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- W2110306514 abstract "The intraperitoneal penetration of cefotetan was studied after a 1-g intravenous injection in 25 patients undergoing elective gastrointestinal surgery. Levels of peritoneal fluid were high within 10 min after administration and increased to 44% of the serum levels after 30 min, rising to 115% at 3 h. The mean concentration of cefotetan between 3 and 5 h after administration was 32.3 micrograms/ml. These findings suggest that 1 g of cefotetan administered before abdominal surgery would result in intraperitoneal cefotetan levels necessary to inhibit susceptible pathogens for 5 h or more." @default.
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- W2110306514 date "1983-08-01" @default.
- W2110306514 modified "2023-09-27" @default.
- W2110306514 title "Intraperitoneal penetration of cefotetan" @default.
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- W2110306514 doi "https://doi.org/10.1128/aac.24.2.279" @default.
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