FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110257936> ?p ?o ?g. }

• W2110257936 endingPage "883" @default.
• W2110257936 startingPage "877" @default.
• W2110257936 abstract "The Rho—LIM-kinase (LIMK) signaling pathway, believed to be involved in the regulation of tumor invasion, specifically regulates the activity of cofilin. However, it is unclear whether cofilin plays a pivotal role in tumor invasiveness. In this paper we show using a tet-on gene expression system that over-expression of cofilin inhibits the invasiveness of human lung cancer H1299 cells. Over-expressed cofilin disrupts the actin cytoskeleton at the leading edge of the cell and up-regulates p27kip1, which is known to be involved in regulating cell motility. Removal of cofilin over-expression normalizes the p27kip1 level and concomitantly restores the invasiveness of the cultured cells. These findings suggest that excessive cofilin production might prevent cancer cell invasion." @default.
• W2110257936 created "2016-06-24" @default.
• W2110257936 creator A5006604817 @default.
• W2110257936 creator A5041021400 @default.
• W2110257936 creator A5071349371 @default.
• W2110257936 creator A5082401237 @default.
• W2110257936 date "2005-11-01" @default.
• W2110257936 modified "2023-10-16" @default.
• W2110257936 title "Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin" @default.
• W2110257936 cites W1484094963 @default.
• W2110257936 cites W1490646520 @default.
• W2110257936 cites W1640813462 @default.
• W2110257936 cites W1949238489 @default.
• W2110257936 cites W1974574293 @default.
• W2110257936 cites W1988870503 @default.
• W2110257936 cites W1990580084 @default.
• W2110257936 cites W2005744028 @default.
• W2110257936 cites W2007897263 @default.
• W2110257936 cites W2009532293 @default.
• W2110257936 cites W2010779754 @default.
• W2110257936 cites W2017865193 @default.
• W2110257936 cites W2037763774 @default.
• W2110257936 cites W2043385366 @default.
• W2110257936 cites W2055298771 @default.
• W2110257936 cites W2077482758 @default.
• W2110257936 cites W2088649791 @default.
• W2110257936 cites W2088938912 @default.
• W2110257936 cites W2090530471 @default.
• W2110257936 cites W2094494461 @default.
• W2110257936 cites W2100648267 @default.
• W2110257936 cites W2108860858 @default.
• W2110257936 cites W2111613650 @default.
• W2110257936 cites W2115691635 @default.
• W2110257936 cites W2116052541 @default.
• W2110257936 cites W2126546276 @default.
• W2110257936 cites W2131380482 @default.
• W2110257936 cites W2139829576 @default.
• W2110257936 cites W2143073532 @default.
• W2110257936 cites W2161135924 @default.
• W2110257936 cites W2166525118 @default.
• W2110257936 cites W2168534525 @default.
• W2110257936 cites W2417534841 @default.
• W2110257936 cites W2460747984 @default.
• W2110257936 doi "https://doi.org/10.1016/j.cellbi.2005.07.005" @default.
• W2110257936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16301112" @default.
• W2110257936 hasPublicationYear "2005" @default.
• W2110257936 type Work @default.
• W2110257936 sameAs 2110257936 @default.
• W2110257936 citedByCount "28" @default.
• W2110257936 countsByYear W21102579362012 @default.
• W2110257936 countsByYear W21102579362014 @default.
• W2110257936 countsByYear W21102579362015 @default.
• W2110257936 countsByYear W21102579362016 @default.
• W2110257936 countsByYear W21102579362018 @default.
• W2110257936 countsByYear W21102579362019 @default.
• W2110257936 countsByYear W21102579362020 @default.
• W2110257936 countsByYear W21102579362021 @default.
• W2110257936 countsByYear W21102579362022 @default.
• W2110257936 crossrefType "journal-article" @default.
• W2110257936 hasAuthorship W2110257936A5006604817 @default.
• W2110257936 hasAuthorship W2110257936A5041021400 @default.
• W2110257936 hasAuthorship W2110257936A5071349371 @default.
• W2110257936 hasAuthorship W2110257936A5082401237 @default.
• W2110257936 hasConcept C125705527 @default.
• W2110257936 hasConcept C137738243 @default.
• W2110257936 hasConcept C142669718 @default.
• W2110257936 hasConcept C1491633281 @default.
• W2110257936 hasConcept C2776601116 @default.
• W2110257936 hasConcept C2993400109 @default.
• W2110257936 hasConcept C502942594 @default.
• W2110257936 hasConcept C54355233 @default.
• W2110257936 hasConcept C58207958 @default.
• W2110257936 hasConcept C81885089 @default.
• W2110257936 hasConcept C86803240 @default.
• W2110257936 hasConcept C95444343 @default.
• W2110257936 hasConceptScore W2110257936C125705527 @default.
• W2110257936 hasConceptScore W2110257936C137738243 @default.
• W2110257936 hasConceptScore W2110257936C142669718 @default.
• W2110257936 hasConceptScore W2110257936C1491633281 @default.
• W2110257936 hasConceptScore W2110257936C2776601116 @default.
• W2110257936 hasConceptScore W2110257936C2993400109 @default.
• W2110257936 hasConceptScore W2110257936C502942594 @default.
• W2110257936 hasConceptScore W2110257936C54355233 @default.
• W2110257936 hasConceptScore W2110257936C58207958 @default.
• W2110257936 hasConceptScore W2110257936C81885089 @default.
• W2110257936 hasConceptScore W2110257936C86803240 @default.
• W2110257936 hasConceptScore W2110257936C95444343 @default.
• W2110257936 hasIssue "11" @default.
• W2110257936 hasLocation W21102579361 @default.
• W2110257936 hasLocation W21102579362 @default.
• W2110257936 hasOpenAccess W2110257936 @default.
• W2110257936 hasPrimaryLocation W21102579361 @default.
• W2110257936 hasRelatedWork W1989690622 @default.
• W2110257936 hasRelatedWork W2111528037 @default.
• W2110257936 hasRelatedWork W2131939253 @default.
• W2110257936 hasRelatedWork W2137079116 @default.
• W2110257936 hasRelatedWork W2156193902 @default.
• W2110257936 hasRelatedWork W2162411580 @default.

• next