Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110316406> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2110316406 endingPage "1010" @default.
- W2110316406 startingPage "1006" @default.
- W2110316406 abstract "Reports of ultrasound contrast agent safety have been derived mainly from retrospective databases rather than from studies specifically designed to assess safety. The purpose of this study was to prospectively determine the safety of Optison (GE Healthcare, Princeton, NJ) in routine medical practice.Patients referred for routine rest or stress two-dimensional echocardiography who had indications for contrast were enrolled. Vital signs were obtained at baseline and at intervals up to 1 hour after dosing of Optison. Patients were followed for the development of any serious adverse event (SAE), defined as an event that causes death, is life threatening, requires or prolongs hospitalization, or causes another important event, for 24 hours after Optison administration.A total of 1,039 patients were enrolled, and 76% had 24-hour follow-up. The median age was 60 years (range, 20-97 years), and 62% were men. The mean body mass index was 33 ± 9 kg/m(2). Patient comorbidities included hypertension (73%), hyperlipidemia (64%), smoking (52%), and diabetes (37%). There were significant increases in systolic blood pressure, heart rate, and respiratory rate between the baseline, 5- to 15-min, 30-min, and 60-min time points after the administration of Optison in patients undergoing stress studies but none in those undergoing rest studies. There was a total of six SAEs during the study, which were felt to be related not to Optison but rather to the stress test itself or to the patient's underlying pathology. Although two events were classified as SAEs because of hospitalization, the hospitalizations were appropriate for pathology that would have been missed without Optison use.In this large, prospective safety study of Optison during routine resting and stress echocardiography, no SAEs related to Optison developed. Optison helped define abnormalities that required appropriate hospitalization for further management." @default.
- W2110316406 created "2016-06-24" @default.
- W2110316406 creator A5028763919 @default.
- W2110316406 creator A5045816524 @default.
- W2110316406 creator A5048015356 @default.
- W2110316406 creator A5081734725 @default.
- W2110316406 date "2014-09-01" @default.
- W2110316406 modified "2023-09-30" @default.
- W2110316406 title "An Observational Study of the Occurrence of Serious Adverse Reactions among Patients Who Receive Optison in Routine Medical Practice" @default.
- W2110316406 cites W13643477 @default.
- W2110316406 cites W1969212010 @default.
- W2110316406 cites W1971661398 @default.
- W2110316406 cites W200462973 @default.
- W2110316406 cites W2011853444 @default.
- W2110316406 cites W2020239536 @default.
- W2110316406 cites W2030214693 @default.
- W2110316406 cites W2037074160 @default.
- W2110316406 cites W2041627195 @default.
- W2110316406 cites W2075020461 @default.
- W2110316406 cites W2104707461 @default.
- W2110316406 cites W2108235137 @default.
- W2110316406 cites W2114255785 @default.
- W2110316406 cites W21157812 @default.
- W2110316406 cites W2137571765 @default.
- W2110316406 cites W2169809724 @default.
- W2110316406 cites W2171539156 @default.
- W2110316406 cites W2213500965 @default.
- W2110316406 doi "https://doi.org/10.1016/j.echo.2014.04.020" @default.
- W2110316406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24930121" @default.
- W2110316406 hasPublicationYear "2014" @default.
- W2110316406 type Work @default.
- W2110316406 sameAs 2110316406 @default.
- W2110316406 citedByCount "9" @default.
- W2110316406 countsByYear W21103164062015 @default.
- W2110316406 countsByYear W21103164062016 @default.
- W2110316406 countsByYear W21103164062017 @default.
- W2110316406 countsByYear W21103164062018 @default.
- W2110316406 countsByYear W21103164062021 @default.
- W2110316406 countsByYear W21103164062023 @default.
- W2110316406 crossrefType "journal-article" @default.
- W2110316406 hasAuthorship W2110316406A5028763919 @default.
- W2110316406 hasAuthorship W2110316406A5045816524 @default.
- W2110316406 hasAuthorship W2110316406A5048015356 @default.
- W2110316406 hasAuthorship W2110316406A5081734725 @default.
- W2110316406 hasConcept C126322002 @default.
- W2110316406 hasConcept C134018914 @default.
- W2110316406 hasConcept C141071460 @default.
- W2110316406 hasConcept C167135981 @default.
- W2110316406 hasConcept C194828623 @default.
- W2110316406 hasConcept C197934379 @default.
- W2110316406 hasConcept C23131810 @default.
- W2110316406 hasConcept C2776890885 @default.
- W2110316406 hasConcept C2777953023 @default.
- W2110316406 hasConcept C2780221984 @default.
- W2110316406 hasConcept C555293320 @default.
- W2110316406 hasConcept C71924100 @default.
- W2110316406 hasConcept C8213797 @default.
- W2110316406 hasConcept C84393581 @default.
- W2110316406 hasConceptScore W2110316406C126322002 @default.
- W2110316406 hasConceptScore W2110316406C134018914 @default.
- W2110316406 hasConceptScore W2110316406C141071460 @default.
- W2110316406 hasConceptScore W2110316406C167135981 @default.
- W2110316406 hasConceptScore W2110316406C194828623 @default.
- W2110316406 hasConceptScore W2110316406C197934379 @default.
- W2110316406 hasConceptScore W2110316406C23131810 @default.
- W2110316406 hasConceptScore W2110316406C2776890885 @default.
- W2110316406 hasConceptScore W2110316406C2777953023 @default.
- W2110316406 hasConceptScore W2110316406C2780221984 @default.
- W2110316406 hasConceptScore W2110316406C555293320 @default.
- W2110316406 hasConceptScore W2110316406C71924100 @default.
- W2110316406 hasConceptScore W2110316406C8213797 @default.
- W2110316406 hasConceptScore W2110316406C84393581 @default.
- W2110316406 hasIssue "9" @default.
- W2110316406 hasLocation W21103164061 @default.
- W2110316406 hasLocation W21103164062 @default.
- W2110316406 hasOpenAccess W2110316406 @default.
- W2110316406 hasPrimaryLocation W21103164061 @default.
- W2110316406 hasRelatedWork W2041354556 @default.
- W2110316406 hasRelatedWork W2061592547 @default.
- W2110316406 hasRelatedWork W2123587639 @default.
- W2110316406 hasRelatedWork W2189166478 @default.
- W2110316406 hasRelatedWork W2296621382 @default.
- W2110316406 hasRelatedWork W2362760053 @default.
- W2110316406 hasRelatedWork W2375807291 @default.
- W2110316406 hasRelatedWork W2616683253 @default.
- W2110316406 hasRelatedWork W4200134527 @default.
- W2110316406 hasRelatedWork W4255869851 @default.
- W2110316406 hasVolume "27" @default.
- W2110316406 isParatext "false" @default.
- W2110316406 isRetracted "false" @default.
- W2110316406 magId "2110316406" @default.
- W2110316406 workType "article" @default.