FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110298924> ?p ?o ?g. }

• W2110298924 abstract "Abstract Background Platinum derivatives are used widely for the treatment of many cancers. However, the toxicity that is observed makes imperative the need for new drugs, or new combinations. Anvirzel™ is an extract which has been demonstrated with experimental data that displays anticancer activity. The aim of the present study is to determine whether the combination of Cisplatin and Anvirzel™ has a synergistic effect against different types of cancer. Materials and methods To measure the efficacy of treatment with Cisplatin and Anvirzel™, methyl-tetrazolium dye (MTT) chemosensitivity assays were used incorporating established human cancer cell lines. Measurements were performed in triplicates, three times, using different incubation times and different concentrations of the two formulations in combination or on their own. t-test was used for statistical analysis. Results In the majority of the cell lines tested, lower concentrations of Anvirzel™ induced a synergistic effect when combined with low concentrations of Cisplatin after an incubation period of 48 to 72 h. The combination of Anvirzel™/Cisplatin showed anti-proliferative effects against a wide range of tumours. Conclusion The results showed that the combination of Anvirzel™ and Cisplatin is more effective than monotherapy, even when administered at low concentrations; thus, undesirable toxic effects can be avoided." @default.
• W2110298924 created "2016-06-24" @default.
• W2110298924 creator A5001267488 @default.
• W2110298924 creator A5012341029 @default.
• W2110298924 creator A5023138603 @default.
• W2110298924 creator A5042415460 @default.
• W2110298924 creator A5047541453 @default.
• W2110298924 creator A5049362787 @default.
• W2110298924 creator A5057888085 @default.
• W2110298924 creator A5080380436 @default.
• W2110298924 date "2013-03-25" @default.
• W2110298924 modified "2023-10-16" @default.
• W2110298924 title "Anvirzel™ in combination with cisplatin in breast, colon, lung, prostate, melanoma and pancreatic cancer cell lines" @default.
• W2110298924 cites W1534187989 @default.
• W2110298924 cites W1587138655 @default.
• W2110298924 cites W1976686960 @default.
• W2110298924 cites W1980463323 @default.
• W2110298924 cites W1993138981 @default.
• W2110298924 cites W1993943341 @default.
• W2110298924 cites W1994647246 @default.
• W2110298924 cites W1997767294 @default.
• W2110298924 cites W1999550609 @default.
• W2110298924 cites W2000366627 @default.
• W2110298924 cites W2012108057 @default.
• W2110298924 cites W2012479775 @default.
• W2110298924 cites W2018741186 @default.
• W2110298924 cites W2037678485 @default.
• W2110298924 cites W2039425889 @default.
• W2110298924 cites W2047199285 @default.
• W2110298924 cites W2069034973 @default.
• W2110298924 cites W2114918609 @default.
• W2110298924 cites W2172287945 @default.
• W2110298924 cites W2330914448 @default.
• W2110298924 cites W4250436576 @default.
• W2110298924 cites W55744857 @default.
• W2110298924 doi "https://doi.org/10.1186/2050-6511-14-18" @default.
• W2110298924 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3637172" @default.
• W2110298924 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23521834" @default.
• W2110298924 hasPublicationYear "2013" @default.
• W2110298924 type Work @default.
• W2110298924 sameAs 2110298924 @default.
• W2110298924 citedByCount "28" @default.
• W2110298924 countsByYear W21102989242013 @default.
• W2110298924 countsByYear W21102989242014 @default.
• W2110298924 countsByYear W21102989242015 @default.
• W2110298924 countsByYear W21102989242016 @default.
• W2110298924 countsByYear W21102989242017 @default.
• W2110298924 countsByYear W21102989242018 @default.
• W2110298924 countsByYear W21102989242019 @default.
• W2110298924 countsByYear W21102989242020 @default.
• W2110298924 countsByYear W21102989242021 @default.
• W2110298924 countsByYear W21102989242022 @default.
• W2110298924 countsByYear W21102989242023 @default.
• W2110298924 crossrefType "journal-article" @default.
• W2110298924 hasAuthorship W2110298924A5001267488 @default.
• W2110298924 hasAuthorship W2110298924A5012341029 @default.
• W2110298924 hasAuthorship W2110298924A5023138603 @default.
• W2110298924 hasAuthorship W2110298924A5042415460 @default.
• W2110298924 hasAuthorship W2110298924A5047541453 @default.
• W2110298924 hasAuthorship W2110298924A5049362787 @default.
• W2110298924 hasAuthorship W2110298924A5057888085 @default.
• W2110298924 hasAuthorship W2110298924A5080380436 @default.
• W2110298924 hasBestOaLocation W21102989241 @default.
• W2110298924 hasConcept C109316439 @default.
• W2110298924 hasConcept C121608353 @default.
• W2110298924 hasConcept C126322002 @default.
• W2110298924 hasConcept C143998085 @default.
• W2110298924 hasConcept C185592680 @default.
• W2110298924 hasConcept C202751555 @default.
• W2110298924 hasConcept C2776235491 @default.
• W2110298924 hasConcept C2776256026 @default.
• W2110298924 hasConcept C2776694085 @default.
• W2110298924 hasConcept C2777658100 @default.
• W2110298924 hasConcept C2778239845 @default.
• W2110298924 hasConcept C2780192828 @default.
• W2110298924 hasConcept C2780210213 @default.
• W2110298924 hasConcept C2780783641 @default.
• W2110298924 hasConcept C29730261 @default.
• W2110298924 hasConcept C502942594 @default.
• W2110298924 hasConcept C526805850 @default.
• W2110298924 hasConcept C55493867 @default.
• W2110298924 hasConcept C71924100 @default.
• W2110298924 hasConcept C98274493 @default.
• W2110298924 hasConceptScore W2110298924C109316439 @default.
• W2110298924 hasConceptScore W2110298924C121608353 @default.
• W2110298924 hasConceptScore W2110298924C126322002 @default.
• W2110298924 hasConceptScore W2110298924C143998085 @default.
• W2110298924 hasConceptScore W2110298924C185592680 @default.
• W2110298924 hasConceptScore W2110298924C202751555 @default.
• W2110298924 hasConceptScore W2110298924C2776235491 @default.
• W2110298924 hasConceptScore W2110298924C2776256026 @default.
• W2110298924 hasConceptScore W2110298924C2776694085 @default.
• W2110298924 hasConceptScore W2110298924C2777658100 @default.
• W2110298924 hasConceptScore W2110298924C2778239845 @default.
• W2110298924 hasConceptScore W2110298924C2780192828 @default.
• W2110298924 hasConceptScore W2110298924C2780210213 @default.
• W2110298924 hasConceptScore W2110298924C2780783641 @default.
• W2110298924 hasConceptScore W2110298924C29730261 @default.
• W2110298924 hasConceptScore W2110298924C502942594 @default.
• W2110298924 hasConceptScore W2110298924C526805850 @default.

• next