FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2110338499> ?p ?o ?g. }

• W2110338499 endingPage "496" @default.
• W2110338499 startingPage "481" @default.
• W2110338499 abstract "1. In the present study the relation between regional left ventricular contractile work, regional myocardial blood flow and oxygen uptake was assessed during asynchronous electrical activation. 2. In analogy to the use of the pressure-volume area for the estimation of global oxygen demand, the fibre stress-fibre strain area, as assessed regionally, was used to estimate regional oxygen demand. The more often used relation between the pressure-sarcomere length area and regional oxygen demand was also assessed. 3. Experiments were performed in six anaesthetized dogs with open chests. Regional differences in mechanical work were generated by asynchronous electrical activation of the myocardial wall. The ventricles were paced from the right atrium, the left ventricular free wall, the left ventricular apex or the right ventricular outflow tract. Regional fibre strain was measured at the epicardial anterior left ventricular free wall with a two-dimensional video technique. 4. Regional fibre stress was estimated from left ventricular pressure, the ratio of left ventricular cavity volume to wall volume, and regional deformation. Total mechanical power (TMP) was calculated from the fibre stress-fibre strain area (SSA) and the duration of the cardiac cycle (tcycle) using the equation: TMP = SSA/tcycle. Regional myocardial blood flow was measured with radioactive microspheres. Regional oxygen uptake was estimated from regional myocardial blood flow values and arteriovenous differences in oxygen content. 5. During asynchronous electrical activation, total mechanical power, pressure-sarcomere length area, myocardial blood flow and oxygen uptake were significantly lower in early than in late activated regions (P < 0.05). 6. Within the experiments, the correlation between the pressure-sarcomere length area and regional oxygen uptake was not significantly lower than the one between total mechanical power (TMP) and regional oxygen uptake (VO2,reg). However, variability of this relation between the experiments was less for total mechanical power. Pooling all experimental data revealed: VO2,reg = k1 TMP+k2, with k1 = 4.94 +/- 0.31 mol J-1 k2 = 24.2 +/- 1.9 mmol m-3 s-1 (means +/- standard error of the estimate). 7. This relation is in quantitative agreement with previously reported relations between the pressure-volume area and global oxygen demand. The results indicate that asynchronous electrical activation causes a redistribution of mechanical work and oxygen demand and that regional total mechanical power is a better and more general estimate of regional oxygen demand than the regional pressure-sarcomere length area." @default.
• W2110338499 created "2016-06-24" @default.
• W2110338499 creator A5019378102 @default.
• W2110338499 creator A5049901772 @default.
• W2110338499 creator A5071810922 @default.
• W2110338499 creator A5080175953 @default.
• W2110338499 date "1994-06-15" @default.
• W2110338499 modified "2023-10-18" @default.
• W2110338499 title "Regional fibre stress-fibre strain area as an estimate of regional blood flow and oxygen demand in the canine heart." @default.
• W2110338499 cites W1476828943 @default.
• W2110338499 cites W171776205 @default.
• W2110338499 cites W1823564252 @default.
• W2110338499 cites W1935103941 @default.
• W2110338499 cites W1982869254 @default.
• W2110338499 cites W2002406904 @default.
• W2110338499 cites W2005133683 @default.
• W2110338499 cites W2012273576 @default.
• W2110338499 cites W2027806010 @default.
• W2110338499 cites W2030322059 @default.
• W2110338499 cites W2034597769 @default.
• W2110338499 cites W2044456226 @default.
• W2110338499 cites W2049181319 @default.
• W2110338499 cites W2064776657 @default.
• W2110338499 cites W2075917799 @default.
• W2110338499 cites W2092270437 @default.
• W2110338499 cites W2106490434 @default.
• W2110338499 cites W2113480513 @default.
• W2110338499 cites W2120363628 @default.
• W2110338499 cites W2135421935 @default.
• W2110338499 cites W2137977705 @default.
• W2110338499 cites W2140753150 @default.
• W2110338499 cites W2149607312 @default.
• W2110338499 cites W2160071814 @default.
• W2110338499 cites W2179149410 @default.
• W2110338499 cites W2215667781 @default.
• W2110338499 cites W2278740923 @default.
• W2110338499 cites W2336387976 @default.
• W2110338499 cites W2336947814 @default.
• W2110338499 cites W2340764166 @default.
• W2110338499 cites W2344166697 @default.
• W2110338499 cites W2396673442 @default.
• W2110338499 cites W2396813945 @default.
• W2110338499 cites W2406445676 @default.
• W2110338499 cites W2410462025 @default.
• W2110338499 cites W2415804143 @default.
• W2110338499 cites W2419144890 @default.
• W2110338499 cites W2428883311 @default.
• W2110338499 cites W2428888173 @default.
• W2110338499 cites W4241474540 @default.
• W2110338499 doi "https://doi.org/10.1113/jphysiol.1994.sp020209" @default.
• W2110338499 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1155612" @default.
• W2110338499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7932236" @default.
• W2110338499 hasPublicationYear "1994" @default.
• W2110338499 type Work @default.
• W2110338499 sameAs 2110338499 @default.
• W2110338499 citedByCount "160" @default.
• W2110338499 countsByYear W21103384992012 @default.
• W2110338499 countsByYear W21103384992013 @default.
• W2110338499 countsByYear W21103384992014 @default.
• W2110338499 countsByYear W21103384992015 @default.
• W2110338499 countsByYear W21103384992016 @default.
• W2110338499 countsByYear W21103384992017 @default.
• W2110338499 countsByYear W21103384992018 @default.
• W2110338499 countsByYear W21103384992019 @default.
• W2110338499 countsByYear W21103384992020 @default.
• W2110338499 countsByYear W21103384992021 @default.
• W2110338499 countsByYear W21103384992022 @default.
• W2110338499 countsByYear W21103384992023 @default.
• W2110338499 crossrefType "journal-article" @default.
• W2110338499 hasAuthorship W2110338499A5019378102 @default.
• W2110338499 hasAuthorship W2110338499A5049901772 @default.
• W2110338499 hasAuthorship W2110338499A5071810922 @default.
• W2110338499 hasAuthorship W2110338499A5080175953 @default.
• W2110338499 hasBestOaLocation W21103384991 @default.
• W2110338499 hasConcept C105702510 @default.
• W2110338499 hasConcept C126322002 @default.
• W2110338499 hasConcept C158846371 @default.
• W2110338499 hasConcept C164705383 @default.
• W2110338499 hasConcept C178790620 @default.
• W2110338499 hasConcept C178853913 @default.
• W2110338499 hasConcept C185592680 @default.
• W2110338499 hasConcept C192562407 @default.
• W2110338499 hasConcept C207200792 @default.
• W2110338499 hasConcept C26635844 @default.
• W2110338499 hasConcept C540031477 @default.
• W2110338499 hasConcept C68731436 @default.
• W2110338499 hasConcept C71924100 @default.
• W2110338499 hasConceptScore W2110338499C105702510 @default.
• W2110338499 hasConceptScore W2110338499C126322002 @default.
• W2110338499 hasConceptScore W2110338499C158846371 @default.
• W2110338499 hasConceptScore W2110338499C164705383 @default.
• W2110338499 hasConceptScore W2110338499C178790620 @default.
• W2110338499 hasConceptScore W2110338499C178853913 @default.
• W2110338499 hasConceptScore W2110338499C185592680 @default.
• W2110338499 hasConceptScore W2110338499C192562407 @default.
• W2110338499 hasConceptScore W2110338499C207200792 @default.
• W2110338499 hasConceptScore W2110338499C26635844 @default.
• W2110338499 hasConceptScore W2110338499C540031477 @default.

• next