Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110287465> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2110287465 abstract "To evaluate, in a prospective fashion, the clinical interchangeability between two brands of levothyroxine, Synthroid (Boots Pharmaceuticals, Inc., Lincolnshire, Illinois) and Levoxine (Daniels Pharmaceuticals, Inc., St. Petersburg, Florida), by using clinical scores of hyperthyroidism and hypothyroidism, free thyroxine index (FTI), sensitive thyroid-stimulating hormone (TSH), and thyrotropin-releasing hormone (TRH) stimulation testing.Twenty-three of the 31 patients with long-standing primary hypothyroidism (6 men, 25 women; age range 30 to 71 years, mean 47.2 +/- 2.2 SEM) were switched from Synthroid to Levoxine (group 1) and the remaining patients from Levoxine to Synthroid (group 2). After switching, each patient continued to receive the same dosage as previously. Clinical scores of hypothyroidism and hyperthyroidism (Billewicz and Crooks scoring systems, respectively), basal FTI, and TRH stimulation test were obtained before and 4 months after the switching. Comparison of the variables before and after switching was performed separately in each subgroup and in the entire group.There was no statistically significant difference in the hypothyroid clinical scores (-40.1 +/- 1.2 versus -39.7 +/- 1.2), the hyperthyroid clinical scores (-19.6 +/- 0.9 versus -19.2 +/- 1.0), FTI (9.6 +/- 0.3 versus 9.6 +/- 0.3), basal TSH levels (1.4 +/- 0.2 versus 1.4 +/- 0.2 mIU/L), or the magnitude of TSH response to TRH (mean delta TSH 9.4 +/- 1.5 versus 9.2 +/- 1.4 mIU/L), whether the patients were receiving Synthroid or Levoxine.Switching did not result in substantial clinical or laboratory changes in any individual patient. We conclude that the two brands of levothyroxine are clinically interchangeable." @default.
- W2110287465 created "2016-06-24" @default.
- W2110287465 creator A5017150046 @default.
- W2110287465 creator A5042953063 @default.
- W2110287465 creator A5076346437 @default.
- W2110287465 date "1995-04-01" @default.
- W2110287465 modified "2023-09-26" @default.
- W2110287465 title "Assessment of interchangeability of two brands of levothyroxine preparations with a third-generation TSH assay" @default.
- W2110287465 cites W1976274614 @default.
- W2110287465 cites W1989420386 @default.
- W2110287465 cites W1993952876 @default.
- W2110287465 cites W1994530252 @default.
- W2110287465 cites W2006117703 @default.
- W2110287465 cites W2007840979 @default.
- W2110287465 cites W2017179329 @default.
- W2110287465 cites W2022517313 @default.
- W2110287465 cites W2033508223 @default.
- W2110287465 cites W2035510928 @default.
- W2110287465 cites W2037749749 @default.
- W2110287465 cites W2038071707 @default.
- W2110287465 cites W2052381481 @default.
- W2110287465 cites W2057365954 @default.
- W2110287465 cites W2071476264 @default.
- W2110287465 cites W2072298781 @default.
- W2110287465 cites W2079010724 @default.
- W2110287465 cites W2087975771 @default.
- W2110287465 cites W2324164337 @default.
- W2110287465 cites W2354581373 @default.
- W2110287465 cites W2378294549 @default.
- W2110287465 doi "https://doi.org/10.1016/s0002-9343(99)80316-7" @default.
- W2110287465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7709950" @default.
- W2110287465 hasPublicationYear "1995" @default.
- W2110287465 type Work @default.
- W2110287465 sameAs 2110287465 @default.
- W2110287465 citedByCount "25" @default.
- W2110287465 countsByYear W21102874652012 @default.
- W2110287465 countsByYear W21102874652013 @default.
- W2110287465 countsByYear W21102874652014 @default.
- W2110287465 countsByYear W21102874652015 @default.
- W2110287465 countsByYear W21102874652016 @default.
- W2110287465 countsByYear W21102874652019 @default.
- W2110287465 countsByYear W21102874652021 @default.
- W2110287465 crossrefType "journal-article" @default.
- W2110287465 hasAuthorship W2110287465A5017150046 @default.
- W2110287465 hasAuthorship W2110287465A5042953063 @default.
- W2110287465 hasAuthorship W2110287465A5076346437 @default.
- W2110287465 hasConcept C126322002 @default.
- W2110287465 hasConcept C134018914 @default.
- W2110287465 hasConcept C199360897 @default.
- W2110287465 hasConcept C24998067 @default.
- W2110287465 hasConcept C2775883008 @default.
- W2110287465 hasConcept C2776216936 @default.
- W2110287465 hasConcept C2777886399 @default.
- W2110287465 hasConcept C2778024521 @default.
- W2110287465 hasConcept C2779306644 @default.
- W2110287465 hasConcept C2779606619 @default.
- W2110287465 hasConcept C41008148 @default.
- W2110287465 hasConcept C526584372 @default.
- W2110287465 hasConcept C71315377 @default.
- W2110287465 hasConcept C71924100 @default.
- W2110287465 hasConcept C90924648 @default.
- W2110287465 hasConceptScore W2110287465C126322002 @default.
- W2110287465 hasConceptScore W2110287465C134018914 @default.
- W2110287465 hasConceptScore W2110287465C199360897 @default.
- W2110287465 hasConceptScore W2110287465C24998067 @default.
- W2110287465 hasConceptScore W2110287465C2775883008 @default.
- W2110287465 hasConceptScore W2110287465C2776216936 @default.
- W2110287465 hasConceptScore W2110287465C2777886399 @default.
- W2110287465 hasConceptScore W2110287465C2778024521 @default.
- W2110287465 hasConceptScore W2110287465C2779306644 @default.
- W2110287465 hasConceptScore W2110287465C2779606619 @default.
- W2110287465 hasConceptScore W2110287465C41008148 @default.
- W2110287465 hasConceptScore W2110287465C526584372 @default.
- W2110287465 hasConceptScore W2110287465C71315377 @default.
- W2110287465 hasConceptScore W2110287465C71924100 @default.
- W2110287465 hasConceptScore W2110287465C90924648 @default.
- W2110287465 hasLocation W21102874651 @default.
- W2110287465 hasLocation W21102874652 @default.
- W2110287465 hasOpenAccess W2110287465 @default.
- W2110287465 hasPrimaryLocation W21102874651 @default.
- W2110287465 hasRelatedWork W2016437206 @default.
- W2110287465 hasRelatedWork W2025216813 @default.
- W2110287465 hasRelatedWork W2039441029 @default.
- W2110287465 hasRelatedWork W2049335971 @default.
- W2110287465 hasRelatedWork W2070410104 @default.
- W2110287465 hasRelatedWork W2085386259 @default.
- W2110287465 hasRelatedWork W2088632221 @default.
- W2110287465 hasRelatedWork W2089926309 @default.
- W2110287465 hasRelatedWork W2148458830 @default.
- W2110287465 hasRelatedWork W2325997963 @default.
- W2110287465 isParatext "false" @default.
- W2110287465 isRetracted "false" @default.
- W2110287465 magId "2110287465" @default.
- W2110287465 workType "article" @default.