FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110264731> ?p ?o ?g. }

• W2110264731 endingPage "R847" @default.
• W2110264731 startingPage "R840" @default.
• W2110264731 abstract "Vascular conducted responses are believed to play a central role in controlling the microcirculatory blood flow. The responses most likely spread through gap junctions in the vascular wall. At present, four different connexins (Cx) have been detected in the renal vasculature, but their role in transmission of conducted vasoconstrictor signals in the preglomerular arterioles is unknown. Connexin mimetic peptides were previously reported to target and inhibit specific connexins. We, therefore, investigated whether conducted vasoconstriction in isolated renal arterioles could be blocked by the use of mimetic peptides directed against one or more connexins. Preglomerular resistance vessels were microdissected from kidneys of Sprague-Dawley rats and loaded with fura 2. The vessels were stimulated locally by applying electrical current through a micropipette, and the conducted calcium response was measured 500 μm from the site of stimulation. Application of connexin mimetic peptides directed against Cx40, 37/43, 45, or a cocktail with equimolar amounts of each, did not inhibit the propagated response, whereas the nonselective gap junction uncoupler carbenoxolone completely abolished the propagated response. However, the connexin mimetic peptides were able to reduce dye coupling between rat aorta endothelial cells shown to express primarily Cx40. In conclusion, we did not observe any attenuating effects on conducted calcium responses in isolated rat interlobular arteries when exposed to connexin mimetic peptides directed against Cx40, 37/43, or 45. Further studies are needed to determine whether conducted vasoconstriction is mediated via previously undescribed pathways." @default.
• W2110264731 created "2016-06-24" @default.
• W2110264731 creator A5009697773 @default.
• W2110264731 creator A5015097155 @default.
• W2110264731 creator A5064119456 @default.
• W2110264731 creator A5068371728 @default.
• W2110264731 creator A5079962612 @default.
• W2110264731 date "2008-09-01" @default.
• W2110264731 modified "2023-09-23" @default.
• W2110264731 title "Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles" @default.
• W2110264731 cites W111229708 @default.
• W2110264731 cites W1544527487 @default.
• W2110264731 cites W1968402657 @default.
• W2110264731 cites W1974330306 @default.
• W2110264731 cites W1987594610 @default.
• W2110264731 cites W1992086680 @default.
• W2110264731 cites W1995870222 @default.
• W2110264731 cites W2004974355 @default.
• W2110264731 cites W2005817187 @default.
• W2110264731 cites W2017292102 @default.
• W2110264731 cites W2017317688 @default.
• W2110264731 cites W2017324576 @default.
• W2110264731 cites W2019097749 @default.
• W2110264731 cites W2020037363 @default.
• W2110264731 cites W2033162180 @default.
• W2110264731 cites W2034661908 @default.
• W2110264731 cites W2038109343 @default.
• W2110264731 cites W2041854444 @default.
• W2110264731 cites W2049983613 @default.
• W2110264731 cites W2052439504 @default.
• W2110264731 cites W2068859526 @default.
• W2110264731 cites W2071582757 @default.
• W2110264731 cites W2073226037 @default.
• W2110264731 cites W2076989031 @default.
• W2110264731 cites W2079955127 @default.
• W2110264731 cites W2096533721 @default.
• W2110264731 cites W2100565912 @default.
• W2110264731 cites W2101520511 @default.
• W2110264731 cites W2104838758 @default.
• W2110264731 cites W2106092932 @default.
• W2110264731 cites W2111757703 @default.
• W2110264731 cites W2121048488 @default.
• W2110264731 cites W2126811481 @default.
• W2110264731 cites W2134397441 @default.
• W2110264731 cites W2141260882 @default.
• W2110264731 cites W2149991029 @default.
• W2110264731 cites W2167807923 @default.
• W2110264731 cites W2188696810 @default.
• W2110264731 cites W2270452757 @default.
• W2110264731 cites W2315685912 @default.
• W2110264731 cites W2402986453 @default.
• W2110264731 cites W2406778084 @default.
• W2110264731 cites W331519713 @default.
• W2110264731 cites W333268629 @default.
• W2110264731 doi "https://doi.org/10.1152/ajpregu.00491.2007" @default.
• W2110264731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18614765" @default.
• W2110264731 hasPublicationYear "2008" @default.
• W2110264731 type Work @default.
• W2110264731 sameAs 2110264731 @default.
• W2110264731 citedByCount "19" @default.
• W2110264731 countsByYear W21102647312012 @default.
• W2110264731 countsByYear W21102647312013 @default.
• W2110264731 countsByYear W21102647312014 @default.
• W2110264731 countsByYear W21102647312015 @default.
• W2110264731 countsByYear W21102647312016 @default.
• W2110264731 countsByYear W21102647312017 @default.
• W2110264731 countsByYear W21102647312018 @default.
• W2110264731 countsByYear W21102647312021 @default.
• W2110264731 crossrefType "journal-article" @default.
• W2110264731 hasAuthorship W2110264731A5009697773 @default.
• W2110264731 hasAuthorship W2110264731A5015097155 @default.
• W2110264731 hasAuthorship W2110264731A5064119456 @default.
• W2110264731 hasAuthorship W2110264731A5068371728 @default.
• W2110264731 hasAuthorship W2110264731A5079962612 @default.
• W2110264731 hasConcept C120770815 @default.
• W2110264731 hasConcept C126322002 @default.
• W2110264731 hasConcept C134018914 @default.
• W2110264731 hasConcept C158157758 @default.
• W2110264731 hasConcept C181080969 @default.
• W2110264731 hasConcept C185592680 @default.
• W2110264731 hasConcept C24998067 @default.
• W2110264731 hasConcept C2779961880 @default.
• W2110264731 hasConcept C2780228694 @default.
• W2110264731 hasConcept C2780961449 @default.
• W2110264731 hasConcept C519063684 @default.
• W2110264731 hasConcept C71924100 @default.
• W2110264731 hasConcept C79879829 @default.
• W2110264731 hasConcept C86803240 @default.
• W2110264731 hasConcept C95444343 @default.
• W2110264731 hasConceptScore W2110264731C120770815 @default.
• W2110264731 hasConceptScore W2110264731C126322002 @default.
• W2110264731 hasConceptScore W2110264731C134018914 @default.
• W2110264731 hasConceptScore W2110264731C158157758 @default.
• W2110264731 hasConceptScore W2110264731C181080969 @default.
• W2110264731 hasConceptScore W2110264731C185592680 @default.
• W2110264731 hasConceptScore W2110264731C24998067 @default.
• W2110264731 hasConceptScore W2110264731C2779961880 @default.
• W2110264731 hasConceptScore W2110264731C2780228694 @default.

• next