Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110335488> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2110335488 endingPage "201" @default.
- W2110335488 startingPage "197" @default.
- W2110335488 abstract "The forced swim test and tail suspension test are often used in laboratory practice to identify compounds that possess antidepressant-like activity. This experiment was conducted to determine whether housing conditions per se influence the response of mice in these antidepressant screening procedures. Male NIH Swiss mice were housed individually or in groups (five per cage) for 8 weeks prior to testing. After 8 weeks, the animals were exposed to the forced swim and tail-suspension tests. Group housed mice displayed high levels of immobility in the forced swim and tail suspension tests. Desipramine injection 60 min prior testing, in doses 7.5 and 15 mg/kg, produced significant reductions in the immobility time in forced swimming and tail suspension tests. Individually housed mice, when exposed to these tests, displayed lower levels of immobility with a magnitude comparable to the effect of desipramine in group housed mice. Desipramine given to individually housed mice did not reduce the duration of immobility either in the forced swim test or in the tail suspension test. These results indicate that both tests are sensitive to housing conditions. This observation suggests that long lasting group housing may be critical to the behavioral response in these preclinical screening procedures in mice." @default.
- W2110335488 created "2016-06-24" @default.
- W2110335488 creator A5029866695 @default.
- W2110335488 creator A5053359311 @default.
- W2110335488 date "2001-03-01" @default.
- W2110335488 modified "2023-09-25" @default.
- W2110335488 title "Group housing of mice increases immobility and antidepressant sensitivity in the forced swim and tail suspension tests" @default.
- W2110335488 cites W109954717 @default.
- W2110335488 cites W1973386992 @default.
- W2110335488 cites W1976793801 @default.
- W2110335488 cites W1979420282 @default.
- W2110335488 cites W1986427793 @default.
- W2110335488 cites W1991201649 @default.
- W2110335488 cites W2000463016 @default.
- W2110335488 cites W2005594217 @default.
- W2110335488 cites W2020648890 @default.
- W2110335488 cites W2023660894 @default.
- W2110335488 cites W2025848786 @default.
- W2110335488 cites W2025868545 @default.
- W2110335488 cites W2038431088 @default.
- W2110335488 cites W2043207301 @default.
- W2110335488 cites W2062998361 @default.
- W2110335488 cites W2070703400 @default.
- W2110335488 cites W2074803499 @default.
- W2110335488 cites W2089299823 @default.
- W2110335488 cites W2089915543 @default.
- W2110335488 cites W2110303266 @default.
- W2110335488 cites W2148128722 @default.
- W2110335488 cites W2581969695 @default.
- W2110335488 doi "https://doi.org/10.1016/s0014-2999(01)00830-5" @default.
- W2110335488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11274999" @default.
- W2110335488 hasPublicationYear "2001" @default.
- W2110335488 type Work @default.
- W2110335488 sameAs 2110335488 @default.
- W2110335488 citedByCount "70" @default.
- W2110335488 countsByYear W21103354882012 @default.
- W2110335488 countsByYear W21103354882013 @default.
- W2110335488 countsByYear W21103354882014 @default.
- W2110335488 countsByYear W21103354882015 @default.
- W2110335488 countsByYear W21103354882016 @default.
- W2110335488 countsByYear W21103354882018 @default.
- W2110335488 countsByYear W21103354882019 @default.
- W2110335488 countsByYear W21103354882020 @default.
- W2110335488 countsByYear W21103354882021 @default.
- W2110335488 countsByYear W21103354882022 @default.
- W2110335488 countsByYear W21103354882023 @default.
- W2110335488 crossrefType "journal-article" @default.
- W2110335488 hasAuthorship W2110335488A5029866695 @default.
- W2110335488 hasAuthorship W2110335488A5053359311 @default.
- W2110335488 hasConcept C126322002 @default.
- W2110335488 hasConcept C134018914 @default.
- W2110335488 hasConcept C136569192 @default.
- W2110335488 hasConcept C140793950 @default.
- W2110335488 hasConcept C15744967 @default.
- W2110335488 hasConcept C2779177272 @default.
- W2110335488 hasConcept C2780250439 @default.
- W2110335488 hasConcept C2781001258 @default.
- W2110335488 hasConcept C2781161787 @default.
- W2110335488 hasConcept C71924100 @default.
- W2110335488 hasConcept C86803240 @default.
- W2110335488 hasConceptScore W2110335488C126322002 @default.
- W2110335488 hasConceptScore W2110335488C134018914 @default.
- W2110335488 hasConceptScore W2110335488C136569192 @default.
- W2110335488 hasConceptScore W2110335488C140793950 @default.
- W2110335488 hasConceptScore W2110335488C15744967 @default.
- W2110335488 hasConceptScore W2110335488C2779177272 @default.
- W2110335488 hasConceptScore W2110335488C2780250439 @default.
- W2110335488 hasConceptScore W2110335488C2781001258 @default.
- W2110335488 hasConceptScore W2110335488C2781161787 @default.
- W2110335488 hasConceptScore W2110335488C71924100 @default.
- W2110335488 hasConceptScore W2110335488C86803240 @default.
- W2110335488 hasIssue "2-3" @default.
- W2110335488 hasLocation W21103354881 @default.
- W2110335488 hasLocation W21103354882 @default.
- W2110335488 hasOpenAccess W2110335488 @default.
- W2110335488 hasPrimaryLocation W21103354881 @default.
- W2110335488 hasRelatedWork W1964192948 @default.
- W2110335488 hasRelatedWork W1966676904 @default.
- W2110335488 hasRelatedWork W1969227419 @default.
- W2110335488 hasRelatedWork W1971954112 @default.
- W2110335488 hasRelatedWork W2030862564 @default.
- W2110335488 hasRelatedWork W2052846192 @default.
- W2110335488 hasRelatedWork W2153347959 @default.
- W2110335488 hasRelatedWork W2366392177 @default.
- W2110335488 hasRelatedWork W2382856178 @default.
- W2110335488 hasRelatedWork W2407457728 @default.
- W2110335488 hasVolume "415" @default.
- W2110335488 isParatext "false" @default.
- W2110335488 isRetracted "false" @default.
- W2110335488 magId "2110335488" @default.
- W2110335488 workType "article" @default.