with oral and ventral suckers; cestodes (tapeworms), which are segmented, hermaphroditic flatworms that inhabit the intestinal lumen; and nematodes (roundworms), which are dioecious, cylindrical parasites that inhabit intestinal and peripheral tissue sites. Helminths exhibit a sublime co-evolution with the host's immune system that has enabled them to successfully colonize almost all multicellular species present in every geographical environment, including over two billion humans. In the face of this challenge, the host immune system has evolved to strike a delicate balance between attempts to neutralize the infectious assault versus limitation of damage to host tissues. Among the most important cell types during helminthic invasion are granulocytes: eosinophils, neutrophils and basophils. Depending on the specific context, these leukocytes may have pivotal roles in host protection, immunopathology, or facilitation of helminth establishment. This review provides an overview of the function of granulocytes in helminthic infections." @default.
- W2110207825 created "2016-06-24" @default.
- W2110207825 creator A5052953199 @default.
- W2110207825 creator A5066054917 @default.
- W2110207825 creator A5067632899 @default.
- W2110207825 creator A5078813273 @default.
- W2110207825 date "2012-04-04" @default.
- W2110207825 modified "2023-10-14" @default.
- W2110207825 title "Granulocytes in Helminth Infection - Who is Calling the Shots?" @default.
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