FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110228168> ?p ?o ?g. }

• W2110228168 endingPage "188" @default.
• W2110228168 startingPage "180" @default.
• W2110228168 abstract "Abstract Immunohistochemisty with RD3, a monoclonal antibody specific for three‐repeat (3R) tau, is sometimes hampered by diffuse neuronal staining on formalin‐fixed, paraffin‐embedded sections pretreated with formic acid and heating. Additional pretreatment with potassium permanganate followed by oxalic acid completely eliminated this diffuse RD3‐immunoreactivity (IR) in neurons. Furthermore, this additional pretreatment uniformly enhanced RD3‐IR, as well as RD4‐IR, a monoclonal antibody specific for four‐repeat (4R) tau, on pathological deposits with tau IR. This enhanced sensitivity and specificity may allow more reliable identification of 3R and 4R tau in pathological deposits, which may be variable dependent on disease and regions. Cerebral cortex and midbrain from 8 patients [5 progressive supranuclear palsy (PSP) and 3 corticobasal degeneration (CBD)] were screened for RD3‐ and RD4‐IR with this improved procedure. In addition to RD4‐positive structures found both in cerebral cortex and brainstem, RD3‐positive neurofibrillary tangles (NFTs) were also found in midbrain in 7 of these 8 cases but not in the cortex. Multi‐labeling study demonstrated that most of RD3‐negative neurons were positive for RD4. This reliable demonstration of pathological 3R tau deposits in the brainstem of PSP/CBD, so far presumably characterized by deposition of 4R tau, is useful to map tau‐positive lesions according to their biochemical composition." @default.
• W2110228168 created "2016-06-24" @default.
• W2110228168 creator A5000336771 @default.
• W2110228168 creator A5026265994 @default.
• W2110228168 creator A5074486947 @default.
• W2110228168 creator A5085027104 @default.
• W2110228168 date "2010-09-06" @default.
• W2110228168 modified "2023-10-17" @default.
• W2110228168 title "Specific Detection of Pathological Three-repeat Tau after Pretreatment with Potassium Permanganate and Oxalic Acid in PSP/CBD Brains" @default.
• W2110228168 cites W1980304507 @default.
• W2110228168 cites W1991918797 @default.
• W2110228168 cites W2005599605 @default.
• W2110228168 cites W2010751802 @default.
• W2110228168 cites W2015563160 @default.
• W2110228168 cites W2030992643 @default.
• W2110228168 cites W2035318781 @default.
• W2110228168 cites W2043503682 @default.
• W2110228168 cites W2055932724 @default.
• W2110228168 cites W2059848978 @default.
• W2110228168 cites W2078871949 @default.
• W2110228168 cites W2093650784 @default.
• W2110228168 cites W2094697116 @default.
• W2110228168 cites W2094826609 @default.
• W2110228168 cites W2129951633 @default.
• W2110228168 cites W2137301167 @default.
• W2110228168 cites W2168396089 @default.
• W2110228168 cites W2170906442 @default.
• W2110228168 cites W2400693235 @default.
• W2110228168 doi "https://doi.org/10.1111/j.1750-3639.2010.00433.x" @default.
• W2110228168 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8094262" @default.
• W2110228168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20825412" @default.
• W2110228168 hasPublicationYear "2010" @default.
• W2110228168 type Work @default.
• W2110228168 sameAs 2110228168 @default.
• W2110228168 citedByCount "31" @default.
• W2110228168 countsByYear W21102281682012 @default.
• W2110228168 countsByYear W21102281682013 @default.
• W2110228168 countsByYear W21102281682014 @default.
• W2110228168 countsByYear W21102281682015 @default.
• W2110228168 countsByYear W21102281682016 @default.
• W2110228168 countsByYear W21102281682017 @default.
• W2110228168 countsByYear W21102281682018 @default.
• W2110228168 countsByYear W21102281682019 @default.
• W2110228168 countsByYear W21102281682020 @default.
• W2110228168 countsByYear W21102281682021 @default.
• W2110228168 countsByYear W21102281682022 @default.
• W2110228168 crossrefType "journal-article" @default.
• W2110228168 hasAuthorship W2110228168A5000336771 @default.
• W2110228168 hasAuthorship W2110228168A5026265994 @default.
• W2110228168 hasAuthorship W2110228168A5074486947 @default.
• W2110228168 hasAuthorship W2110228168A5085027104 @default.
• W2110228168 hasBestOaLocation W21102281682 @default.
• W2110228168 hasConcept C142724271 @default.
• W2110228168 hasConcept C15744967 @default.
• W2110228168 hasConcept C169760540 @default.
• W2110228168 hasConcept C185592680 @default.
• W2110228168 hasConcept C2776477761 @default.
• W2110228168 hasConcept C2777348757 @default.
• W2110228168 hasConcept C2778670691 @default.
• W2110228168 hasConcept C2779134260 @default.
• W2110228168 hasConcept C2781041448 @default.
• W2110228168 hasConcept C2781172350 @default.
• W2110228168 hasConcept C2781346138 @default.
• W2110228168 hasConcept C502032728 @default.
• W2110228168 hasConcept C551621295 @default.
• W2110228168 hasConcept C55493867 @default.
• W2110228168 hasConcept C71924100 @default.
• W2110228168 hasConceptScore W2110228168C142724271 @default.
• W2110228168 hasConceptScore W2110228168C15744967 @default.
• W2110228168 hasConceptScore W2110228168C169760540 @default.
• W2110228168 hasConceptScore W2110228168C185592680 @default.
• W2110228168 hasConceptScore W2110228168C2776477761 @default.
• W2110228168 hasConceptScore W2110228168C2777348757 @default.
• W2110228168 hasConceptScore W2110228168C2778670691 @default.
• W2110228168 hasConceptScore W2110228168C2779134260 @default.
• W2110228168 hasConceptScore W2110228168C2781041448 @default.
• W2110228168 hasConceptScore W2110228168C2781172350 @default.
• W2110228168 hasConceptScore W2110228168C2781346138 @default.
• W2110228168 hasConceptScore W2110228168C502032728 @default.
• W2110228168 hasConceptScore W2110228168C551621295 @default.
• W2110228168 hasConceptScore W2110228168C55493867 @default.
• W2110228168 hasConceptScore W2110228168C71924100 @default.
• W2110228168 hasIssue "2" @default.
• W2110228168 hasLocation W21102281681 @default.
• W2110228168 hasLocation W21102281682 @default.
• W2110228168 hasLocation W21102281683 @default.
• W2110228168 hasOpenAccess W2110228168 @default.
• W2110228168 hasPrimaryLocation W21102281681 @default.
• W2110228168 hasRelatedWork W1968813853 @default.
• W2110228168 hasRelatedWork W2064827607 @default.
• W2110228168 hasRelatedWork W2078800278 @default.
• W2110228168 hasRelatedWork W2111870870 @default.
• W2110228168 hasRelatedWork W2126264983 @default.
• W2110228168 hasRelatedWork W2150803126 @default.
• W2110228168 hasRelatedWork W2154665893 @default.
• W2110228168 hasRelatedWork W2171660142 @default.
• W2110228168 hasRelatedWork W3215111369 @default.
• W2110228168 hasRelatedWork W4225985870 @default.

• next