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- W2110222743 abstract "Many pieces of evidence such as the seasonal variation in allergic symptoms with the rhythm of plant pollination suggest that plants are one of the most probable causes of allergy, therefore, the aim of this study was to evaluate of the allergenicity effect of Artemisia deserti flowering taps extract. In this research, flowering taps of Artemisia deserti were collected from Isfahan around, Iran in September 2012. Flowering taps were extracted using phosphate-buffered saline, PH 7.4. Three concentrations of extracts (5%, 10%, 15%) were prepared. The experiments were intraperitoneally injection of the extracts 3 times, once every 10 days. In this research the flowering taps allergenicity were detected using subcutaneous, serological and clinical tests. Tests were done on Hartley male Guinea pigs. In treated and control groups the appearance of wheal, their diameter, serum IgE, eosinophilia, neutrophilia were compared. Dates were analyzed using ANOVA test in the p <0.05. During the skin test, the allergenic sensitivity was observed for 10% phosphate-buffered saline extracts, with an average wheal diameter of about 2 cm. There are significant changes of allergenicity effects between treatment samples and control samples (P<0.05). Results of blood smears were seen that, the numbers of eosinophils, neutrophils and amount of IgE were increased in the treated animals with extracts comparing control groups. The results are shown that the higher allergenicity of 10% extract due to the presence of allergenicity proteins." @default.
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- W2110222743 date "2013-01-01" @default.
- W2110222743 modified "2023-09-24" @default.
- W2110222743 title "A Study on the Allergenicity of Artemisia Deserti Flowering Taps in Guinea pigs" @default.
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