Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110254613> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2110254613 startingPage "1756" @default.
- W2110254613 abstract "Introduction: In recent years, heterogeneity of COPD patients has been examined using complex statistical methods (e.g. cluster analyses), which cannot be applied in daily practice.Aims and objectives: To develop simple algorithms allowing for assigning individual COPD patients to COPD phenotypesMethods: 2409 COPD patients were recruited in secondary and tertiary care in France and Belgium. Phenotyping was achieved using factor analysis for mixed data (FAMD) on the following data obtained at inclusion in the study: age, BMI, FEV1, dyspnea (mMRC), exacerbations/yr, presence of cardiovascular disease. Phenotypes were validated using all-cause mortality at three years. Classification and Regression Trees (CARTs) were used for the development of a simple algorithm for assigning individual patients to phenotypes. This algorithm was developed in a random sample representing 66.7% of the population (development cohort) and validated in the remaining 33.3% patients (validation cohort).Results: Cluster analysis identified 5 COPD phenotypes with markedly different rates and age of deaths. In the development cohort CART analysis identified cardiovascular comorbidities, mMRC, FEV1, BMI and age (but not exacerbations) as the key variables for determining rates and age of death in COPD patients. In the validation cohort, approximately 80% of patients could be assigned to their phenotypes using a simple algorithm based on these variables.Conclusions: The identified algorithm can now be used in other cohorts for external validation. This may represent a step towards a novel classification of COPD." @default.
- W2110254613 created "2016-06-24" @default.
- W2110254613 creator A5001192345 @default.
- W2110254613 creator A5012771188 @default.
- W2110254613 creator A5014092783 @default.
- W2110254613 creator A5029939045 @default.
- W2110254613 creator A5046596676 @default.
- W2110254613 creator A5046743106 @default.
- W2110254613 creator A5087522944 @default.
- W2110254613 date "2014-09-01" @default.
- W2110254613 modified "2023-10-17" @default.
- W2110254613 title "Late-breaking abstract: A simple algorithm for assigning individual COPD patients to specific phenotypes" @default.
- W2110254613 hasPublicationYear "2014" @default.
- W2110254613 type Work @default.
- W2110254613 sameAs 2110254613 @default.
- W2110254613 citedByCount "0" @default.
- W2110254613 crossrefType "journal-article" @default.
- W2110254613 hasAuthorship W2110254613A5001192345 @default.
- W2110254613 hasAuthorship W2110254613A5012771188 @default.
- W2110254613 hasAuthorship W2110254613A5014092783 @default.
- W2110254613 hasAuthorship W2110254613A5029939045 @default.
- W2110254613 hasAuthorship W2110254613A5046596676 @default.
- W2110254613 hasAuthorship W2110254613A5046743106 @default.
- W2110254613 hasAuthorship W2110254613A5087522944 @default.
- W2110254613 hasConcept C11413529 @default.
- W2110254613 hasConcept C126322002 @default.
- W2110254613 hasConcept C187212893 @default.
- W2110254613 hasConcept C201903717 @default.
- W2110254613 hasConcept C2776780178 @default.
- W2110254613 hasConcept C2908647359 @default.
- W2110254613 hasConcept C41008148 @default.
- W2110254613 hasConcept C71924100 @default.
- W2110254613 hasConcept C72563966 @default.
- W2110254613 hasConcept C99454951 @default.
- W2110254613 hasConceptScore W2110254613C11413529 @default.
- W2110254613 hasConceptScore W2110254613C126322002 @default.
- W2110254613 hasConceptScore W2110254613C187212893 @default.
- W2110254613 hasConceptScore W2110254613C201903717 @default.
- W2110254613 hasConceptScore W2110254613C2776780178 @default.
- W2110254613 hasConceptScore W2110254613C2908647359 @default.
- W2110254613 hasConceptScore W2110254613C41008148 @default.
- W2110254613 hasConceptScore W2110254613C71924100 @default.
- W2110254613 hasConceptScore W2110254613C72563966 @default.
- W2110254613 hasConceptScore W2110254613C99454951 @default.
- W2110254613 hasOpenAccess W2110254613 @default.
- W2110254613 hasRelatedWork W123372377 @default.
- W2110254613 hasRelatedWork W1598830342 @default.
- W2110254613 hasRelatedWork W1896245104 @default.
- W2110254613 hasRelatedWork W1955814145 @default.
- W2110254613 hasRelatedWork W2087818841 @default.
- W2110254613 hasRelatedWork W2107952444 @default.
- W2110254613 hasRelatedWork W2134422631 @default.
- W2110254613 hasRelatedWork W2138892523 @default.
- W2110254613 hasRelatedWork W2155971227 @default.
- W2110254613 hasRelatedWork W2220526106 @default.
- W2110254613 hasRelatedWork W2550252077 @default.
- W2110254613 hasRelatedWork W2556709515 @default.
- W2110254613 hasRelatedWork W2597054767 @default.
- W2110254613 hasRelatedWork W2642176179 @default.
- W2110254613 hasRelatedWork W2804671783 @default.
- W2110254613 hasRelatedWork W2912911018 @default.
- W2110254613 hasRelatedWork W2991588456 @default.
- W2110254613 hasRelatedWork W3086914752 @default.
- W2110254613 hasRelatedWork W3095266550 @default.
- W2110254613 hasRelatedWork W3155053879 @default.
- W2110254613 hasVolume "44" @default.
- W2110254613 isParatext "false" @default.
- W2110254613 isRetracted "false" @default.
- W2110254613 magId "2110254613" @default.
- W2110254613 workType "article" @default.